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220 related items for PubMed ID: 24962386

  • 1. Shikonin inhibits the proliferation of human lens epithelial cells by inducing apoptosis through ROS and caspase-dependent pathway.
    Huang WR, Zhang Y, Tang X.
    Molecules; 2014 Jun 11; 19(6):7785-97. PubMed ID: 24962386
    [Abstract] [Full Text] [Related]

  • 2. Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways.
    Jing H, Sun W, Fan J, Zhang Y, Yang J, Jia J, Li J, Guo J, Luo S, Zheng Y.
    Mol Med Rep; 2016 Apr 11; 13(4):3009-16. PubMed ID: 26935874
    [Abstract] [Full Text] [Related]

  • 3. Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells.
    Mao X, Yu CR, Li WH, Li WX.
    Cell Res; 2008 Aug 11; 18(8):879-88. PubMed ID: 18663379
    [Abstract] [Full Text] [Related]

  • 4. Induction of apoptosis by shikonin through coordinative modulation of the Bcl-2 family, p27, and p53, release of cytochrome c, and sequential activation of caspases in human colorectal carcinoma cells.
    Hsu PC, Huang YT, Tsai ML, Wang YJ, Lin JK, Pan MH.
    J Agric Food Chem; 2004 Oct 06; 52(20):6330-7. PubMed ID: 15453709
    [Abstract] [Full Text] [Related]

  • 5. Shikonin induces apoptosis through reactive oxygen species/extracellular signal-regulated kinase pathway in osteosarcoma cells.
    Chang IC, Huang YJ, Chiang TI, Yeh CW, Hsu LS.
    Biol Pharm Bull; 2010 Oct 06; 33(5):816-24. PubMed ID: 20460760
    [Abstract] [Full Text] [Related]

  • 6. Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21(Cip1) downregulation are required for shikonin-induced apoptosis.
    Ahn J, Won M, Choi JH, Kim YS, Jung CR, Im DS, Kyun ML, Lee K, Song KB, Chung KS.
    Apoptosis; 2013 Jul 06; 18(7):870-81. PubMed ID: 23546866
    [Abstract] [Full Text] [Related]

  • 7. Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.
    Ravindran J, Gupta N, Agrawal M, Bala Bhaskar AS, Lakshmana Rao PV.
    Apoptosis; 2011 Feb 06; 16(2):145-61. PubMed ID: 21082355
    [Abstract] [Full Text] [Related]

  • 8. Shikonin inhibits prostate cancer cells metastasis by reducing matrix metalloproteinase-2/-9 expression via AKT/mTOR and ROS/ERK1/2 pathways.
    Chen Y, Zheng L, Liu J, Zhou Z, Cao X, Lv X, Chen F.
    Int Immunopharmacol; 2014 Aug 06; 21(2):447-55. PubMed ID: 24905636
    [Abstract] [Full Text] [Related]

  • 9. [Mechanisms of (2-methyl-n-butyl) shikonin induced apoptosis of gastric cancer SGC-7901 cells].
    Wang HB, Ma XQ.
    Yao Xue Xue Bao; 2012 Jun 06; 47(6):816-21. PubMed ID: 22919733
    [Abstract] [Full Text] [Related]

  • 10. Oridonin Inhibits Cell Proliferation and Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes.
    Shang CH, Zhang QQ, Zhou JH.
    Inflammation; 2016 Apr 06; 39(2):873-80. PubMed ID: 26923246
    [Abstract] [Full Text] [Related]

  • 11. Novel multiple apoptotic mechanism of shikonin in human glioma cells.
    Chen CH, Lin ML, Ong PL, Yang JT.
    Ann Surg Oncol; 2012 Sep 06; 19(9):3097-106. PubMed ID: 22446899
    [Abstract] [Full Text] [Related]

  • 12. 7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation.
    Zhu Y, Jiang Y, Shi L, Du L, Xu X, Wang E, Sun Y, Guo X, Zou B, Wang H, Wang C, Sun L, Zhen Y.
    Biomed Pharmacother; 2017 Mar 06; 87():527-538. PubMed ID: 28076833
    [Abstract] [Full Text] [Related]

  • 13. Sanguinarine induces apoptosis of human lens epithelial cells by increasing reactive oxygen species via the MAPK signaling pathway.
    Zhang Y, Huang WR.
    Mol Med Rep; 2019 May 06; 19(5):4449-4456. PubMed ID: 30942394
    [Abstract] [Full Text] [Related]

  • 14. Gambogenic acid induced mitochondrial-dependent apoptosis and referred to phospho-Erk1/2 and phospho-p38 MAPK in human hepatoma HepG2 cells.
    Yan F, Wang M, Li J, Cheng H, Su J, Wang X, Wu H, Xia L, Li X, Chang HC, Li Q.
    Environ Toxicol Pharmacol; 2012 Mar 06; 33(2):181-90. PubMed ID: 22222560
    [Abstract] [Full Text] [Related]

  • 15. β-lapachone significantly increases the effect of ionizing radiation to cause mitochondrial apoptosis via JNK activation in cancer cells.
    Park MT, Song MJ, Lee H, Oh ET, Choi BH, Jeong SY, Choi EK, Park HJ.
    PLoS One; 2011 Mar 06; 6(10):e25976. PubMed ID: 21998736
    [Abstract] [Full Text] [Related]

  • 16. Epigallocatechin gallate protects against oxidative stress-induced mitochondria-dependent apoptosis in human lens epithelial cells.
    Yao K, Ye P, Zhang L, Tan J, Tang X, Zhang Y.
    Mol Vis; 2008 Jan 31; 14():217-23. PubMed ID: 18334937
    [Abstract] [Full Text] [Related]

  • 17. A novel synthetic analog of Militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells.
    Yoon DH, Lim MH, Lee YR, Sung GH, Lee TH, Jeon BH, Cho JY, Song WO, Park H, Choi S, Kim TW.
    Toxicol Appl Pharmacol; 2013 Dec 15; 273(3):659-71. PubMed ID: 24161344
    [Abstract] [Full Text] [Related]

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  • 20. Honokiol inhibits tumor necrosis factor-α-stimulated rat aortic smooth muscle cell proliferation via caspase- and mitochondrial-dependent apoptosis.
    Fan S, Li X, Lin J, Chen S, Shan J, Qi G.
    Inflammation; 2014 Feb 15; 37(1):17-26. PubMed ID: 23933846
    [Abstract] [Full Text] [Related]

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