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Journal Abstract Search

247 related items for PubMed ID: 24980256

  • 1. Long-term chronic toxicity testing using human pluripotent stem cell-derived hepatocytes.
    Holmgren G, Sjögren AK, Barragan I, Sabirsh A, Sartipy P, Synnergren J, Björquist P, Ingelman-Sundberg M, Andersson TB, Edsbagge J.
    Drug Metab Dispos; 2014 Sep; 42(9):1401-6. PubMed ID: 24980256
    [Abstract] [Full Text] [Related]

  • 2. Concise review: Human pluripotent stem cell-based models for cardiac and hepatic toxicity assessment.
    Sartipy P, Björquist P.
    Stem Cells; 2011 May; 29(5):744-8. PubMed ID: 21433222
    [Abstract] [Full Text] [Related]

  • 3. Long-term and mechanistic evaluation of drug-induced liver injury in Upcyte human hepatocytes.
    Tolosa L, Jiménez N, Pelechá M, Castell JV, Gómez-Lechón MJ, Donato MT.
    Arch Toxicol; 2019 Feb; 93(2):519-532. PubMed ID: 30426164
    [Abstract] [Full Text] [Related]

  • 4. 3D engineered In vitro hepatospheroids for studying drug toxicity and metabolism.
    Chitrangi S, Nair P, Khanna A.
    Toxicol In Vitro; 2017 Feb; 38():8-18. PubMed ID: 27794450
    [Abstract] [Full Text] [Related]

  • 5. Hepatic cells derived from human skin progenitors show a typical phospholipidotic response upon exposure to amiodarone.
    Natale A, Boeckmans J, Desmae T, De Boe V, De Kock J, Vanhaecke T, Rogiers V, Rodrigues RM.
    Toxicol Lett; 2018 Mar 01; 284():184-194. PubMed ID: 29248575
    [Abstract] [Full Text] [Related]

  • 6. Morphological and Functional Characterization and Assessment of iPSC-Derived Hepatocytes for In Vitro Toxicity Testing.
    Lu J, Einhorn S, Venkatarangan L, Miller M, Mann DA, Watkins PB, LeCluyse E.
    Toxicol Sci; 2015 Sep 01; 147(1):39-54. PubMed ID: 26092927
    [Abstract] [Full Text] [Related]

  • 7. High-content assays for hepatotoxicity using induced pluripotent stem cell-derived cells.
    Sirenko O, Hesley J, Rusyn I, Cromwell EF.
    Assay Drug Dev Technol; 2014 Sep 01; 12(1):43-54. PubMed ID: 24229356
    [Abstract] [Full Text] [Related]

  • 8. A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity.
    Kostadinova R, Boess F, Applegate D, Suter L, Weiser T, Singer T, Naughton B, Roth A.
    Toxicol Appl Pharmacol; 2013 Apr 01; 268(1):1-16. PubMed ID: 23352505
    [Abstract] [Full Text] [Related]

  • 9. Biotransformation of diclofenac and effects on the metabolome of primary human hepatocytes upon repeated dose exposure.
    Mueller D, Müller-Vieira U, Biemel KM, Tascher G, Nüssler AK, Noor F.
    Eur J Pharm Sci; 2012 Apr 11; 45(5):716-24. PubMed ID: 22330146
    [Abstract] [Full Text] [Related]

  • 10. Pluripotent stem cell derived hepatocyte like cells and their potential in toxicity screening.
    Greenhough S, Medine CN, Hay DC.
    Toxicology; 2010 Dec 30; 278(3):250-5. PubMed ID: 20674645
    [Abstract] [Full Text] [Related]

  • 11. One Standardized Differentiation Procedure Robustly Generates Homogenous Hepatocyte Cultures Displaying Metabolic Diversity from a Large Panel of Human Pluripotent Stem Cells.
    Asplund A, Pradip A, van Giezen M, Aspegren A, Choukair H, Rehnström M, Jacobsson S, Ghosheh N, El Hajjam D, Holmgren S, Larsson S, Benecke J, Butron M, Wigander A, Noaksson K, Sartipy P, Björquist P, Edsbagge J, Küppers-Munther B.
    Stem Cell Rev Rep; 2016 Feb 30; 12(1):90-104. PubMed ID: 26385115
    [Abstract] [Full Text] [Related]

  • 12. Cytotoxic effects of 109 reference compounds on rat H4IIE and human HepG2 hepatocytes. III: Mechanistic assays on oxygen consumption with MitoXpress and NAD(P)H production with Alamar Blue™.
    Schoonen WG, Stevenson JC, Westerink WM, Horbach GJ.
    Toxicol In Vitro; 2012 Apr 30; 26(3):511-25. PubMed ID: 22261204
    [Abstract] [Full Text] [Related]

  • 13. Toxicity testing and drug screening using iPSC-derived hepatocytes, cardiomyocytes, and neural cells.
    Csöbönyeiová M, Polák Š, Danišovič L.
    Can J Physiol Pharmacol; 2016 Jul 30; 94(7):687-94. PubMed ID: 27128322
    [Abstract] [Full Text] [Related]

  • 14. Evaluation of the Potential Risk of Drugs to Induce Hepatotoxicity in Human-Relationships between Hepatic Steatosis Observed in Non-Clinical Toxicity Study and Hepatotoxicity in Humans.
    Goda K, Kobayashi A, Takahashi A, Takahashi T, Saito K, Maekawa K, Saito Y, Sugai S.
    Int J Mol Sci; 2017 Apr 12; 18(4):. PubMed ID: 28417920
    [Abstract] [Full Text] [Related]

  • 15. High content screening analysis of phospholipidosis: validation of a 96-well assay with CHO-K1 and HepG2 cells for the prediction of in vivo based phospholipidosis.
    van de Water FM, Havinga J, Ravesloot WT, Horbach GJ, Schoonen WG.
    Toxicol In Vitro; 2011 Dec 12; 25(8):1870-82. PubMed ID: 21651975
    [Abstract] [Full Text] [Related]

  • 16. High-content analysis in toxicology: screening substances for human toxicity potential, elucidating subcellular mechanisms and in vivo use as translational safety biomarkers.
    O'Brien PJ.
    Basic Clin Pharmacol Toxicol; 2014 Jul 12; 115(1):4-17. PubMed ID: 24641563
    [Abstract] [Full Text] [Related]

  • 17. Human induced pluripotent stem cell-derived hepatocytes for toxicology testing.
    Mann DA.
    Expert Opin Drug Metab Toxicol; 2015 Jan 12; 11(1):1-5. PubMed ID: 25385341
    [Abstract] [Full Text] [Related]

  • 18. [Developing and standardizing experimental protocols using human iPS-derived cells to predict adverse drug reactions in pre-clinical safety studies].
    Sekino Y, Sato K, Kanda Y, Ishida S.
    Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku; 2013 Jan 12; (131):25-34. PubMed ID: 24340667
    [Abstract] [Full Text] [Related]

  • 19. Human Pluripotent Stem Cells: A Unique Tool for Toxicity Testing in Pancreatic Progenitor and Endocrine Cells.
    MacFarlane EM, Bruin JE.
    Front Endocrinol (Lausanne); 2020 Jan 12; 11():604998. PubMed ID: 33542706
    [Abstract] [Full Text] [Related]

  • 20. Competency of different cell models to predict human hepatotoxic drugs.
    Gómez-Lechón MJ, Tolosa L, Conde I, Donato MT.
    Expert Opin Drug Metab Toxicol; 2014 Nov 12; 10(11):1553-68. PubMed ID: 25297626
    [Abstract] [Full Text] [Related]

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