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Journal Abstract Search

279 related items for PubMed ID: 24982162

  • 1. Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes.
    Hu J, Tepsuporn S, Meyers RM, Gostissa M, Alt FW.
    Proc Natl Acad Sci U S A; 2014 Jul 15; 111(28):10269-74. PubMed ID: 24982162
    [Abstract] [Full Text] [Related]

  • 2. Mechanisms that can promote peripheral B-cell lymphoma in ATM-deficient mice.
    Tepsuporn S, Hu J, Gostissa M, Alt FW.
    Cancer Immunol Res; 2014 Sep 15; 2(9):857-66. PubMed ID: 24913718
    [Abstract] [Full Text] [Related]

  • 3. Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.
    Gostissa M, Yan CT, Bianco JM, Cogné M, Pinaud E, Alt FW.
    Nature; 2009 Dec 10; 462(7274):803-7. PubMed ID: 20010689
    [Abstract] [Full Text] [Related]

  • 4. Mechanisms promoting translocations in editing and switching peripheral B cells.
    Wang JH, Gostissa M, Yan CT, Goff P, Hickernell T, Hansen E, Difilippantonio S, Wesemann DR, Zarrin AA, Rajewsky K, Nussenzweig A, Alt FW.
    Nature; 2009 Jul 09; 460(7252):231-6. PubMed ID: 19587764
    [Abstract] [Full Text] [Related]

  • 5. Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.
    Dong J, Panchakshari RA, Zhang T, Zhang Y, Hu J, Volpi SA, Meyers RM, Ho YJ, Du Z, Robbiani DF, Meng F, Gostissa M, Nussenzweig MC, Manis JP, Alt FW.
    Nature; 2015 Sep 03; 525(7567):134-139. PubMed ID: 26308889
    [Abstract] [Full Text] [Related]

  • 6. DSB structure impacts DNA recombination leading to class switching and chromosomal translocations in human B cells.
    So CC, Martin A.
    PLoS Genet; 2019 Apr 03; 15(4):e1008101. PubMed ID: 30946744
    [Abstract] [Full Text] [Related]

  • 7. IgH class switching and translocations use a robust non-classical end-joining pathway.
    Yan CT, Boboila C, Souza EK, Franco S, Hickernell TR, Murphy M, Gumaste S, Geyer M, Zarrin AA, Manis JP, Rajewsky K, Alt FW.
    Nature; 2007 Sep 27; 449(7161):478-82. PubMed ID: 17713479
    [Abstract] [Full Text] [Related]

  • 8. Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching.
    Wang JH, Alt FW, Gostissa M, Datta A, Murphy M, Alimzhanov MB, Coakley KM, Rajewsky K, Manis JP, Yan CT.
    J Exp Med; 2008 Dec 22; 205(13):3079-90. PubMed ID: 19064702
    [Abstract] [Full Text] [Related]

  • 9. A role for AID in chromosome translocations between c-myc and the IgH variable region.
    Dorsett Y, Robbiani DF, Jankovic M, Reina-San-Martin B, Eisenreich TR, Nussenzweig MC.
    J Exp Med; 2007 Sep 03; 204(9):2225-32. PubMed ID: 17724134
    [Abstract] [Full Text] [Related]

  • 10. AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.
    Robbiani DF, Bunting S, Feldhahn N, Bothmer A, Camps J, Deroubaix S, McBride KM, Klein IA, Stone G, Eisenreich TR, Ried T, Nussenzweig A, Nussenzweig MC.
    Mol Cell; 2009 Nov 25; 36(4):631-41. PubMed ID: 19941823
    [Abstract] [Full Text] [Related]

  • 11. DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions.
    Panchakshari RA, Zhang X, Kumar V, Du Z, Wei PC, Kao J, Dong J, Alt FW.
    Proc Natl Acad Sci U S A; 2018 Jan 23; 115(4):762-767. PubMed ID: 29311308
    [Abstract] [Full Text] [Related]

  • 12. Role of the translocation partner in protection against AID-dependent chromosomal translocations.
    Jankovic M, Robbiani DF, Dorsett Y, Eisenreich T, Xu Y, Tarakhovsky A, Nussenzweig A, Nussenzweig MC.
    Proc Natl Acad Sci U S A; 2010 Jan 05; 107(1):187-92. PubMed ID: 19966290
    [Abstract] [Full Text] [Related]

  • 13. Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70.
    Boboila C, Jankovic M, Yan CT, Wang JH, Wesemann DR, Zhang T, Fazeli A, Feldman L, Nussenzweig A, Nussenzweig M, Alt FW.
    Proc Natl Acad Sci U S A; 2010 Feb 16; 107(7):3034-9. PubMed ID: 20133803
    [Abstract] [Full Text] [Related]

  • 14. IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances.
    Gostissa M, Schwer B, Chang A, Dong J, Meyers RM, Marecki GT, Choi VW, Chiarle R, Zarrin AA, Alt FW.
    Proc Natl Acad Sci U S A; 2014 Feb 18; 111(7):2644-9. PubMed ID: 24550291
    [Abstract] [Full Text] [Related]

  • 15. H2AX prevents DNA breaks from progressing to chromosome breaks and translocations.
    Franco S, Gostissa M, Zha S, Lombard DB, Murphy MM, Zarrin AA, Yan C, Tepsuporn S, Morales JC, Adams MM, Lou Z, Bassing CH, Manis JP, Chen J, Carpenter PB, Alt FW.
    Mol Cell; 2006 Jan 20; 21(2):201-14. PubMed ID: 16427010
    [Abstract] [Full Text] [Related]

  • 16. Tp53 deletion in B lineage cells predisposes mice to lymphomas with oncogenic translocations.
    Rowh MA, DeMicco A, Horowitz JE, Yin B, Yang-Iott KS, Fusello AM, Hobeika E, Reth M, Bassing CH.
    Oncogene; 2011 Nov 24; 30(47):4757-64. PubMed ID: 21625223
    [Abstract] [Full Text] [Related]

  • 17. AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations.
    Robbiani DF, Bothmer A, Callen E, Reina-San-Martin B, Dorsett Y, Difilippantonio S, Bolland DJ, Chen HT, Corcoran AE, Nussenzweig A, Nussenzweig MC.
    Cell; 2008 Dec 12; 135(6):1028-38. PubMed ID: 19070574
    [Abstract] [Full Text] [Related]

  • 18. Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions.
    Zhang T, Franklin A, Boboila C, McQuay A, Gallagher MP, Manis JP, Khamlichi AA, Alt FW.
    Proc Natl Acad Sci U S A; 2010 Feb 16; 107(7):3040-5. PubMed ID: 20133637
    [Abstract] [Full Text] [Related]

  • 19. Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.
    Hasham MG, Snow KJ, Donghia NM, Branca JA, Lessard MD, Stavnezer J, Shopland LS, Mills KD.
    J Immunol; 2012 Sep 01; 189(5):2374-82. PubMed ID: 22826323
    [Abstract] [Full Text] [Related]

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