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Journal Abstract Search

166 related items for PubMed ID: 2498518

  • 21.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 22. Classical and nonclassical furo[2,3-d]pyrimidines as novel antifolates: synthesis and biological activities.
    Gangjee A, Devraj R, McGuire JJ, Kisliuk RL, Queener SF, Barrows LR.
    J Med Chem; 1994 Apr 15; 37(8):1169-76. PubMed ID: 8164259
    [Abstract] [Full Text] [Related]

  • 23. N10-substituted 5,8-dideazafolate inhibitors of glycinamide ribonucleotide transformylase.
    Caperelli CA.
    J Med Chem; 1987 Jul 15; 30(7):1254-6. PubMed ID: 3599031
    [Abstract] [Full Text] [Related]

  • 24. Synthesis and antifolate properties of 10-alkyl-5,10-dideaza analogues of methotrexate and tetrahydrofolic acid.
    DeGraw JI, Christie PH, Kisliuk RL, Gaumont Y, Sirotnak FM.
    J Med Chem; 1990 Feb 15; 33(2):673-7. PubMed ID: 2299633
    [Abstract] [Full Text] [Related]

  • 25. Structural features of 5,10-dideaza-5,6,7,8-tetrahydrofolate that determine inhibition of mammalian glycinamide ribonucleotide formyltransferase.
    Baldwin SW, Tse A, Gossett LS, Taylor EC, Rosowsky A, Shih C, Moran RG.
    Biochemistry; 1991 Feb 19; 30(7):1997-2006. PubMed ID: 1993209
    [Abstract] [Full Text] [Related]

  • 26. Folic acid-enhanced synergy for the combination of trimetrexate plus the glycinamide ribonucleotide formyltransferase inhibitor 4-[2-(2-amino-4-oxo-4,6,7,8-tetrahydro-3H-pyrimidino[5,4,6][1,4]thiazin -6-yl)-(S)-ethyl]-2,5-thienoylamino-L-glutamic acid (AG2034): comparison across sensitive and resistant human tumor cell lines.
    Faessel HM, Slocum HK, Rustum YM, Greco WR.
    Biochem Pharmacol; 1999 Mar 01; 57(5):567-77. PubMed ID: 9952321
    [Abstract] [Full Text] [Related]

  • 27. Design, synthesis and biological evaluation of 10-CF3CO-DDACTHF analogues and derivatives as inhibitors of GAR Tfase and the de novo purine biosynthetic pathway.
    Desharnais J, Hwang I, Zhang Y, Tavassoli A, Baboval J, Benkovic SJ, Wilson IA, Boger DL.
    Bioorg Med Chem; 2003 Oct 01; 11(20):4511-21. PubMed ID: 13129587
    [Abstract] [Full Text] [Related]

  • 28.
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  • 29. Synthesis and biological evaluation of N-[4-[5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl]-L-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway.
    Cheng H, Hwang I, Chong Y, Tavassoli A, Webb ME, Zhang Y, Wilson IA, Benkovic SJ, Boger DL.
    Bioorg Med Chem; 2005 May 16; 13(10):3593-9. PubMed ID: 15848772
    [Abstract] [Full Text] [Related]

  • 30. Synthesis and antifolate properties of 5,10-methylenetetrahydro-8,10-dideazaminopterin.
    DeGraw JI, Colwell WT, Kisliuk RL, Gaumont Y, Sirotnak FM.
    J Med Chem; 1986 Sep 16; 29(9):1786-9. PubMed ID: 3091834
    [Abstract] [Full Text] [Related]

  • 31. Protein structure-based design, synthesis, and biological evaluation of 5-thia-2,6-diamino-4(3H)-oxopyrimidines: potent inhibitors of glycinamide ribonucleotide transformylase with potent cell growth inhibition.
    Varney MD, Palmer CL, Romines WH, Boritzki T, Margosiak SA, Almassy R, Janson CA, Bartlett C, Howland EJ, Ferre R.
    J Med Chem; 1997 Aug 01; 40(16):2502-24. PubMed ID: 9258357
    [Abstract] [Full Text] [Related]

  • 32. AG2034: a novel inhibitor of glycinamide ribonucleotide formyltransferase.
    Boritzki TJ, Barlett CA, Zhang C, Howland EF.
    Invest New Drugs; 1996 Aug 01; 14(3):295-303. PubMed ID: 8958185
    [Abstract] [Full Text] [Related]

  • 33.
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  • 34. 10-(2-benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: a potential inhibitor of GAR transformylase and AICAR transformylase.
    Marsilje TH, Hedrick MP, Desharnais J, Capps K, Tavassoli A, Zhang Y, Wilson IA, Benkovic SJ, Boger DL.
    Bioorg Med Chem; 2003 Oct 01; 11(20):4503-9. PubMed ID: 13129586
    [Abstract] [Full Text] [Related]

  • 35.
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  • 36.
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  • 37. Inhibition of HKSV28 cell growth by 5,11-methenyl-tetrahydrohomofolate.
    Slieker LJ, Benkovic SJ.
    Mol Pharmacol; 1984 Mar 01; 25(2):294-302. PubMed ID: 6700575
    [Abstract] [Full Text] [Related]

  • 38. 10-Formyl-5,8,10-trideazafolic acid (10-formyl-TDAF): a potent inhibitor of glycinamide ribonucleotide transformylase.
    Boger DL, Haynes NE, Kitos PA, Warren MS, Ramcharan J, Marolewski AE, Benkovic SJ.
    Bioorg Med Chem; 1997 Sep 01; 5(9):1817-30. PubMed ID: 9354237
    [Abstract] [Full Text] [Related]

  • 39. Biochemistry and pharmacology of glycinamide ribonucleotide formyltransferase inhibitors: LY309887 and lometrexol.
    Mendelsohn LG, Shih C, Schultz RM, Worzalla JF.
    Invest New Drugs; 1996 Sep 01; 14(3):287-94. PubMed ID: 8958184
    [Abstract] [Full Text] [Related]

  • 40. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.
    Shih C, Chen VJ, Gossett LS, Gates SB, MacKellar WC, Habeck LL, Shackelford KA, Mendelsohn LG, Soose DJ, Patel VF, Andis SL, Bewley JR, Rayl EA, Moroson BA, Beardsley GP, Kohler W, Ratnam M, Schultz RM.
    Cancer Res; 1997 Mar 15; 57(6):1116-23. PubMed ID: 9067281
    [Abstract] [Full Text] [Related]

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