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209 related items for PubMed ID: 2499539

  • 1. Effects of eliminating a disulfide bridge within domain II of Pseudomonas aeruginosa exotoxin A.
    Madshus IH, Collier RJ.
    Infect Immun; 1989 Jul; 57(7):1873-8. PubMed ID: 2499539
    [Abstract] [Full Text] [Related]

  • 2. Pseudomonas aeruginosa cystic fibrosis clinical isolates produce exotoxin A with altered ADP-ribosyltransferase activity and cytotoxicity.
    Gallant CV, Raivio TL, Olson JC, Woods DE, Storey DG.
    Microbiology (Reading); 2000 Aug; 146 ( Pt 8)():1891-1899. PubMed ID: 10931893
    [Abstract] [Full Text] [Related]

  • 3. Refined crystallographic structure of Pseudomonas aeruginosa exotoxin A and its implications for the molecular mechanism of toxicity.
    Wedekind JE, Trame CB, Dorywalska M, Koehl P, Raschke TM, McKee M, FitzGerald D, Collier RJ, McKay DB.
    J Mol Biol; 2001 Dec 07; 314(4):823-37. PubMed ID: 11734000
    [Abstract] [Full Text] [Related]

  • 4. Pseudomonas aeruginosa exotoxin A: alterations of biological and biochemical properties resulting from mutation of glutamic acid 553 to aspartic acid.
    Douglas CM, Collier RJ.
    Biochemistry; 1990 May 29; 29(21):5043-9. PubMed ID: 1974145
    [Abstract] [Full Text] [Related]

  • 5. Conformational integrity of a recombinant toxoid of Pseudomonas aeruginosa exotoxin A containing a deletion of glutamic acid-553.
    Killeen KP, Collier RJ.
    Biochim Biophys Acta; 1992 Feb 14; 1138(2):162-6. PubMed ID: 1347236
    [Abstract] [Full Text] [Related]

  • 6. Biochemical analysis of CRM 66. A nonfunctional Pseudomonas aeruginosa exotoxin A.
    Galloway DR, Hedstrom RC, McGowan JL, Kessler SP, Wozniak DJ.
    J Biol Chem; 1989 Sep 05; 264(25):14869-73. PubMed ID: 2504713
    [Abstract] [Full Text] [Related]

  • 7. Toxoid of Pseudomonas aeruginosa exotoxin A generated by deletion of an active-site residue.
    Lukac M, Pier GB, Collier RJ.
    Infect Immun; 1988 Dec 05; 56(12):3095-8. PubMed ID: 2460407
    [Abstract] [Full Text] [Related]

  • 8. A dipeptide insertion in domain I of exotoxin A that impairs receptor binding.
    Chaudry GJ, Wilson RB, Draper RK, Clowes RC.
    J Biol Chem; 1989 Sep 05; 264(25):15151-6. PubMed ID: 2570071
    [Abstract] [Full Text] [Related]

  • 9. Cytotoxic activity of a recombinant chimaeric protein between Pseudomonas aeruginosa exotoxin A and Corynebacterium diphtheriae diphtheria toxin.
    Guidi-Rontani C.
    Mol Microbiol; 1992 May 05; 6(10):1281-7. PubMed ID: 1640830
    [Abstract] [Full Text] [Related]

  • 10. Pseudomonas aeruginosa exotoxin A: effects of mutating tyrosine-470 and tyrosine-481 to phenylalanine.
    Lukac M, Collier RJ.
    Biochemistry; 1988 Oct 04; 27(20):7629-32. PubMed ID: 2849995
    [Abstract] [Full Text] [Related]

  • 11. Exotoxin A of Pseudomonas aeruginosa: substitution of glutamic acid 553 with aspartic acid drastically reduces toxicity and enzymatic activity.
    Douglas CM, Collier RJ.
    J Bacteriol; 1987 Nov 04; 169(11):4967-71. PubMed ID: 2889718
    [Abstract] [Full Text] [Related]

  • 12. Structure-function analysis of exotoxin A proteins with mutations at histidine 426.
    Wick MJ, Cook JM, Iglewski BH.
    Infect Immun; 1992 Mar 04; 60(3):1128-39. PubMed ID: 1541528
    [Abstract] [Full Text] [Related]

  • 13. Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol.
    Ogata M, Chaudhary VK, Pastan I, FitzGerald DJ.
    J Biol Chem; 1990 Nov 25; 265(33):20678-85. PubMed ID: 2122978
    [Abstract] [Full Text] [Related]

  • 14. Active site mutations of Pseudomonas aeruginosa exotoxin A. Analysis of the His440 residue.
    Han XY, Galloway DR.
    J Biol Chem; 1995 Jan 13; 270(2):679-84. PubMed ID: 7822295
    [Abstract] [Full Text] [Related]

  • 15. Low pH-induced changes in Pseudomonas exotoxin and its domains: increased binding of Triton X-114.
    Idziorek T, FitzGerald D, Pastan I.
    Infect Immun; 1990 May 13; 58(5):1415-20. PubMed ID: 2108931
    [Abstract] [Full Text] [Related]

  • 16. Generation of neutralizing antipeptide antibodies to the enzymatic domain of Pseudomonas aeruginosa exotoxin A.
    Elzaim HS, Chopra AK, Peterson JW, Goodheart R, Heggers JP.
    Infect Immun; 1998 May 13; 66(5):2170-9. PubMed ID: 9573104
    [Abstract] [Full Text] [Related]

  • 17. Binding of monoclonal antibody specific for domain Ia/II of Pseudomonas aeruginosa exotoxin A at pH 4 strongly neutralizes exotoxin A-induced cytotoxicity in cell culture and in vivo.
    Ohtsuka H, Horigome K, Higuchi A, Nomura N, Ochi H, Yokota S, Kohzuki T, Noguchi H.
    Infect Immun; 1992 Mar 13; 60(3):1061-8. PubMed ID: 1371763
    [Abstract] [Full Text] [Related]

  • 18. Functional analysis of exotoxin A-related protein of Pseudomonas aeruginosa lacking residues 225-412.
    Guidi-Rontani C.
    FEMS Microbiol Lett; 1991 May 01; 64(1):103-9. PubMed ID: 1906825
    [Abstract] [Full Text] [Related]

  • 19. In vitro enzyme activation and folded stability of Pseudomonas aeruginosa exotoxin A and its C-terminal peptide.
    Beattie BK, Merrill AR.
    Biochemistry; 1996 Jul 16; 35(28):9042-51. PubMed ID: 8703907
    [Abstract] [Full Text] [Related]

  • 20. The crystal structure of Pseudomonas aeruginosa exotoxin domain III with nicotinamide and AMP: conformational differences with the intact exotoxin.
    Li M, Dyda F, Benhar I, Pastan I, Davies DR.
    Proc Natl Acad Sci U S A; 1995 Sep 26; 92(20):9308-12. PubMed ID: 7568123
    [Abstract] [Full Text] [Related]

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