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Journal Abstract Search

227 related items for PubMed ID: 25002321

  • 1. Structures of SMG1-UPFs complexes: SMG1 contributes to regulate UPF2-dependent activation of UPF1 in NMD.
    Melero R, Uchiyama A, Castaño R, Kataoka N, Kurosawa H, Ohno S, Yamashita A, Llorca O.
    Structure; 2014 Aug 05; 22(8):1105-1119. PubMed ID: 25002321
    [Abstract] [Full Text] [Related]

  • 2. Juggling key players in NMD initiation.
    Bono F.
    Structure; 2014 Aug 05; 22(8):1074-1075. PubMed ID: 25099951
    [Abstract] [Full Text] [Related]

  • 3. CK2-mediated TEL2 phosphorylation augments nonsense-mediated mRNA decay (NMD) by increase of SMG1 stability.
    Ahn S, Kim J, Hwang J.
    Biochim Biophys Acta; 2013 Oct 05; 1829(10):1047-55. PubMed ID: 23831331
    [Abstract] [Full Text] [Related]

  • 4. The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation.
    Melero R, Hug N, López-Perrote A, Yamashita A, Cáceres JF, Llorca O.
    Nat Commun; 2016 Feb 04; 7():10585. PubMed ID: 26841701
    [Abstract] [Full Text] [Related]

  • 5. Proteasome inhibitors and knockdown of SMG1 cause accumulation of Upf1 and Upf2 in human cells.
    Zhao X, Nogawa A, Matsunaga T, Takegami T, Nakagawa H, Ishigaki Y.
    Int J Oncol; 2014 Jan 04; 44(1):222-8. PubMed ID: 24173962
    [Abstract] [Full Text] [Related]

  • 6. Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex.
    López-Perrote A, Castaño R, Melero R, Zamarro T, Kurosawa H, Ohnishi T, Uchiyama A, Aoyagi K, Buchwald G, Kataoka N, Yamashita A, Llorca O.
    Nucleic Acids Res; 2016 Feb 29; 44(4):1909-23. PubMed ID: 26740584
    [Abstract] [Full Text] [Related]

  • 7. Cryo-EM structure of SMG1-SMG8-SMG9 complex.
    Zhu L, Li L, Qi Y, Yu Z, Xu Y.
    Cell Res; 2019 Dec 29; 29(12):1027-1034. PubMed ID: 31729466
    [Abstract] [Full Text] [Related]

  • 8. Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2.
    Clerici M, Deniaud A, Boehm V, Gehring NH, Schaffitzel C, Cusack S.
    Nucleic Acids Res; 2014 Feb 29; 42(4):2673-86. PubMed ID: 24271394
    [Abstract] [Full Text] [Related]

  • 9. SMG1 regulates adipogenesis via targeting of staufen1-mediated mRNA decay.
    Cho H, Han S, Park OH, Kim YK.
    Biochim Biophys Acta; 2013 Dec 29; 1829(12):1276-87. PubMed ID: 24185201
    [Abstract] [Full Text] [Related]

  • 10. Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways.
    Metze S, Herzog VA, Ruepp MD, Mühlemann O.
    RNA; 2013 Oct 29; 19(10):1432-48. PubMed ID: 23962664
    [Abstract] [Full Text] [Related]

  • 11. A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD.
    Nicholson P, Josi C, Kurosawa H, Yamashita A, Mühlemann O.
    Nucleic Acids Res; 2014 Aug 29; 42(14):9217-35. PubMed ID: 25053839
    [Abstract] [Full Text] [Related]

  • 12. Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity.
    Langer LM, Gat Y, Bonneau F, Conti E.
    Elife; 2020 May 29; 9():. PubMed ID: 32469312
    [Abstract] [Full Text] [Related]

  • 13. The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.
    Hug N, Cáceres JF.
    Cell Rep; 2014 Sep 25; 8(6):1845-1856. PubMed ID: 25220460
    [Abstract] [Full Text] [Related]

  • 14. Biochemical characterization of the RNA helicase UPF1 involved in nonsense-mediated mRNA decay.
    Fiorini F, Bonneau F, Le Hir H.
    Methods Enzymol; 2012 Sep 25; 511():255-74. PubMed ID: 22713324
    [Abstract] [Full Text] [Related]

  • 15. A highly conserved region essential for NMD in the Upf2 N-terminal domain.
    Fourati Z, Roy B, Millan C, Coureux PD, Kervestin S, van Tilbeurgh H, He F, Usón I, Jacobson A, Graille M.
    J Mol Biol; 2014 Nov 11; 426(22):3689-3702. PubMed ID: 25277656
    [Abstract] [Full Text] [Related]

  • 16. UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2.
    Langer LM, Kurscheidt K, Basquin J, Bonneau F, Iermak I, Basquin C, Conti E.
    Nucleic Acids Res; 2024 Jun 10; 52(10):6036-6048. PubMed ID: 38709891
    [Abstract] [Full Text] [Related]

  • 17. Nonsense-mediated mRNA decay involves two distinct Upf1-bound complexes.
    Dehecq M, Decourty L, Namane A, Proux C, Kanaan J, Le Hir H, Jacquier A, Saveanu C.
    EMBO J; 2018 Nov 02; 37(21):. PubMed ID: 30275269
    [Abstract] [Full Text] [Related]

  • 18. A network of SMG-8, SMG-9 and SMG-1 C-terminal insertion domain regulates UPF1 substrate recruitment and phosphorylation.
    Deniaud A, Karuppasamy M, Bock T, Masiulis S, Huard K, Garzoni F, Kerschgens K, Hentze MW, Kulozik AE, Beck M, Neu-Yilik G, Schaffitzel C.
    Nucleic Acids Res; 2015 Sep 03; 43(15):7600-11. PubMed ID: 26130714
    [Abstract] [Full Text] [Related]

  • 19. Insights into the Effects of Cancer Associated Mutations at the UPF2 and ATP-Binding Sites of NMD Master Regulator: UPF1.
    Kalathiya U, Padariya M, Pawlicka K, Verma CS, Houston D, Hupp TR, Alfaro JA.
    Int J Mol Sci; 2019 Nov 11; 20(22):. PubMed ID: 31718065
    [Abstract] [Full Text] [Related]

  • 20. Modulation of RNA-binding properties of the RNA helicase UPF1 by its activator UPF2.
    Xue G, Maciej VD, Machado de Amorim A, Pak M, Jayachandran U, Chakrabarti S.
    RNA; 2023 Feb 11; 29(2):178-187. PubMed ID: 36456182
    [Abstract] [Full Text] [Related]

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