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159 related items for PubMed ID: 25027740
41. Improved antitumor activity of a recombinant anti-Lewis(y) immunotoxin not requiring proteolytic activation. Kuan CT, Pastan I. Proc Natl Acad Sci U S A; 1996 Feb 06; 93(3):974-8. PubMed ID: 8577771 [Abstract] [Full Text] [Related]
42. Cisplatin-resistant neuroblastoma cells express enhanced levels of epidermal growth factor receptor (EGFR) and are sensitive to treatment with EGFR-specific toxins. Michaelis M, Bliss J, Arnold SC, Hinsch N, Rothweiler F, Deubzer HE, Witt O, Langer K, Doerr HW, Wels WS, Cinatl J. Clin Cancer Res; 2008 Oct 15; 14(20):6531-7. PubMed ID: 18927293 [Abstract] [Full Text] [Related]
43. Antitumor activity of the single-chain immunotoxin BR96 sFv-PE40 against established breast and lung tumor xenografts. Friedman PN, Chace DF, Trail PA, Siegall CB. J Immunol; 1993 Apr 01; 150(7):3054-61. PubMed ID: 8454873 [Abstract] [Full Text] [Related]
44. A method for increasing the yield of properly folded recombinant fusion proteins: single-chain immunotoxins from renaturation of bacterial inclusion bodies. Buchner J, Pastan I, Brinkmann U. Anal Biochem; 1992 Sep 01; 205(2):263-70. PubMed ID: 1332541 [Abstract] [Full Text] [Related]
45. Characterization of B1(Fv)PE38 and B1(dsFv)PE38: single-chain and disulfide-stabilized Fv immunotoxins with increased activity that cause complete remissions of established human carcinoma xenografts in nude mice. Benhar I, Pastan I. Clin Cancer Res; 1995 Sep 01; 1(9):1023-9. PubMed ID: 9816075 [Abstract] [Full Text] [Related]
46. Heterogeneity in interleukin-13 receptor expression and subunit structure in squamous cell carcinoma of head and neck: differential sensitivity to chimeric fusion proteins comprised of interleukin-13 and a mutated form of Pseudomonas exotoxin. Joshi BH, Kawakami K, Leland P, Puri RK. Clin Cancer Res; 2002 Jun 01; 8(6):1948-56. PubMed ID: 12060640 [Abstract] [Full Text] [Related]
47. Polyethylene glycol-modified chimeric toxin composed of transforming growth factor alpha and Pseudomonas exotoxin. Wang QC, Pai LH, Debinski W, FitzGerald DJ, Pastan I. Cancer Res; 1993 Oct 01; 53(19):4588-94. PubMed ID: 8402632 [Abstract] [Full Text] [Related]
48. Characterization of the B cell epitopes associated with a truncated form of Pseudomonas exotoxin (PE38) used to make immunotoxins for the treatment of cancer patients. Onda M, Nagata S, FitzGerald DJ, Beers R, Fisher RJ, Vincent JJ, Lee B, Nakamura M, Hwang J, Kreitman RJ, Hassan R, Pastan I. J Immunol; 2006 Dec 15; 177(12):8822-34. PubMed ID: 17142785 [Abstract] [Full Text] [Related]
57. Human kappa light chain targeted Pseudomonas exotoxin A--identifying human antibodies and Fab fragments with favorable characteristics for antibody-drug conjugate development. Kellner C, Bleeker WK, Lammerts van Bueren JJ, Staudinger M, Klausz K, Derer S, Glorius P, Muskulus A, de Goeij BE, van de Winkel JG, Parren PW, Valerius T, Gramatzki M, Peipp M. J Immunol Methods; 2011 Aug 31; 371(1-2):122-33. PubMed ID: 21756911 [Abstract] [Full Text] [Related]
58. Accumulation of a recombinant immunotoxin in a tumor in vivo: fewer than 1000 molecules per cell are sufficient for complete responses. Kreitman RJ, Pastan I. Cancer Res; 1998 Mar 01; 58(5):968-75. PubMed ID: 9500458 [Abstract] [Full Text] [Related]