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280 related items for PubMed ID: 25038572

  • 1. The role of Asn-212 in the catalytic mechanism of human endonuclease APE1: stopped-flow kinetic study of incision activity on a natural AP site and a tetrahydrofuran analogue.
    Kanazhevskaya LY, Koval VV, Lomzov AA, Fedorova OS.
    DNA Repair (Amst); 2014 Sep; 21():43-54. PubMed ID: 25038572
    [Abstract] [Full Text] [Related]

  • 2. Conformational dynamics of abasic DNA upon interactions with AP endonuclease 1 revealed by stopped-flow fluorescence analysis.
    Kanazhevskaya LY, Koval VV, Vorobjev YN, Fedorova OS.
    Biochemistry; 2012 Feb 14; 51(6):1306-21. PubMed ID: 22243137
    [Abstract] [Full Text] [Related]

  • 3. The role of active-site amino acid residues in the cleavage of DNA and RNA substrates by human apurinic/apyrimidinic endonuclease APE1.
    Alekseeva IV, Kuznetsova AA, Bakman AS, Fedorova OS, Kuznetsov NA.
    Biochim Biophys Acta Gen Subj; 2020 Dec 14; 1864(12):129718. PubMed ID: 32858086
    [Abstract] [Full Text] [Related]

  • 4. The role of Mg2+ and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: new insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis.
    Erzberger JP, Wilson DM.
    J Mol Biol; 1999 Jul 09; 290(2):447-57. PubMed ID: 10390343
    [Abstract] [Full Text] [Related]

  • 5. Substrate specificity of human apurinic/apyrimidinic endonuclease APE1 in the nucleotide incision repair pathway.
    Kuznetsova AA, Matveeva AG, Milov AD, Vorobjev YN, Dzuba SA, Fedorova OS, Kuznetsov NA.
    Nucleic Acids Res; 2018 Nov 30; 46(21):11454-11465. PubMed ID: 30329131
    [Abstract] [Full Text] [Related]

  • 6. Conformational transitions in human AP endonuclease 1 and its active site mutant during abasic site repair.
    Kanazhevskaya LY, Koval VV, Zharkov DO, Strauss PR, Fedorova OS.
    Biochemistry; 2010 Aug 03; 49(30):6451-61. PubMed ID: 20575528
    [Abstract] [Full Text] [Related]

  • 7. The impact of single-nucleotide polymorphisms of human apurinic/apyrimidinic endonuclease 1 on specific DNA binding and catalysis.
    Alekseeva IV, Davletgildeeva AT, Arkova OV, Kuznetsov NA, Fedorova OS.
    Biochimie; 2019 Aug 03; 163():73-83. PubMed ID: 31150756
    [Abstract] [Full Text] [Related]

  • 8. Effects of backbone contacts 3' to the abasic site on the cleavage and the product binding by human apurinic/apyrimidinic endonuclease (APE1).
    Izumi T, Schein CH, Oezguen N, Feng Y, Braun W.
    Biochemistry; 2004 Jan 27; 43(3):684-9. PubMed ID: 14730972
    [Abstract] [Full Text] [Related]

  • 9. Structural comparison of AP endonucleases from the exonuclease III family reveals new amino acid residues in human AP endonuclease 1 that are involved in incision of damaged DNA.
    Redrejo-Rodríguez M, Vigouroux A, Mursalimov A, Grin I, Alili D, Koshenov Z, Akishev Z, Maksimenko A, Bissenbaev AK, Matkarimov BT, Saparbaev M, Ishchenko AA, Moréra S.
    Biochimie; 2016 Jan 27; 128-129():20-33. PubMed ID: 27343627
    [Abstract] [Full Text] [Related]

  • 10. The Role of Active-Site Plasticity in Damaged-Nucleotide Recognition by Human Apurinic/Apyrimidinic Endonuclease APE1.
    Bulygin AA, Kuznetsova AA, Vorobjev YN, Fedorova OS, A Kuznetsov N.
    Molecules; 2020 Aug 28; 25(17):. PubMed ID: 32872297
    [Abstract] [Full Text] [Related]

  • 11. Pre-steady-state kinetic characterization of the AP endonuclease activity of human AP endonuclease 1.
    Maher RL, Bloom LB.
    J Biol Chem; 2007 Oct 19; 282(42):30577-85. PubMed ID: 17724035
    [Abstract] [Full Text] [Related]

  • 12. The role of His-83 of yeast apurinic/apyrimidinic endonuclease Apn1 in catalytic incision of abasic sites in DNA.
    Dyakonova ES, Koval VV, Lomzov AA, Ishchenko AA, Fedorova OS.
    Biochim Biophys Acta; 2015 Jun 19; 1850(6):1297-309. PubMed ID: 25766873
    [Abstract] [Full Text] [Related]

  • 13. Lys98 substitution in human AP endonuclease 1 affects the kinetic mechanism of enzyme action in base excision and nucleotide incision repair pathways.
    Timofeyeva NA, Koval VV, Ishchenko AA, Saparbaev MK, Fedorova OS.
    PLoS One; 2011 Jun 19; 6(9):e24063. PubMed ID: 21912662
    [Abstract] [Full Text] [Related]

  • 14. Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes.
    Tsutakawa SE, Shin DS, Mol CD, Izumi T, Arvai AS, Mantha AK, Szczesny B, Ivanov IN, Hosfield DJ, Maiti B, Pique ME, Frankel KA, Hitomi K, Cunningham RP, Mitra S, Tainer JA.
    J Biol Chem; 2013 Mar 22; 288(12):8445-8455. PubMed ID: 23355472
    [Abstract] [Full Text] [Related]

  • 15. A dominant-negative form of the major human abasic endonuclease enhances cellular sensitivity to laboratory and clinical DNA-damaging agents.
    McNeill DR, Wilson DM.
    Mol Cancer Res; 2007 Jan 22; 5(1):61-70. PubMed ID: 17259346
    [Abstract] [Full Text] [Related]

  • 16. Mapping the protein-DNA interface and the metal-binding site of the major human apurinic/apyrimidinic endonuclease.
    Nguyen LH, Barsky D, Erzberger JP, Wilson DM.
    J Mol Biol; 2000 May 05; 298(3):447-59. PubMed ID: 10772862
    [Abstract] [Full Text] [Related]

  • 17. Ape1 abasic endonuclease activity is regulated by magnesium and potassium concentrations and is robust on alternative DNA structures.
    Wilson DM.
    J Mol Biol; 2005 Feb 04; 345(5):1003-14. PubMed ID: 15644200
    [Abstract] [Full Text] [Related]

  • 18. Common Kinetic Mechanism of Abasic Site Recognition by Structurally Different Apurinic/Apyrimidinic Endonucleases.
    Kuznetsova AA, Senchurova SI, Ishchenko AA, Saparbaev M, Fedorova OS, Kuznetsov NA.
    Int J Mol Sci; 2021 Aug 18; 22(16):. PubMed ID: 34445579
    [Abstract] [Full Text] [Related]

  • 19. Modulation of the Apurinic/Apyrimidinic Endonuclease Activity of Human APE1 and of Its Natural Polymorphic Variants by Base Excision Repair Proteins.
    Kladova OA, Alekseeva IV, Saparbaev M, Fedorova OS, Kuznetsov NA.
    Int J Mol Sci; 2020 Sep 28; 21(19):. PubMed ID: 32998246
    [Abstract] [Full Text] [Related]

  • 20. Mutations in the alpha8 loop of human APE1 alter binding and cleavage of DNA containing an abasic site.
    Shen JC, Loeb LA.
    J Biol Chem; 2003 Nov 21; 278(47):46994-7001. PubMed ID: 12966083
    [Abstract] [Full Text] [Related]

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