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259 related items for PubMed ID: 25043760

  • 1. Protein dynamics control the progression and efficiency of the catalytic reaction cycle of the Escherichia coli DNA-repair enzyme AlkB.
    Ergel B, Gill ML, Brown L, Yu B, Palmer AG, Hunt JF.
    J Biol Chem; 2014 Oct 24; 289(43):29584-601. PubMed ID: 25043760
    [Abstract] [Full Text] [Related]

  • 2. Changes in protein dynamics of the DNA repair dioxygenase AlkB upon binding of Fe(2+) and 2-oxoglutarate.
    Bleijlevens B, Shivarattan T, van den Boom KS, de Haan A, van der Zwan G, Simpson PJ, Matthews SJ.
    Biochemistry; 2012 Apr 24; 51(16):3334-41. PubMed ID: 22443471
    [Abstract] [Full Text] [Related]

  • 3. Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB.
    Yu B, Edstrom WC, Benach J, Hamuro Y, Weber PC, Gibney BR, Hunt JF.
    Nature; 2006 Feb 16; 439(7078):879-84. PubMed ID: 16482161
    [Abstract] [Full Text] [Related]

  • 4. Enzymological and structural studies of the mechanism of promiscuous substrate recognition by the oxidative DNA repair enzyme AlkB.
    Yu B, Hunt JF.
    Proc Natl Acad Sci U S A; 2009 Aug 25; 106(34):14315-20. PubMed ID: 19706517
    [Abstract] [Full Text] [Related]

  • 5. Dynamic states of the DNA repair enzyme AlkB regulate product release.
    Bleijlevens B, Shivarattan T, Flashman E, Yang Y, Simpson PJ, Koivisto P, Sedgwick B, Schofield CJ, Matthews SJ.
    EMBO Rep; 2008 Sep 25; 9(9):872-7. PubMed ID: 18617893
    [Abstract] [Full Text] [Related]

  • 6. Insights into the Direct Oxidative Repair of Etheno Lesions: MD and QM/MM Study on the Substrate Scope of ALKBH2 and AlkB.
    Lenz SAP, Li D, Wetmore SD.
    DNA Repair (Amst); 2020 Dec 25; 96():102944. PubMed ID: 33161373
    [Abstract] [Full Text] [Related]

  • 7. The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond.
    Fedeles BI, Singh V, Delaney JC, Li D, Essigmann JM.
    J Biol Chem; 2015 Aug 21; 290(34):20734-20742. PubMed ID: 26152727
    [Abstract] [Full Text] [Related]

  • 8. AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli.
    Falnes PØ, Johansen RF, Seeberg E.
    Nature; 2002 Sep 12; 419(6903):178-82. PubMed ID: 12226668
    [Abstract] [Full Text] [Related]

  • 9. Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
    Yi C, Jia G, Hou G, Dai Q, Zhang W, Zheng G, Jian X, Yang CG, Cui Q, He C.
    Nature; 2010 Nov 11; 468(7321):330-3. PubMed ID: 21068844
    [Abstract] [Full Text] [Related]

  • 10. A Single-Turnover Kinetic Study of DNA Demethylation Catalyzed by Fe(II)/α-Ketoglutarate-Dependent Dioxygenase AlkB.
    Kanazhevskaya LY, Alekseeva IV, Fedorova OS.
    Molecules; 2019 Dec 13; 24(24):. PubMed ID: 31847292
    [Abstract] [Full Text] [Related]

  • 11. Escherichia coli single-stranded DNA binding protein SSB promotes AlkB-mediated DNA dealkylation repair.
    Nigam R, Anindya R.
    Biochem Biophys Res Commun; 2018 Feb 05; 496(2):274-279. PubMed ID: 29326044
    [Abstract] [Full Text] [Related]

  • 12. Structural and mutational analysis of Escherichia coli AlkB provides insight into substrate specificity and DNA damage searching.
    Holland PJ, Hollis T.
    PLoS One; 2010 Jan 13; 5(1):e8680. PubMed ID: 20084272
    [Abstract] [Full Text] [Related]

  • 13. Mechanistic studies on the application of DNA aptamers as inhibitors of 2-oxoglutarate-dependent oxygenases.
    Krylova SM, Koshkin V, Bagg E, Schofield CJ, Krylov SN.
    J Med Chem; 2012 Apr 12; 55(7):3546-52. PubMed ID: 22471443
    [Abstract] [Full Text] [Related]

  • 14. Replacement of non-heme Fe(II) with Cu(II) in the alpha-ketoglutarate dependent DNA repair enzyme AlkB: spectroscopic characterization of the active site.
    Bleijlevens B, Shivarattan T, Sedgwick B, Rigby SE, Matthews SJ.
    J Inorg Biochem; 2007 Jul 12; 101(7):1043-8. PubMed ID: 17553567
    [Abstract] [Full Text] [Related]

  • 15. Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage.
    Trewick SC, Henshaw TF, Hausinger RP, Lindahl T, Sedgwick B.
    Nature; 2002 Sep 12; 419(6903):174-8. PubMed ID: 12226667
    [Abstract] [Full Text] [Related]

  • 16. 1,N6-α-hydroxypropanoadenine, the acrolein adduct to adenine, is a substrate for AlkB dioxygenase.
    Dylewska M, Kuśmierek JT, Pilżys T, Poznański J, Maciejewska AM.
    Biochem J; 2017 May 16; 474(11):1837-1852. PubMed ID: 28408432
    [Abstract] [Full Text] [Related]

  • 17. Escherichia coli AlkB and single-stranded DNA binding protein SSB interaction explored by Molecular Dynamics Simulation.
    Mohan M, Pandya V, Anindya R.
    J Mol Graph Model; 2018 Sep 16; 84():29-35. PubMed ID: 29803030
    [Abstract] [Full Text] [Related]

  • 18. A non-heme iron-mediated chemical demethylation in DNA and RNA.
    Yi C, Yang CG, He C.
    Acc Chem Res; 2009 Apr 21; 42(4):519-29. PubMed ID: 19852088
    [Abstract] [Full Text] [Related]

  • 19. Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins.
    Falnes PØ.
    Nucleic Acids Res; 2004 Apr 21; 32(21):6260-7. PubMed ID: 15576352
    [Abstract] [Full Text] [Related]

  • 20. A simple but effective modeling strategy for structural properties of non-heme Fe(II) sites in proteins: test of force field models and application to proteins in the AlkB family.
    Pang X, Han K, Cui Q.
    J Comput Chem; 2013 Jul 15; 34(19):1620-35. PubMed ID: 23666816
    [Abstract] [Full Text] [Related]

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