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150 related items for PubMed ID: 25044264

  • 1. Predicted incorporation of non-native substrates by a polyketide synthase yields bioactive natural product derivatives.
    Bravo-Rodriguez K, Ismail-Ali AF, Klopries S, Kushnir S, Ismail S, Fansa EK, Wittinghofer A, Schulz F, Sanchez-Garcia E.
    Chembiochem; 2014 Sep 05; 15(13):1991-7. PubMed ID: 25044264
    [Abstract] [Full Text] [Related]

  • 2. Exploring the Promiscuous Enzymatic Activation of Unnatural Polyketide Extender Units in Vitro and in Vivo for Monensin Biosynthesis.
    Grote M, Schulz F.
    Chembiochem; 2019 May 02; 20(9):1183-1189. PubMed ID: 30629783
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  • 3. Flexible enzymatic activation of artificial polyketide extender units by Streptomyces cinnamonensis into the monensin biosynthetic pathway.
    Möller D, Kushnir S, Grote M, Ismail-Ali A, Koopmans KRM, Calo F, Heinrich S, Diehl B, Schulz F.
    Lett Appl Microbiol; 2018 Sep 02; 67(3):226-234. PubMed ID: 29927502
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  • 4. Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase.
    Sundermann U, Bravo-Rodriguez K, Klopries S, Kushnir S, Gomez H, Sanchez-Garcia E, Schulz F.
    ACS Chem Biol; 2013 Feb 15; 8(2):443-50. PubMed ID: 23181268
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  • 6. Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis.
    Bravo-Rodriguez K, Klopries S, Koopmans KRM, Sundermann U, Yahiaoui S, Arens J, Kushnir S, Schulz F, Sanchez-Garcia E.
    Chem Biol; 2015 Nov 19; 22(11):1425-1430. PubMed ID: 26526102
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  • 10. Structural and Biochemical Insight into the Recruitment of Acyl Carrier Protein-Linked Extender Units in Ansamitocin Biosynthesis.
    Zhang F, Ji H, Ali I, Deng Z, Bai L, Zheng J.
    Chembiochem; 2020 May 04; 21(9):1309-1314. PubMed ID: 31777147
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  • 11. Mechanism and specificity of an acyltransferase domain from a modular polyketide synthase.
    Dunn BJ, Cane DE, Khosla C.
    Biochemistry; 2013 Mar 19; 52(11):1839-41. PubMed ID: 23452124
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  • 12. Expanding Extender Substrate Selection for Unnatural Polyketide Biosynthesis by Acyltransferase Domain Exchange within a Modular Polyketide Synthase.
    Englund E, Schmidt M, Nava AA, Lechner A, Deng K, Jocic R, Lin Y, Roberts J, Benites VT, Kakumanu R, Gin JW, Chen Y, Liu Y, Petzold CJ, Baidoo EEK, Northen TR, Adams PD, Katz L, Yuzawa S, Keasling JD.
    J Am Chem Soc; 2023 Apr 26; 145(16):8822-8832. PubMed ID: 37057992
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  • 13. Structural Basis of a Broadly Selective Acyltransferase from the Polyketide Synthase of Splenocin.
    Li Y, Zhang W, Zhang H, Tian W, Wu L, Wang S, Zheng M, Zhang J, Sun C, Deng Z, Sun Y, Qu X, Zhou J.
    Angew Chem Int Ed Engl; 2018 May 14; 57(20):5823-5827. PubMed ID: 29536601
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  • 16. Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering.
    Koryakina I, Kasey C, McArthur JB, Lowell AN, Chemler JA, Li S, Hansen DA, Sherman DH, Williams GJ.
    ACS Chem Biol; 2017 Jan 20; 12(1):114-123. PubMed ID: 28103677
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  • 17. Protein-protein recognition between acyltransferases and acyl carrier proteins in multimodular polyketide synthases.
    Wong FT, Chen AY, Cane DE, Khosla C.
    Biochemistry; 2010 Jan 12; 49(1):95-102. PubMed ID: 19921859
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  • 18. Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations.
    Reeves CD, Murli S, Ashley GW, Piagentini M, Hutchinson CR, McDaniel R.
    Biochemistry; 2001 Dec 25; 40(51):15464-70. PubMed ID: 11747421
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  • 19. Enhancing the modularity of the modular polyketide synthases: transacylation in modular polyketide synthases catalyzed by malonyl-CoA:ACP transacylase.
    Kumar P, Koppisch AT, Cane DE, Khosla C.
    J Am Chem Soc; 2003 Nov 26; 125(47):14307-12. PubMed ID: 14624579
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  • 20. The Assembly Line Enzymology of Polyketide Biosynthesis.
    Till M, Race PR.
    Methods Mol Biol; 2016 Nov 26; 1401():31-49. PubMed ID: 26831699
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