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1221 related items for PubMed ID: 25046994

  • 1. Disease modifying effect of chronic oral treatment with a neurotrophic peptidergic compound in a triple transgenic mouse model of Alzheimer's disease.
    Kazim SF, Blanchard J, Dai CL, Tung YC, LaFerla FM, Iqbal IG, Iqbal K.
    Neurobiol Dis; 2014 Nov; 71():110-30. PubMed ID: 25046994
    [Abstract] [Full Text] [Related]

  • 2. Prevention of dendritic and synaptic deficits and cognitive impairment with a neurotrophic compound.
    Baazaoui N, Iqbal K.
    Alzheimers Res Ther; 2017 Jun 27; 9(1):45. PubMed ID: 28655344
    [Abstract] [Full Text] [Related]

  • 3. Prenatal to early postnatal neurotrophic treatment prevents Alzheimer-like behavior and pathology in mice.
    Wei W, Wang Y, Liu Y, Dai CL, Tung YC, Liu F, Iqbal K.
    Alzheimers Res Ther; 2020 Aug 27; 12(1):102. PubMed ID: 32854771
    [Abstract] [Full Text] [Related]

  • 4. Effects of the superoxide dismutase/catalase mimetic EUK-207 in a mouse model of Alzheimer's disease: protection against and interruption of progression of amyloid and tau pathology and cognitive decline.
    Clausen A, Xu X, Bi X, Baudry M.
    J Alzheimers Dis; 2012 Aug 27; 30(1):183-208. PubMed ID: 22406441
    [Abstract] [Full Text] [Related]

  • 5. Prevention of Amyloid-β and Tau Pathologies, Associated Neurodegeneration, and Cognitive Deficit by Early Treatment with a Neurotrophic Compound.
    Baazaoui N, Iqbal K.
    J Alzheimers Dis; 2017 Aug 27; 58(1):215-230. PubMed ID: 28387677
    [Abstract] [Full Text] [Related]

  • 6. Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer's disease.
    Kazim SF, Iqbal K.
    Mol Neurodegener; 2016 Jul 11; 11(1):50. PubMed ID: 27400746
    [Abstract] [Full Text] [Related]

  • 7. Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Aβ and tau pathologies in 3xTg-AD mice.
    Blanchard J, Wanka L, Tung YC, Cárdenas-Aguayo Mdel C, LaFerla FM, Iqbal K, Grundke-Iqbal I.
    Acta Neuropathol; 2010 Nov 11; 120(5):605-21. PubMed ID: 20697724
    [Abstract] [Full Text] [Related]

  • 8. Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques.
    Shin MK, Kim HG, Baek SH, Jung WR, Park DI, Park JS, Jo DG, Kim KL.
    Neurobiol Aging; 2014 May 11; 35(5):990-1001. PubMed ID: 24268884
    [Abstract] [Full Text] [Related]

  • 9. Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model.
    Zhang ZH, Wu QY, Zheng R, Chen C, Chen Y, Liu Q, Hoffmann PR, Ni JZ, Song GL.
    J Neurosci; 2017 Mar 01; 37(9):2449-2462. PubMed ID: 28137967
    [Abstract] [Full Text] [Related]

  • 10. Propranolol reduces cognitive deficits, amyloid and tau pathology in Alzheimer's transgenic mice.
    Dobarro M, Gerenu G, Ramírez MJ.
    Int J Neuropsychopharmacol; 2013 Nov 01; 16(10):2245-57. PubMed ID: 23768694
    [Abstract] [Full Text] [Related]

  • 11. Ciliary neurotrophic factor cell-based delivery prevents synaptic impairment and improves memory in mouse models of Alzheimer's disease.
    Garcia P, Youssef I, Utvik JK, Florent-Béchard S, Barthélémy V, Malaplate-Armand C, Kriem B, Stenger C, Koziel V, Olivier JL, Escanye MC, Hanse M, Allouche A, Desbène C, Yen FT, Bjerkvig R, Oster T, Niclou SP, Pillot T.
    J Neurosci; 2010 Jun 02; 30(22):7516-27. PubMed ID: 20519526
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  • 14. Sex-Dependent Differences in Spontaneous Autoimmunity in Adult 3xTg-AD Mice.
    Kapadia M, Mian MF, Michalski B, Azam AB, Ma D, Salwierz P, Christopher A, Rosa E, Zovkic IB, Forsythe P, Fahnestock M, Sakic B.
    J Alzheimers Dis; 2018 Jun 02; 63(3):1191-1205. PubMed ID: 29710702
    [Abstract] [Full Text] [Related]

  • 15. Valproic Acid Modifies Synaptic Structure and Accelerates Neurite Outgrowth Via the Glycogen Synthase Kinase-3β Signaling Pathway in an Alzheimer's Disease Model.
    Long ZM, Zhao L, Jiang R, Wang KJ, Luo SF, Zheng M, Li XF, He GQ.
    CNS Neurosci Ther; 2015 Nov 02; 21(11):887-97. PubMed ID: 26385876
    [Abstract] [Full Text] [Related]

  • 16. Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus--linking NMDA receptors and the reelin pathway.
    Mota SI, Ferreira IL, Valero J, Ferreiro E, Carvalho AL, Oliveira CR, Rego AC.
    Exp Neurol; 2014 Nov 02; 261():698-709. PubMed ID: 25128699
    [Abstract] [Full Text] [Related]

  • 17. Intranasal insulin restores insulin signaling, increases synaptic proteins, and reduces Aβ level and microglia activation in the brains of 3xTg-AD mice.
    Chen Y, Zhao Y, Dai CL, Liang Z, Run X, Iqbal K, Liu F, Gong CX.
    Exp Neurol; 2014 Nov 02; 261():610-9. PubMed ID: 24918340
    [Abstract] [Full Text] [Related]

  • 18. A novel glycogen synthase kinase-3 inhibitor 2-methyl-5-(3-{4-[(S )-methylsulfinyl]phenyl}-1-benzofuran-5-yl)-1,3,4-oxadiazole decreases tau phosphorylation and ameliorates cognitive deficits in a transgenic model of Alzheimer's disease.
    Onishi T, Iwashita H, Uno Y, Kunitomo J, Saitoh M, Kimura E, Fujita H, Uchiyama N, Kori M, Takizawa M.
    J Neurochem; 2011 Dec 02; 119(6):1330-40. PubMed ID: 21992552
    [Abstract] [Full Text] [Related]

  • 19. Effect of huprine X on β-amyloid, synaptophysin and α7 neuronal nicotinic acetylcholine receptors in the brain of 3xTg-AD and APPswe transgenic mice.
    Hedberg MM, Clos MV, Ratia M, Gonzalez D, Lithner CU, Camps P, Muñoz-Torrero D, Badia A, Giménez-Llort L, Nordberg A.
    Neurodegener Dis; 2010 Dec 02; 7(6):379-88. PubMed ID: 20689242
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