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371 related items for PubMed ID: 25053839

  • 1. A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD.
    Nicholson P, Josi C, Kurosawa H, Yamashita A, Mühlemann O.
    Nucleic Acids Res; 2014 Aug; 42(14):9217-35. PubMed ID: 25053839
    [Abstract] [Full Text] [Related]

  • 2. Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5-SMG7 and SMG6.
    Chakrabarti S, Bonneau F, Schüssler S, Eppinger E, Conti E.
    Nucleic Acids Res; 2014 Aug; 42(14):9447-60. PubMed ID: 25013172
    [Abstract] [Full Text] [Related]

  • 3. Transcript-specific characteristics determine the contribution of endo- and exonucleolytic decay pathways during the degradation of nonsense-mediated decay substrates.
    Ottens F, Boehm V, Sibley CR, Ule J, Gehring NH.
    RNA; 2017 Aug; 23(8):1224-1236. PubMed ID: 28461625
    [Abstract] [Full Text] [Related]

  • 4. N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD.
    Okada-Katsuhata Y, Yamashita A, Kutsuzawa K, Izumi N, Hirahara F, Ohno S.
    Nucleic Acids Res; 2012 Feb; 40(3):1251-66. PubMed ID: 21965535
    [Abstract] [Full Text] [Related]

  • 5. Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways.
    Metze S, Herzog VA, Ruepp MD, Mühlemann O.
    RNA; 2013 Oct; 19(10):1432-48. PubMed ID: 23962664
    [Abstract] [Full Text] [Related]

  • 6. UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2.
    Langer LM, Kurscheidt K, Basquin J, Bonneau F, Iermak I, Basquin C, Conti E.
    Nucleic Acids Res; 2024 Jun 10; 52(10):6036-6048. PubMed ID: 38709891
    [Abstract] [Full Text] [Related]

  • 7. A post-translational regulatory switch on UPF1 controls targeted mRNA degradation.
    Kurosaki T, Li W, Hoque M, Popp MW, Ermolenko DN, Tian B, Maquat LE.
    Genes Dev; 2014 Sep 01; 28(17):1900-16. PubMed ID: 25184677
    [Abstract] [Full Text] [Related]

  • 8. Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways.
    Colombo M, Karousis ED, Bourquin J, Bruggmann R, Mühlemann O.
    RNA; 2017 Feb 01; 23(2):189-201. PubMed ID: 27864472
    [Abstract] [Full Text] [Related]

  • 9. CK2-mediated TEL2 phosphorylation augments nonsense-mediated mRNA decay (NMD) by increase of SMG1 stability.
    Ahn S, Kim J, Hwang J.
    Biochim Biophys Acta; 2013 Oct 01; 1829(10):1047-55. PubMed ID: 23831331
    [Abstract] [Full Text] [Related]

  • 10. Dissecting the functions of SMG5, SMG7, and PNRC2 in nonsense-mediated mRNA decay of human cells.
    Nicholson P, Gkratsou A, Josi C, Colombo M, Mühlemann O.
    RNA; 2018 Apr 01; 24(4):557-573. PubMed ID: 29348139
    [Abstract] [Full Text] [Related]

  • 11. Structure of the Nmd4-Upf1 complex supports conservation of the nonsense-mediated mRNA decay pathway between yeast and humans.
    Barbarin-Bocahu I, Ulryck N, Rigobert A, Ruiz Gutierrez N, Decourty L, Raji M, Garkhal B, Le Hir H, Saveanu C, Graille M.
    PLoS Biol; 2024 Sep 01; 22(9):e3002821. PubMed ID: 39331656
    [Abstract] [Full Text] [Related]

  • 12. The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation.
    Melero R, Hug N, López-Perrote A, Yamashita A, Cáceres JF, Llorca O.
    Nat Commun; 2016 Feb 04; 7():10585. PubMed ID: 26841701
    [Abstract] [Full Text] [Related]

  • 13. SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity.
    Boehm V, Kueckelmann S, Gerbracht JV, Kallabis S, Britto-Borges T, Altmüller J, Krüger M, Dieterich C, Gehring NH.
    Nat Commun; 2021 Jun 25; 12(1):3965. PubMed ID: 34172724
    [Abstract] [Full Text] [Related]

  • 14. Processing bodies are not required for mammalian nonsense-mediated mRNA decay.
    Stalder L, Mühlemann O.
    RNA; 2009 Jul 25; 15(7):1265-73. PubMed ID: 19474145
    [Abstract] [Full Text] [Related]

  • 15. SMG5-PNRC2 is functionally dominant compared with SMG5-SMG7 in mammalian nonsense-mediated mRNA decay.
    Cho H, Han S, Choe J, Park SG, Choi SS, Kim YK.
    Nucleic Acids Res; 2013 Jan 25; 41(2):1319-28. PubMed ID: 23234702
    [Abstract] [Full Text] [Related]

  • 16. Role of SMG-1-mediated Upf1 phosphorylation in mammalian nonsense-mediated mRNA decay.
    Yamashita A.
    Genes Cells; 2013 Mar 25; 18(3):161-75. PubMed ID: 23356578
    [Abstract] [Full Text] [Related]

  • 17. Structures of SMG1-UPFs complexes: SMG1 contributes to regulate UPF2-dependent activation of UPF1 in NMD.
    Melero R, Uchiyama A, Castaño R, Kataoka N, Kurosawa H, Ohno S, Yamashita A, Llorca O.
    Structure; 2014 Aug 05; 22(8):1105-1119. PubMed ID: 25002321
    [Abstract] [Full Text] [Related]

  • 18. SMG6 cleavage generates metastable decay intermediates from nonsense-containing β-globin mRNA.
    Mascarenhas R, Dougherty JA, Schoenberg DR.
    PLoS One; 2013 Aug 05; 8(9):e74791. PubMed ID: 24086375
    [Abstract] [Full Text] [Related]

  • 19. The human RNA surveillance factor UPF1 is required for S phase progression and genome stability.
    Azzalin CM, Lingner J.
    Curr Biol; 2006 Feb 21; 16(4):433-9. PubMed ID: 16488880
    [Abstract] [Full Text] [Related]

  • 20. Tight intramolecular regulation of the human Upf1 helicase by its N- and C-terminal domains.
    Fiorini F, Boudvillain M, Le Hir H.
    Nucleic Acids Res; 2013 Feb 01; 41(4):2404-15. PubMed ID: 23275559
    [Abstract] [Full Text] [Related]

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