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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

259 related items for PubMed ID: 25054811

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  • 2. Design and synthesis of P1-P3 macrocyclic tertiary-alcohol-comprising HIV-1 protease inhibitors.
    Joshi A, Véron JB, Unge J, Rosenquist Å, Wallberg H, Samuelsson B, Hallberg A, Larhed M.
    J Med Chem; 2013 Nov 27; 56(22):8999-9007. PubMed ID: 24160253
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  • 3. Microwave-accelerated synthesis of P1'-extended HIV-1 protease inhibitors encompassing a tertiary alcohol in the transition-state mimicking scaffold.
    Ekegren JK, Ginman N, Johansson A, Wallberg H, Larhed M, Samuelsson B, Unge T, Hallberg A.
    J Med Chem; 2006 Mar 09; 49(5):1828-32. PubMed ID: 16509598
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  • 4. A new class of HIV-1 protease inhibitors containing a tertiary alcohol in the transition-state mimicking scaffold.
    Ekegren JK, Unge T, Safa MZ, Wallberg H, Samuelsson B, Hallberg A.
    J Med Chem; 2005 Dec 15; 48(25):8098-102. PubMed ID: 16335934
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  • 6. Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1'-P2' ligands.
    Ghosh AK, Sean Fyvie W, Brindisi M, Steffey M, Agniswamy J, Wang YF, Aoki M, Amano M, Weber IT, Mitsuya H.
    Bioorg Med Chem Lett; 2017 Nov 01; 27(21):4925-4931. PubMed ID: 28958624
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  • 11. Design, synthesis, protein-ligand X-ray structure, and biological evaluation of a series of novel macrocyclic human immunodeficiency virus-1 protease inhibitors to combat drug resistance.
    Ghosh AK, Kulkarni S, Anderson DD, Hong L, Baldridge A, Wang YF, Chumanevich AA, Kovalevsky AY, Tojo Y, Amano M, Koh Y, Tang J, Weber IT, Mitsuya H.
    J Med Chem; 2009 Dec 10; 52(23):7689-705. PubMed ID: 19746963
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  • 19. Symmetric fluoro-substituted diol-based HIV protease inhibitors. Ortho-fluorinated and meta-fluorinated P1/P1'-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacy.
    Lindberg J, Pyring D, Löwgren S, Rosenquist A, Zuccarello G, Kvarnström I, Zhang H, Vrang L, Classon B, Hallberg A, Samuelsson B, Unge T.
    Eur J Biochem; 2004 Nov 10; 271(22):4594-602. PubMed ID: 15560801
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  • 20. Design and synthesis of HIV-1 protease inhibitors for a long-acting injectable drug application.
    Kesteleyn B, Amssoms K, Schepens W, Hache G, Verschueren W, Van De Vreken W, Rombauts K, Meurs G, Sterkens P, Stoops B, Baert L, Austin N, Wegner J, Masungi C, Dierynck I, Lundgren S, Jönsson D, Parkes K, Kalayanov G, Wallberg H, Rosenquist A, Samuelsson B, Van Emelen K, Thuring JW.
    Bioorg Med Chem Lett; 2013 Jan 01; 23(1):310-7. PubMed ID: 23177258
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