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165 related items for PubMed ID: 2505746

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  • 4. The necessity of magnesium cation for acid assistance aglycone departure in catalysis by Escherichia coli (lacZ) beta-galactosidase.
    Sinnott ML, Withers SG.
    Biochem J; 1978 Nov 01; 175(2):539-46. PubMed ID: 105722
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  • 5. Catalytic consequences of experimental evolution: catalysis by a 'third-generation' evolvant of the second beta-galactosidase of Escherichia coli, ebgabcde, and by ebgabcd, a 'second-generation' evolvant containing two supposedly 'kinetically silent' mutations.
    Krishnan S, Hall BG, Sinnott ML.
    Biochem J; 1995 Dec 15; 312 ( Pt 3)(Pt 3):971-7. PubMed ID: 8554546
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  • 6. Changes in the substrate specificities of an enzyme during directed evolution of new functions.
    Hall BG.
    Biochemistry; 1981 Jul 07; 20(14):4042-9. PubMed ID: 6793063
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  • 8. The mechanism of action of beta-galactosidase. Effect of aglycone nature and -deuterium substitution on the hydrolysis of aryl galactosides.
    Sinnott ML, Souchard IJ.
    Biochem J; 1973 May 07; 133(1):89-98. PubMed ID: 4578762
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  • 9. DNA sequence analysis of artificially evolved ebg enzyme and ebg repressor genes.
    Hall BG, Betts PW, Wootton JC.
    Genetics; 1989 Dec 07; 123(4):635-48. PubMed ID: 2515108
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  • 10. Dependence upon pH of steady-state parameters for the beta-galactosidase-catalysed hydrolyses of beta-D-galactopyranosyl derivatives of different chemical types.
    Withers SG, Jullien M, Sinnott ML, Viratelle OM, Yon JM.
    Eur J Biochem; 1978 Jun 15; 87(2):249-56. PubMed ID: 27358
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  • 11. Structure-reactivity relationships for beta-galactosidase (Escherichia coli, lac Z). 4. Mechanism for reaction of nucleophiles with the galactosyl-enzyme intermediates of E461G and E461Q beta-galactosidases.
    Richard JP, Huber RE, Heo C, Amyes TL, Lin S.
    Biochemistry; 1996 Sep 24; 35(38):12387-401. PubMed ID: 8823174
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  • 12. Structure-reactivity relationships for beta-galactosidase (Escherichia coli, lac Z). 3. Evidence that Glu-461 participates in Brønsted acid-base catalysis of beta-D-galactopyranosyl group transfer.
    Richard JP, Huber RE, Lin S, Heo C, Amyes TL.
    Biochemistry; 1996 Sep 24; 35(38):12377-86. PubMed ID: 8823173
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  • 13. Regulation of newly evolved enzymes. IV. Directed evolution of the Ebg repressor.
    Hall BG.
    Genetics; 1978 Dec 24; 90(4):673-81. PubMed ID: 105963
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  • 14. Catalysis by the large subunit of the second beta-galactosidase of Escherichia coli in the absence of the small subunit.
    Calugaru SV, Hall BG, Sinnott ML.
    Biochem J; 1995 Nov 15; 312 ( Pt 1)(Pt 1):281-6. PubMed ID: 7492325
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  • 15. Determination of the roles of Glu-461 in beta-galactosidase (Escherichia coli) using site-specific mutagenesis.
    Cupples CG, Miller JH, Huber RE.
    J Biol Chem; 1990 Apr 05; 265(10):5512-8. PubMed ID: 1969405
    [Abstract] [Full Text] [Related]

  • 16. Experimental evolution of a new enzymatic function. II. Evolution of multiple functions for ebg enzyme in E. coli.
    Hall BG.
    Genetics; 1978 Jul 05; 89(3):453-65. PubMed ID: 97169
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  • 17. Structure-reactivity relationships for beta-galactosidase (Escherichia coli, lac Z). 2. Reactions of the galactosyl-enzyme intermediate with alcohols and azide ion.
    Richard JP, Westerfeld JG, Lin S, Beard J.
    Biochemistry; 1995 Sep 19; 34(37):11713-24. PubMed ID: 7547903
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  • 18. Determining the evolutionary potential of a gene.
    Hall BG, Malik HS.
    Mol Biol Evol; 1998 Aug 19; 15(8):1055-61. PubMed ID: 9718732
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  • 19. Experimental evolution of Ebg enzyme provides clues about the evolution of catalysis and to evolutionary potential.
    Hall BG.
    FEMS Microbiol Lett; 1999 May 01; 174(1):1-8. PubMed ID: 10234816
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  • 20. Oxygen-18 leaving group kinetic isotope effects on the hydrolysis of nitrophenyl glycosides. 1. beta-galactosidease-catalyzed hydrolysis.
    Rosenberg S, Kirsch JF.
    Biochemistry; 1981 May 26; 20(11):3189-96. PubMed ID: 6788082
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