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Journal Abstract Search


89 related items for PubMed ID: 2506093

  • 1. Heme prosthetic group required for acetylation of prostaglandin H synthase by aspirin.
    Chen YN, Marnett LJ.
    FASEB J; 1989 Sep; 3(11):2294-7. PubMed ID: 2506093
    [Abstract] [Full Text] [Related]

  • 2. Controlled tryptic digestion of prostaglandin H synthase. Characterization of protein fragments and enhanced rate of proteolysis of oxidatively inactivated enzyme.
    Chen YN, Bienkowski MJ, Marnett LJ.
    J Biol Chem; 1987 Dec 15; 262(35):16892-9. PubMed ID: 3119593
    [Abstract] [Full Text] [Related]

  • 3. Acetylation of prostaglandin endoperoxide synthase by N-acetylimidazole: comparison to acetylation by aspirin.
    Wells I, Marnett LJ.
    Biochemistry; 1992 Oct 13; 31(40):9520-5. PubMed ID: 1390734
    [Abstract] [Full Text] [Related]

  • 4.
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  • 5. Topography of prostaglandin H synthase. Antiinflammatory agents and the protease-sensitive arginine 253 region.
    Kulmacz RJ.
    J Biol Chem; 1989 Aug 25; 264(24):14136-44. PubMed ID: 2503512
    [Abstract] [Full Text] [Related]

  • 6. Chemical modification of prostaglandin endoperoxide synthase by N-acetylimidazole. Effect on enzymic activities and EPR spectroscopic properties.
    Scherer HJ, Karthein R, Strieder S, Ruf HH.
    Eur J Biochem; 1992 Apr 15; 205(2):751-7. PubMed ID: 1315275
    [Abstract] [Full Text] [Related]

  • 7. Topographic studies of microsomal and pure prostaglandin H synthase.
    Kulmacz RJ, Wu KK.
    Arch Biochem Biophys; 1989 Feb 01; 268(2):502-15. PubMed ID: 2492419
    [Abstract] [Full Text] [Related]

  • 8. The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases.
    DeWitt DL, el-Harith EA, Kraemer SA, Andrews MJ, Yao EF, Armstrong RL, Smith WL.
    J Biol Chem; 1990 Mar 25; 265(9):5192-8. PubMed ID: 2108169
    [Abstract] [Full Text] [Related]

  • 9. Essential histidines of prostaglandin endoperoxide synthase. His-309 is involved in heme binding.
    Shimokawa T, Smith WL.
    J Biol Chem; 1991 Apr 05; 266(10):6168-73. PubMed ID: 1901057
    [Abstract] [Full Text] [Related]

  • 10. Aspirin inhibition and acetylation of the plant cytochrome P450, allene oxide synthase, resembles that of animal prostaglandin endoperoxide H synthase.
    Pan Z, Camara B, Gardner HW, Backhaus RA.
    J Biol Chem; 1998 Jul 17; 273(29):18139-45. PubMed ID: 9660772
    [Abstract] [Full Text] [Related]

  • 11. EPR titration of ovine prostaglandin H synthase with hemin.
    Ruf HH, Schuhn D, Nastainczyk W.
    FEBS Lett; 1984 Jan 09; 165(2):293-6. PubMed ID: 6319185
    [Abstract] [Full Text] [Related]

  • 12. N-glycosylation of prostaglandin endoperoxide synthases-1 and -2 and their orientations in the endoplasmic reticulum.
    Otto JC, DeWitt DL, Smith WL.
    J Biol Chem; 1993 Aug 25; 268(24):18234-42. PubMed ID: 8349699
    [Abstract] [Full Text] [Related]

  • 13. Acetylation of prostaglandin synthase by aspirin.
    Roth GJ, Stanford N, Majerus PW.
    Proc Natl Acad Sci U S A; 1975 Aug 25; 72(8):3073-6. PubMed ID: 810797
    [Abstract] [Full Text] [Related]

  • 14. Identification of a pharmacologically distinct prostaglandin H synthase in cultured epithelial cells.
    Holtzman MJ, Turk J, Shornick LP.
    J Biol Chem; 1992 Oct 25; 267(30):21438-45. PubMed ID: 1400457
    [Abstract] [Full Text] [Related]

  • 15. Prostaglandin endoperoxide synthase. The aspirin acetylation region.
    Shimokawa T, Smith WL.
    J Biol Chem; 1992 Jun 15; 267(17):12387-92. PubMed ID: 1601897
    [Abstract] [Full Text] [Related]

  • 16. Molecular basis for the inhibition of prostanoid biosynthesis by nonsteroidal anti-inflammatory agents.
    Smith WL, DeWitt DL, Shimokawa T, Kraemer SA, Meade EA.
    Stroke; 1990 Dec 15; 21(12 Suppl):IV24-8. PubMed ID: 2175460
    [Abstract] [Full Text] [Related]

  • 17. [Effect of the modification of carboxylic groups in protohemin IX on the properties of endoperoxide prostaglandin synthetase].
    Mevkh AT, Golub NB, Varfolomeev SD, Filippovich EI, Makarov VA.
    Bioorg Khim; 1983 Aug 15; 9(8):1056-62. PubMed ID: 6439222
    [Abstract] [Full Text] [Related]

  • 18. Mechanistic insights into cyclooxygenase irreversible inactivation by aspirin.
    Tosco P, Lazzarato L.
    ChemMedChem; 2009 Jun 15; 4(6):939-45. PubMed ID: 19301318
    [Abstract] [Full Text] [Related]

  • 19. Structure-function relationships in sheep, mouse, and human prostaglandin endoperoxide G/H synthases.
    Smith WL, DeWitt DL, Kraemer SA, Andrews MJ, Hla T, Maciag T, Shimokawa T.
    Adv Prostaglandin Thromboxane Leukot Res; 1990 Jun 15; 20():14-21. PubMed ID: 2144687
    [Abstract] [Full Text] [Related]

  • 20. Kinetics of the interaction of nonsteroidal antiinflammatory drugs with prostaglandin endoperoxide synthase-1 studied by limited proteolysis.
    Kalgutkar AS, Crews BC, Marnett LJ.
    Biochemistry; 1996 Jul 16; 35(28):9076-82. PubMed ID: 8703911
    [Abstract] [Full Text] [Related]


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