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Journal Abstract Search

710 related items for PubMed ID: 25061803

  • 1. Discovery of potent cytotoxic ortho-aryl chalcones as new scaffold targeting tubulin and mitosis with affinity-based fluorescence.
    Zhu C, Zuo Y, Wang R, Liang B, Yue X, Wen G, Shang N, Huang L, Chen Y, Du J, Bu X.
    J Med Chem; 2014 Aug 14; 57(15):6364-82. PubMed ID: 25061803
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors.
    Wang G, Peng F, Cao D, Yang Z, Han X, Liu J, Wu W, He L, Ma L, Chen J, Sang Y, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2013 Nov 01; 21(21):6844-54. PubMed ID: 23993668
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
    Romagnoli R, Baraldi PG, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Sarkar T, Hamel E.
    Bioorg Med Chem; 2008 May 15; 16(10):5367-76. PubMed ID: 18440234
    [Abstract] [Full Text] [Related]

  • 4. Induction of apoptosis through tubulin inhibition in human cancer cells by new chromene-based chalcones.
    Aryapour H, Riazi GH, Ahmadian S, Foroumadi A, Mahdavi M, Emami S.
    Pharm Biol; 2012 Dec 15; 50(12):1551-60. PubMed ID: 22984888
    [Abstract] [Full Text] [Related]

  • 5. Inhibitors and promoters of tubulin polymerization: synthesis and biological evaluation of chalcones and related dienones as potential anticancer agents.
    Dyrager C, Wickström M, Fridén-Saxin M, Friberg A, Dahlén K, Wallén EA, Gullbo J, Grøtli M, Luthman K.
    Bioorg Med Chem; 2011 Apr 15; 19(8):2659-65. PubMed ID: 21459004
    [Abstract] [Full Text] [Related]

  • 6. Synthesis of benzo[d]imidazo[2,1-b]thiazole-chalcone conjugates as microtubule targeting and apoptosis inducing agents.
    Sultana F, Reddy Bonam S, Reddy VG, Nayak VL, Akunuri R, Rani Routhu S, Alarifi A, Halmuthur MSK, Kamal A.
    Bioorg Chem; 2018 Feb 15; 76():1-12. PubMed ID: 29102724
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding site.
    Wang G, Liu W, Gong Z, Huang Y, Li Y, Peng Z.
    J Enzyme Inhib Med Chem; 2020 Dec 15; 35(1):139-144. PubMed ID: 31724435
    [Abstract] [Full Text] [Related]

  • 8. Design and synthesis of novel imidazole-chalcone derivatives as microtubule protein polymerization inhibitors to treat cervical cancer and reverse cisplatin resistance.
    Liu Z, Yang Z, Ablise M.
    Bioorg Chem; 2024 Jun 15; 147():107310. PubMed ID: 38583249
    [Abstract] [Full Text] [Related]

  • 9. Synthesis, biological evaluation and molecular docking studies of a new series of chalcones containing naphthalene moiety as anticancer agents.
    Wang G, Qiu J, Xiao X, Cao A, Zhou F.
    Bioorg Chem; 2018 Feb 15; 76():249-257. PubMed ID: 29197743
    [Abstract] [Full Text] [Related]

  • 10. Identification of novel non-toxic and anti-angiogenic α-fluorinated chalcones as potent colchicine binding site inhibitors.
    Sun M, Yuan M, Kang Y, Qin J, Zhang Y, Duan Y, Wang L, Yao Y.
    J Enzyme Inhib Med Chem; 2022 Dec 15; 37(1):339-354. PubMed ID: 34979843
    [Abstract] [Full Text] [Related]

  • 11. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 15; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 12. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
    Kuo CC, Hsieh HP, Pan WY, Chen CP, Liou JP, Lee SJ, Chang YL, Chen LT, Chen CT, Chang JY.
    Cancer Res; 2004 Jul 01; 64(13):4621-8. PubMed ID: 15231674
    [Abstract] [Full Text] [Related]

  • 13. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
    Liu YN, Wang JJ, Ji YT, Zhao GD, Tang LQ, Zhang CM, Guo XL, Liu ZP.
    J Med Chem; 2016 Jun 09; 59(11):5341-55. PubMed ID: 27172319
    [Abstract] [Full Text] [Related]

  • 14. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X.
    Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540
    [Abstract] [Full Text] [Related]

  • 15. Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: synthesis and biological evaluation of antivascular activity.
    Ducki S, Rennison D, Woo M, Kendall A, Chabert JF, McGown AT, Lawrence NJ.
    Bioorg Med Chem; 2009 Nov 15; 17(22):7698-710. PubMed ID: 19837593
    [Abstract] [Full Text] [Related]

  • 16. Structure-based virtual screening of novel tubulin inhibitors and their characterization as anti-mitotic agents.
    Kim ND, Park ES, Kim YH, Moon SK, Lee SS, Ahn SK, Yu DY, No KT, Kim KH.
    Bioorg Med Chem; 2010 Oct 01; 18(19):7092-100. PubMed ID: 20810285
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 18. Synthesis of different heterocycles-linked chalcone conjugates as cytotoxic agents and tubulin polymerization inhibitors.
    Shankaraiah N, Nekkanti S, Brahma UR, Praveen Kumar N, Deshpande N, Prasanna D, Senwar KR, Jaya Lakshmi U.
    Bioorg Med Chem; 2017 Sep 01; 25(17):4805-4816. PubMed ID: 28774575
    [Abstract] [Full Text] [Related]

  • 19. Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers.
    Kamal A, Tamboli JR, Nayak VL, Adil SF, Vishnuvardhan MV, Ramakrishna S.
    Bioorg Med Chem; 2014 May 01; 22(9):2714-23. PubMed ID: 24721832
    [Abstract] [Full Text] [Related]

  • 20. [4-(imidazol-1-yl)thiazol-2-yl]phenylamines. A novel class of highly potent colchicine site binding tubulin inhibitors: synthesis and cytotoxic activity on selected human cancer cell lines.
    Mahboobi S, Sellmer A, Höcher H, Eichhorn E, Bär T, Schmidt M, Maier T, Stadlwieser JF, Beckers TL.
    J Med Chem; 2006 Sep 21; 49(19):5769-76. PubMed ID: 16970401
    [Abstract] [Full Text] [Related]

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