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Journal Abstract Search

268 related items for PubMed ID: 25063512

  • 1. Degradation of misfolded proteins by autophagy: is it a strategy for Huntington's disease treatment?
    Lin F, Qin ZH.
    J Huntingtons Dis; 2013; 2(2):149-57. PubMed ID: 25063512
    [Abstract] [Full Text] [Related]

  • 2. Huntington's disease: degradation of mutant huntingtin by autophagy.
    Sarkar S, Rubinsztein DC.
    FEBS J; 2008 Sep; 275(17):4263-70. PubMed ID: 18637946
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  • 3. Role of chaperone-mediated autophagy in degrading Huntington's disease-associated huntingtin protein.
    Qi L, Zhang XD.
    Acta Biochim Biophys Sin (Shanghai); 2014 Feb; 46(2):83-91. PubMed ID: 24323530
    [Abstract] [Full Text] [Related]

  • 4. Increased Steady-State Mutant Huntingtin mRNA in Huntington's Disease Brain.
    Liu W, Chaurette J, Pfister EL, Kennington LA, Chase KO, Bullock J, Vonsattel JP, Faull RL, Macdonald D, DiFiglia M, Zamore PD, Aronin N.
    J Huntingtons Dis; 2013 Feb; 2(4):491-500. PubMed ID: 25062733
    [Abstract] [Full Text] [Related]

  • 5. Clearance of mutant proteins as a therapeutic target in neurodegenerative diseases.
    Krainc D.
    Arch Neurol; 2010 Apr; 67(4):388-92. PubMed ID: 20385902
    [Abstract] [Full Text] [Related]

  • 6. Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.
    Ciechanover A, Kwon YT.
    Exp Mol Med; 2015 Mar 13; 47(3):e147. PubMed ID: 25766616
    [Abstract] [Full Text] [Related]

  • 7. The many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapy.
    Cortes CJ, La Spada AR.
    Drug Discov Today; 2014 Jul 13; 19(7):963-71. PubMed ID: 24632005
    [Abstract] [Full Text] [Related]

  • 8. ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models.
    Wold MS, Lim J, Lachance V, Deng Z, Yue Z.
    Mol Neurodegener; 2016 Dec 09; 11(1):76. PubMed ID: 27938392
    [Abstract] [Full Text] [Related]

  • 9. Autophagy in Huntington disease and huntingtin in autophagy.
    Martin DD, Ladha S, Ehrnhoefer DE, Hayden MR.
    Trends Neurosci; 2015 Jan 09; 38(1):26-35. PubMed ID: 25282404
    [Abstract] [Full Text] [Related]

  • 10. Neferine attenuates the protein level and toxicity of mutant huntingtin in PC-12 cells via induction of autophagy.
    Wong VK, Wu AG, Wang JR, Liu L, Law BY.
    Molecules; 2015 Feb 18; 20(3):3496-514. PubMed ID: 25699594
    [Abstract] [Full Text] [Related]

  • 11. Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease.
    Rose C, Menzies FM, Renna M, Acevedo-Arozena A, Corrochano S, Sadiq O, Brown SD, Rubinsztein DC.
    Hum Mol Genet; 2010 Jun 01; 19(11):2144-53. PubMed ID: 20190273
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  • 14. Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein.
    Bauer PO, Goswami A, Wong HK, Okuno M, Kurosawa M, Yamada M, Miyazaki H, Matsumoto G, Kino Y, Nagai Y, Nukina N.
    Nat Biotechnol; 2010 Mar 01; 28(3):256-63. PubMed ID: 20190739
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  • 17. Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications.
    Williams A, Jahreiss L, Sarkar S, Saiki S, Menzies FM, Ravikumar B, Rubinsztein DC.
    Curr Top Dev Biol; 2006 Mar 01; 76():89-101. PubMed ID: 17118264
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  • 18. Polyglutamine expansion affects huntingtin conformation in multiple Huntington's disease models.
    Daldin M, Fodale V, Cariulo C, Azzollini L, Verani M, Martufi P, Spiezia MC, Deguire SM, Cherubini M, Macdonald D, Weiss A, Bresciani A, Vonsattel JG, Petricca L, Marsh JL, Gines S, Santimone I, Marano M, Lashuel HA, Squitieri F, Caricasole A.
    Sci Rep; 2017 Jul 11; 7(1):5070. PubMed ID: 28698602
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