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Journal Abstract Search

449 related items for PubMed ID: 25063944

  • 1. 7-Amino-2-phenylpyrazolo[4,3-d]pyrimidine derivatives: structural investigations at the 5-position to target human A₁ and A(2A) adenosine receptors. Molecular modeling and pharmacological studies.
    Squarcialupi L, Colotta V, Catarzi D, Varano F, Betti M, Varani K, Vincenzi F, Borea PA, Porta N, Ciancetta A, Moro S.
    Eur J Med Chem; 2014 Sep 12; 84():614-27. PubMed ID: 25063944
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  • 4. Structural refinement of pyrazolo[4,3-d]pyrimidine derivatives to obtain highly potent and selective antagonists for the human A3 adenosine receptor.
    Squarcialupi L, Catarzi D, Varano F, Betti M, Falsini M, Vincenzi F, Ravani A, Ciancetta A, Varani K, Moro S, Colotta V.
    Eur J Med Chem; 2016 Jan 27; 108():117-133. PubMed ID: 26638043
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  • 6. 2-Phenylpyrazolo[4,3-d]pyrimidin-7-one as a new scaffold to obtain potent and selective human A3 adenosine receptor antagonists: new insights into the receptor-antagonist recognition.
    Lenzi O, Colotta V, Catarzi D, Varano F, Poli D, Filacchioni G, Varani K, Vincenzi F, Borea PA, Paoletta S, Morizzo E, Moro S.
    J Med Chem; 2009 Dec 10; 52(23):7640-52. PubMed ID: 19743865
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  • 7. Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A(1) adenosine receptor ligands.
    Giovannoni MP, Vergelli C, Cilibrizzi A, Crocetti L, Biancalani C, Graziano A, Dal Piaz V, Loza MI, Cadavid MI, Díaz JL, Gavaldà A.
    Bioorg Med Chem; 2010 Nov 15; 18(22):7890-9. PubMed ID: 20937560
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  • 9. The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA(3) adenosine receptors antagonists: new insights into structure-affinity relationship and receptor-antagonist recognition.
    Cheong SL, Dolzhenko A, Kachler S, Paoletta S, Federico S, Cacciari B, Dolzhenko A, Klotz KN, Moro S, Spalluto G, Pastorin G.
    J Med Chem; 2010 Apr 22; 53(8):3361-75. PubMed ID: 20307065
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  • 10. Identification of novel thiazolo[5,4-d]pyrimidine derivatives as human A1 and A2A adenosine receptor antagonists/inverse agonists.
    Varano F, Catarzi D, Falsini M, Vincenzi F, Pasquini S, Varani K, Colotta V.
    Bioorg Med Chem; 2018 Jul 23; 26(12):3688-3695. PubMed ID: 29880250
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  • 12. Design, synthesis, and biological evaluation of C9- and C2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as new A2A and A3 adenosine receptors antagonists.
    Baraldi PG, Fruttarolo F, Tabrizi MA, Preti D, Romagnoli R, El-Kashef H, Moorman A, Varani K, Gessi S, Merighi S, Borea PA.
    J Med Chem; 2003 Mar 27; 46(7):1229-41. PubMed ID: 12646033
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  • 15. Synthesis and evaluation of methoxy substituted 2-benzoyl-1-benzofuran derivatives as lead compounds for the development adenosine A1 and/or A2A receptor antagonists.
    Janse van Rensburg HD, Legoabe LJ, Terre'Blanche G, Aucamp J.
    Bioorg Chem; 2020 Jan 27; 94():103459. PubMed ID: 31818481
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  • 18. Synthesis and evaluation of N-substituted 2-amino-4,5-diarylpyrimidines as selective adenosine A1 receptor antagonists.
    Alachouzos G, Lenselink EB, Mulder-Krieger T, de Vries H, IJzerman AP, Louvel J.
    Eur J Med Chem; 2017 Jan 05; 125():586-602. PubMed ID: 27718474
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  • 19. Synthesis and structure-activity relationship of pyrazolo[3,4-d]pyrimidines: potent and selective adenosine A1 receptor antagonists.
    Poulsen SA, Quinn RJ.
    J Med Chem; 1996 Oct 11; 39(21):4156-61. PubMed ID: 8863792
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