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115 related items for PubMed ID: 25084526

  • 1. Facile entry to an efficient and practical enantioselective synthesis of a polycyclic cholesteryl ester transfer protein inhibitor.
    Han ZS, Xu Y, Fandrick DR, Rodriguez S, Li Z, Qu B, Gonnella NC, Sanyal S, Reeves JT, Ma S, Grinberg N, Haddad N, Krishnamurthy D, Song JJ, Yee NK, Pfrengle W, Ostermeier M, Schnaubelt J, Leuter Z, Steigmiller S, Däubler J, Stehle E, Neumann L, Trieselmann T, Tielmann P, Buba A, Hamm R, Koch G, Renner S, Dehli JR, Schmelcher F, Stange C, Mack J, Soyka R, Senanayake CH.
    Org Lett; 2014 Aug 15; 16(16):4142-5. PubMed ID: 25084526
    [Abstract] [Full Text] [Related]

  • 2. Diphenylpyridylethanamine (DPPE)-based aminoheterocycles as cholesteryl ester transfer protein inhibitors.
    Wang Y, Yang W, Finlay HJ, Harikrishnan LS, Jiang J, Kamau MG, Van Kirk K, Nirschl DS, Taylor DS, Chen AY, Yin X, Sleph PG, Yang RZ, Huang CS, Adam LP, Lawrence RM, Wexler RR, Salvati ME.
    Bioorg Med Chem Lett; 2014 Feb 01; 24(3):860-4. PubMed ID: 24424134
    [Abstract] [Full Text] [Related]

  • 3. General asymmetric hydrogenation of 2-alkyl- and 2-aryl-substituted quinoxaline derivatives catalyzed by iridium-difluorphos: unusual halide effect and synthetic application.
    Cartigny D, Berhal F, Nagano T, Phansavath P, Ayad T, Genêt JP, Ohshima T, Mashima K, Ratovelomanana-Vidal V.
    J Org Chem; 2012 May 18; 77(10):4544-56. PubMed ID: 22519599
    [Abstract] [Full Text] [Related]

  • 4. Practical synthesis of a potent bradykinin B(1) antagonist via enantioselective hydrogenation of a pyridyl N-acyl enamide.
    O'Shea PD, Gauvreau D, Gosselin F, Hughes G, Nadeau C, Roy A, Shultz CS.
    J Org Chem; 2009 Jun 19; 74(12):4547-53. PubMed ID: 19456171
    [Abstract] [Full Text] [Related]

  • 5. A practical synthesis of renin inhibitor MK-1597 (ACT-178882) via catalytic enantioselective hydrogenation and epimerization of piperidine intermediate.
    Molinaro C, Shultz S, Roy A, Lau S, Trinh T, Angelaud R, O'Shea PD, Abele S, Cameron M, Corley E, Funel JA, Steinhuebel D, Weisel M, Krska S.
    J Org Chem; 2011 Feb 18; 76(4):1062-71. PubMed ID: 21250716
    [Abstract] [Full Text] [Related]

  • 6. An efficient, stereoselective synthesis of the hydroxyethylene dipeptide isostere core for the HIV protease inhibitor A-792611.
    Engstrom K, Henry R, Hollis LS, Kotecki B, Marsden I, Pu YM, Wagaw S, Wang W.
    J Org Chem; 2006 Jul 07; 71(14):5369-72. PubMed ID: 16808529
    [Abstract] [Full Text] [Related]

  • 7. Diphenylpyridylethanamine (DPPE) derivatives as cholesteryl ester transfer protein (CETP) inhibitors.
    Harikrishnan LS, Finlay HJ, Qiao JX, Kamau MG, Jiang J, Wang TC, Li J, Cooper CB, Poss MA, Adam LP, Taylor DS, Chen AY, Yin X, Sleph PG, Yang RZ, Sitkoff DF, Galella MA, Nirschl DS, Van Kirk K, Miller AV, Huang CS, Chang M, Chen XQ, Salvati ME, Wexler RR, Lawrence RM.
    J Med Chem; 2012 Jul 12; 55(13):6162-75. PubMed ID: 22650305
    [Abstract] [Full Text] [Related]

  • 8. Facile construction of three contiguous stereogenic centers via dynamic kinetic resolution in asymmetric transfer hydrogenation of quinolines.
    Chen MW, Cai XF, Chen ZP, Shi L, Zhou YG.
    Chem Commun (Camb); 2014 Oct 25; 50(83):12526-9. PubMed ID: 25196398
    [Abstract] [Full Text] [Related]

  • 9. Improved asymmetric synthesis of 3,4-dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)phenyl]-alpha-(trifluoromethyl)-1(2H)-quinolineethanol, a potent cholesteryl ester transfer protein inhibitor.
    Rano TA, Kuo GH.
    Org Lett; 2009 Jul 02; 11(13):2812-5. PubMed ID: 19507869
    [Abstract] [Full Text] [Related]

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  • 13. Practical enantioselective process for a chiral phosphodiesterase-4 inhibitor.
    Chen CY.
    Curr Opin Drug Discov Devel; 2005 Nov 02; 8(6):709-22. PubMed ID: 16312147
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  • 16. 2D Quantitative structure-activity relationship studies on a series of cholesteryl ester transfer protein inhibitors.
    Castilho MS, Guido RV, Andricopulo AD.
    Bioorg Med Chem; 2007 Sep 15; 15(18):6242-52. PubMed ID: 17604633
    [Abstract] [Full Text] [Related]

  • 17. Catalytic asymmetric synthesis of a tertiary benzylic carbon center via phenol-directed alkene hydrogenation.
    Caille S, Crockett R, Ranganathan K, Wang X, Woo JC, Walker SD.
    J Org Chem; 2011 Jul 01; 76(13):5198-206. PubMed ID: 21630712
    [Abstract] [Full Text] [Related]

  • 18. Synthesis of pyridyl-dihydrobenzooxaphosphole ligands and their application in asymmetric hydrogenation of unfunctionalized alkenes.
    Qu B, Samankumara LP, Savoie J, Fandrick DR, Haddad N, Wei X, Ma S, Lee H, Rodriguez S, Busacca CA, Yee NK, Song JJ, Senanayake CH.
    J Org Chem; 2014 Feb 07; 79(3):993-1000. PubMed ID: 24410322
    [Abstract] [Full Text] [Related]

  • 19. 2-Arylbenzoxazoles as novel cholesteryl ester transfer protein inhibitors: optimization via array synthesis.
    Harikrishnan LS, Kamau MG, Herpin TF, Morton GC, Liu Y, Cooper CB, Salvati ME, Qiao JX, Wang TC, Adam LP, Taylor DS, Chen AY, Yin X, Seethala R, Peterson TL, Nirschl DS, Miller AV, Weigelt CA, Appiah KK, O'Connell JC, Michael Lawrence R.
    Bioorg Med Chem Lett; 2008 Apr 15; 18(8):2640-4. PubMed ID: 18374566
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  • 20. One-step synthesis of diarylpyrazolo[3,4-b]pyridines from isoflavones.
    Zhang ZT, Liang Y, Ma YQ, Xue D, Yang JL.
    J Comb Chem; 2010 Jul 12; 12(4):600-3. PubMed ID: 20524639
    [Abstract] [Full Text] [Related]

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