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Journal Abstract Search

104 related items for PubMed ID: 25086406

  • 1. The structural basis of differential inhibition of human calpain by indole and phenyl α-mercaptoacrylic acids.
    Adams SE, Rizkallah PJ, Miller DJ, Robinson EJ, Hallett MB, Allemann RK.
    J Struct Biol; 2014 Sep; 187(3):236-241. PubMed ID: 25086406
    [Abstract] [Full Text] [Related]

  • 2. A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.
    Todd B, Moore D, Deivanayagam CC, Lin GD, Chattopadhyay D, Maki M, Wang KK, Narayana SV.
    J Mol Biol; 2003 Apr 18; 328(1):131-46. PubMed ID: 12684003
    [Abstract] [Full Text] [Related]

  • 3. Conformationally restricted calpain inhibitors.
    Adams SE, Robinson EJ, Miller DJ, Rizkallah PJ, Hallett MB, Allemann RK.
    Chem Sci; 2015 Dec 01; 6(12):6865-6871. PubMed ID: 28757975
    [Abstract] [Full Text] [Related]

  • 4. Crystal structure of calpain-3 penta-EF-hand (PEF) domain - a homodimerized PEF family member with calcium bound at the fifth EF-hand.
    Partha SK, Ravulapalli R, Allingham JS, Campbell RL, Davies PL.
    FEBS J; 2014 Jul 01; 281(14):3138-49. PubMed ID: 24846670
    [Abstract] [Full Text] [Related]

  • 5. Crystal structure of human grancalcin, a member of the penta-EF-hand protein family.
    Jia J, Han Q, Borregaard N, Lollike K, Cygler M.
    J Mol Biol; 2000 Jul 28; 300(5):1271-81. PubMed ID: 10903868
    [Abstract] [Full Text] [Related]

  • 6. Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding.
    Lin GD, Chattopadhyay D, Maki M, Wang KK, Carson M, Jin L, Yuen PW, Takano E, Hatanaka M, DeLucas LJ, Narayana SV.
    Nat Struct Biol; 1997 Jul 28; 4(7):539-47. PubMed ID: 9228946
    [Abstract] [Full Text] [Related]

  • 7. Calpain inhibition by alpha-ketoamide and cyclic hemiacetal inhibitors revealed by X-ray crystallography.
    Cuerrier D, Moldoveanu T, Inoue J, Davies PL, Campbell RL.
    Biochemistry; 2006 Jun 20; 45(24):7446-52. PubMed ID: 16768440
    [Abstract] [Full Text] [Related]

  • 8. Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin.
    Hanna RA, Campbell RL, Davies PL.
    Nature; 2008 Nov 20; 456(7220):409-12. PubMed ID: 19020623
    [Abstract] [Full Text] [Related]

  • 9. Distinguishing between calpain heterodimerization and homodimerization.
    Ravulapalli R, Campbell RL, Gauthier SY, Dhe-Paganon S, Davies PL.
    FEBS J; 2009 Feb 20; 276(4):973-82. PubMed ID: 19215300
    [Abstract] [Full Text] [Related]

  • 10. A Ca(2+) switch aligns the active site of calpain.
    Moldoveanu T, Hosfield CM, Lim D, Elce JS, Jia Z, Davies PL.
    Cell; 2002 Mar 08; 108(5):649-60. PubMed ID: 11893336
    [Abstract] [Full Text] [Related]

  • 11. Structure-based design of allosteric calpain-1 inhibitors populating a novel bioactivity space.
    Kalash L, Cresser-Brown J, Habchi J, Morgan C, Miller DJ, Glen RC, Allemann RK, Bender A.
    Eur J Med Chem; 2018 Sep 05; 157():1264-1275. PubMed ID: 30195237
    [Abstract] [Full Text] [Related]

  • 12. Local structural preferences of calpastatin, the intrinsically unstructured protein inhibitor of calpain.
    Kiss R, Kovács D, Tompa P, Perczel A.
    Biochemistry; 2008 Jul 01; 47(26):6936-45. PubMed ID: 18537264
    [Abstract] [Full Text] [Related]

  • 13. An unexpected co-crystal structure of the calpain PEF(S) domain with Hfq reveals a potential chaperone function of Hfq.
    Cresser-Brown J, Rizkallah P, Jin Y, Roth C, Miller DJ, Allemann RK.
    Acta Crystallogr F Struct Biol Commun; 2020 Feb 01; 76(Pt 2):81-85. PubMed ID: 32039889
    [Abstract] [Full Text] [Related]

  • 14. Alpha-mercaptoacrylic acid derivatives as novel selective calpain inhibitors.
    Wang KK, Posner A, Raser KJ, Buroker-Kilgore M, Nath R, Hajimohammadreza I, Probert AW, Marcoux FW, Lunney EA, Hays SJ, Yuen P-W.
    Adv Exp Med Biol; 1996 Feb 01; 389():95-101. PubMed ID: 8860998
    [No Abstract] [Full Text] [Related]

  • 15. An update on the therapeutic potential of calpain inhibitors: a patent review.
    Donkor IO.
    Expert Opin Ther Pat; 2020 Sep 01; 30(9):659-675. PubMed ID: 32700591
    [Abstract] [Full Text] [Related]

  • 16. Crystal structures of calpain-E64 and -leupeptin inhibitor complexes reveal mobile loops gating the active site.
    Moldoveanu T, Campbell RL, Cuerrier D, Davies PL.
    J Mol Biol; 2004 Nov 05; 343(5):1313-26. PubMed ID: 15491615
    [Abstract] [Full Text] [Related]

  • 17. An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective.
    Wang KK, Nath R, Posner A, Raser KJ, Buroker-Kilgore M, Hajimohammadreza I, Probert A W, Marcoux FW, Ye Q, Takano E, Hatanaka M, Maki M, Caner H, Collins JL, Fergus A, Lee KS, Lunney EA, Hays SJ, Yuen P.
    Proc Natl Acad Sci U S A; 1996 Jun 25; 93(13):6687-92. PubMed ID: 8692879
    [Abstract] [Full Text] [Related]

  • 18. The beta- and gamma-CH2 of B27-WT's Leu11 and Ile18 side chains play a direct role in calpain inhibition.
    Betts R, Anagli J.
    Biochemistry; 2004 Mar 09; 43(9):2596-604. PubMed ID: 14992597
    [Abstract] [Full Text] [Related]

  • 19. Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes.
    Blanchard H, Grochulski P, Li Y, Arthur JS, Davies PL, Elce JS, Cygler M.
    Nat Struct Biol; 1997 Jul 09; 4(7):532-8. PubMed ID: 9228945
    [Abstract] [Full Text] [Related]

  • 20. Preference of calcium-dependent interactions between calmodulin-like domains of calpain and calpastatin subdomains.
    Takano E, Ma H, Yang HQ, Maki M, Hatanaka M.
    FEBS Lett; 1995 Mar 27; 362(1):93-7. PubMed ID: 7698360
    [Abstract] [Full Text] [Related]

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