These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

115 related items for PubMed ID: 25087870

  • 1. Mechanism of action of AminoCBIs: highly reactive but highly cytotoxic analogues of the duocarmycins.
    Tercel M, Pruijn FB, O'Connor PD, Liyanage HD, Atwell GJ, Alix SM.
    Chembiochem; 2014 Sep 05; 15(13):1998-2006. PubMed ID: 25087870
    [Abstract] [Full Text] [Related]

  • 2. A novel class of in vivo active anticancer agents: achiral seco-amino- and seco-hydroxycyclopropylbenz[e]indolone (seco-CBI) analogues of the duocarmycins and CC-1065.
    Sato A, McNulty L, Cox K, Kim S, Scott A, Daniell K, Summerville K, Price C, Hudson S, Kiakos K, Hartley JA, Asao T, Lee M.
    J Med Chem; 2005 Jun 02; 48(11):3903-18. PubMed ID: 15916443
    [Abstract] [Full Text] [Related]

  • 3. Interconversion and stability of duocarmycins, a new family of antitumor antibiotics: correlation to their cytotoxic and antimicrobial activities in vitro.
    Ichimura M, Ogawa T, Takahashi K, Mihara A, Takahashi I, Nakano H.
    Oncol Res; 1993 Jun 02; 5(4-5):165-71. PubMed ID: 8305742
    [Abstract] [Full Text] [Related]

  • 4. Preparation and properties of clickable amino analogues of the duocarmycins: factors that affect the efficiency of their fluorescent labelling of DNA.
    Tercel M, McManaway SP, Liyanage HD, Pruijn FB.
    ChemMedChem; 2014 Sep 02; 9(9):2193-206. PubMed ID: 25044224
    [Abstract] [Full Text] [Related]

  • 5. Selective treatment of cancer: synthesis, biological evaluation and structural elucidation of novel analogues of the antibiotic CC-1065 and the duocarmycins.
    Tietze LF, Major F, Schuberth I, Spiegl DA, Krewer B, Maksimenka K, Bringmann G, Magull J.
    Chemistry; 2007 Sep 02; 13(16):4396-409. PubMed ID: 17455190
    [Abstract] [Full Text] [Related]

  • 6. DNA sequence selective adenine alkylation, mechanism of adduct repair, and in vivo antitumor activity of the novel achiral seco-amino-cyclopropylbenz[e]indolone analogue of duocarmycin AS-I-145.
    Kiakos K, Sato A, Asao T, McHugh PJ, Lee M, Hartley JA.
    Mol Cancer Ther; 2007 Oct 02; 6(10):2708-18. PubMed ID: 17938264
    [Abstract] [Full Text] [Related]

  • 7. A novel achiral seco-amino-cyclopropylindoline (CI) analog of CC-1065 and the duocarmycins: design, synthesis and biological studies.
    Toth JL, Trzupek JD, Flores LV, Kiakos K, Hartley JA, Pennington WT, Lee M.
    Med Chem; 2005 Jan 02; 1(1):13-9. PubMed ID: 16789881
    [Abstract] [Full Text] [Related]

  • 8. Metal cation complexation and activation of reversed CPyI analogues of CC-1065 and duocarmycin SA: partitioning the effects of binding and catalysis.
    Ellis DA, Wolkenberg SE, Boger DL.
    J Am Chem Soc; 2001 Sep 26; 123(38):9299-306. PubMed ID: 11562212
    [Abstract] [Full Text] [Related]

  • 9. Solid-Phase Synthesis of Duocarmycin Analogues and the Effect of C-Terminal Substitution on Biological Activity.
    Stephenson MJ, Howell LA, O'Connell MA, Fox KR, Adcock C, Kingston J, Sheldrake H, Pors K, Collingwood SP, Searcey M.
    J Org Chem; 2015 Oct 02; 80(19):9454-67. PubMed ID: 26356089
    [Abstract] [Full Text] [Related]

  • 10. Duocarmycins, new antitumor antibiotics produced by Streptomyces; producing organisms and improved production.
    Ichimura M, Ogawa T, Katsumata S, Takahashi K, Takahashi I, Nakano H.
    J Antibiot (Tokyo); 1991 Oct 02; 44(10):1045-53. PubMed ID: 1955385
    [Abstract] [Full Text] [Related]

  • 11. Unexpected syntheses of seco-cyclopropyltetrahydroquinolines - from a radical 5-exo-trig cyclization reaction: analogs of CC-1065 and the duocarmycins.
    Pati H, Howard T, Townes H, Lingerfelt B, McNulty L, Lee M.
    Molecules; 2004 Feb 28; 9(3):125-33. PubMed ID: 18007417
    [Abstract] [Full Text] [Related]

  • 12. Establishing the parabolic relationship between reactivity and activity for derivatives and analogues of the duocarmycin and CC-1065 alkylation subunits.
    Parrish JP, Hughes TV, Hwang I, Boger DL.
    J Am Chem Soc; 2004 Jan 14; 126(1):80-1. PubMed ID: 14709069
    [Abstract] [Full Text] [Related]

  • 13. A Short Review on the Synthetic Strategies of Duocarmycin Analogs that are Powerful DNA Alkylating Agents.
    Patil PC, Satam V, Lee M.
    Anticancer Agents Med Chem; 2015 Jan 14; 15(5):616-30. PubMed ID: 25511515
    [Abstract] [Full Text] [Related]

  • 14.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 15.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 16. Novel furano analogues of duocarmycin C1 and C2: design, synthesis, and biological evaluation of seco-iso-cyclopropylfurano[2,3-e]indoline (seco-iso-CFI) and seco-cyclopropyltetrahydrofurano[2,3-f]quinoline (seco-CFQ) analogues.
    Howard TT, Lingerfelt BM, Purnell BL, Scott AE, Price CA, Townes HM, McNulty L, Handl HL, Summerville K, Hudson SJ, Bowen JP, Kiakos K, Hartley JA, Lee M.
    Bioorg Med Chem; 2002 Sep 14; 10(9):2941-52. PubMed ID: 12110316
    [Abstract] [Full Text] [Related]

  • 17. The effect of a bromide leaving group on the properties of nitro analogs of the duocarmycins as hypoxia-activated prodrugs and phosphate pre-prodrugs for antitumor therapy.
    Stevenson RJ, Denny WA, Ashoorzadeh A, Pruijn FB, van Leeuwen WF, Tercel M.
    Bioorg Med Chem; 2011 Oct 15; 19(20):5989-98. PubMed ID: 21920763
    [Abstract] [Full Text] [Related]

  • 18. DNA interstrand crosslinking agents: synthesis, DNA interactions, and cytotoxicity of dimeric achiral seco-amino-CBI and conjugates of achiral seco-amino-CBI with pyrrolobenzodiazepine (PBD).
    Purnell B, Sato A, O'kelley A, Price C, Summerville K, Hudson S, O'hare C, Kiakos K, Asao T, Lee M, Hartley JA.
    Bioorg Med Chem Lett; 2006 Nov 01; 16(21):5677-81. PubMed ID: 16919946
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and evaluation of duocarmycin and CC-1065 analogues incorporating the 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]-3-azaindol-4-one (CBA) alkylation subunit.
    Parrish JP, Kastrinsky DB, Hwang I, Boger DL.
    J Org Chem; 2003 Nov 14; 68(23):8984-90. PubMed ID: 14604371
    [Abstract] [Full Text] [Related]

  • 20.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 6.