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255 related items for PubMed ID: 25101566

  • 1. Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells.
    Siveen KS, Nguyen AH, Lee JH, Li F, Singh SS, Kumar AP, Low G, Jha S, Tergaonkar V, Ahn KS, Sethi G.
    Br J Cancer; 2014 Sep 23; 111(7):1327-37. PubMed ID: 25101566
    [Abstract] [Full Text] [Related]

  • 2. Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3.
    Subramaniam A, Shanmugam MK, Ong TH, Li F, Perumal E, Chen L, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Hui KM, Sethi G.
    Br J Pharmacol; 2013 Oct 23; 170(4):807-21. PubMed ID: 23848338
    [Abstract] [Full Text] [Related]

  • 3. Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1.
    Rajendran P, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Sethi G.
    J Cell Physiol; 2012 May 23; 227(5):2184-95. PubMed ID: 21792937
    [Abstract] [Full Text] [Related]

  • 4. Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells.
    Yang J, Cai X, Lu W, Hu C, Xu X, Yu Q, Cao P.
    Cancer Lett; 2013 Jan 28; 328(2):243-51. PubMed ID: 23032719
    [Abstract] [Full Text] [Related]

  • 5. γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent.
    Rajendran P, Li F, Manu KA, Shanmugam MK, Loo SY, Kumar AP, Sethi G.
    Br J Pharmacol; 2011 May 28; 163(2):283-98. PubMed ID: 21198544
    [Abstract] [Full Text] [Related]

  • 6. Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.
    Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G.
    J Pharmacol Exp Ther; 2010 Jul 28; 334(1):285-93. PubMed ID: 20378717
    [Abstract] [Full Text] [Related]

  • 7. Crocetin imparts antiproliferative activity via inhibiting STAT3 signaling in hepatocellular carcinoma.
    Mohan CD, Kim C, Siveen KS, Manu KA, Rangappa S, Chinnathambi A, Alharbi SA, Rangappa KS, Kumar AP, Ahn KS.
    IUBMB Life; 2021 Nov 28; 73(11):1348-1362. PubMed ID: 34514729
    [Abstract] [Full Text] [Related]

  • 8. β-Caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase.
    Kim C, Cho SK, Kapoor S, Kumar A, Vali S, Abbasi T, Kim SH, Sethi G, Ahn KS.
    Mol Carcinog; 2014 Oct 28; 53(10):793-806. PubMed ID: 23765383
    [Abstract] [Full Text] [Related]

  • 9. Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model.
    Shanmugam MK, Rajendran P, Li F, Kim C, Sikka S, Siveen KS, Kumar AP, Ahn KS, Sethi G.
    Mol Carcinog; 2015 Oct 28; 54(10):971-85. PubMed ID: 24797723
    [Abstract] [Full Text] [Related]

  • 10. Arctigenin enhances chemosensitivity of cancer cells to cisplatin through inhibition of the STAT3 signaling pathway.
    Yao X, Zhu F, Zhao Z, Liu C, Luo L, Yin Z.
    J Cell Biochem; 2011 Oct 28; 112(10):2837-49. PubMed ID: 21608020
    [Abstract] [Full Text] [Related]

  • 11. Suppression of EGFR/STAT3 activity by lupeol contributes to the induction of the apoptosis of human non‑small cell lung cancer cells.
    Min TR, Park HJ, Ha KT, Chi GY, Choi YH, Park SH.
    Int J Oncol; 2019 Jul 28; 55(1):320-330. PubMed ID: 31115519
    [Abstract] [Full Text] [Related]

  • 12. γ-Tocotrienol but not γ-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents.
    Kannappan R, Yadav VR, Aggarwal BB.
    J Biol Chem; 2010 Oct 22; 285(43):33520-33529. PubMed ID: 20720018
    [Abstract] [Full Text] [Related]

  • 13. Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3.
    Dai X, Ahn KS, Kim C, Siveen KS, Ong TH, Shanmugam MK, Li F, Shi J, Kumar AP, Wang LZ, Goh BC, Magae J, Hui KM, Sethi G.
    Mol Oncol; 2015 Apr 22; 9(4):818-33. PubMed ID: 25624051
    [Abstract] [Full Text] [Related]

  • 14. A pumpkin polysaccharide induces apoptosis by inhibiting the JAK2/STAT3 pathway in human hepatoma HepG2 cells.
    Shen W, Chen C, Guan Y, Song X, Jin Y, Wang J, Hu Y, Xin T, Jiang Q, Zhong L.
    Int J Biol Macromol; 2017 Nov 22; 104(Pt A):681-686. PubMed ID: 28634059
    [Abstract] [Full Text] [Related]

  • 15. Betulinic acid suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase SHP-1 in human multiple myeloma cells.
    Pandey MK, Sung B, Aggarwal BB.
    Int J Cancer; 2010 Jul 15; 127(2):282-92. PubMed ID: 19937797
    [Abstract] [Full Text] [Related]

  • 16. Blockage of STAT3 Signaling Pathway by Morusin Induces Apoptosis and Inhibits Invasion in Human Pancreatic Tumor Cells.
    Kim C, Kim JH, Oh EY, Nam D, Lee SG, Lee J, Kim SH, Shim BS, Ahn KS.
    Pancreas; 2016 Mar 15; 45(3):409-19. PubMed ID: 26646273
    [Abstract] [Full Text] [Related]

  • 17. Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway.
    Li F, Rajendran P, Sethi G.
    Br J Pharmacol; 2010 Oct 15; 161(3):541-54. PubMed ID: 20880395
    [Abstract] [Full Text] [Related]

  • 18. Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells.
    Baek SH, Ko JH, Lee H, Jung J, Kong M, Lee JW, Lee J, Chinnathambi A, Zayed ME, Alharbi SA, Lee SG, Shim BS, Sethi G, Kim SH, Yang WM, Um JY, Ahn KS.
    Phytomedicine; 2016 May 15; 23(5):566-77. PubMed ID: 27064016
    [Abstract] [Full Text] [Related]

  • 19. Gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosis.
    Prasad S, Pandey MK, Yadav VR, Aggarwal BB.
    Cancer Prev Res (Phila); 2011 Jul 15; 4(7):1084-94. PubMed ID: 21490133
    [Abstract] [Full Text] [Related]

  • 20. Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo.
    Mohan CD, Bharathkumar H, Bulusu KC, Pandey V, Rangappa S, Fuchs JE, Shanmugam MK, Dai X, Li F, Deivasigamani A, Hui KM, Kumar AP, Lobie PE, Bender A, Basappa, Sethi G, Rangappa KS.
    J Biol Chem; 2014 Dec 05; 289(49):34296-307. PubMed ID: 25320076
    [Abstract] [Full Text] [Related]

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