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Journal Abstract Search

222 related items for PubMed ID: 25105924

  • 1. Design, synthesis and biological evaluation of 17-arylmethylamine-17-demethoxygeldanamycin derivatives as potent Hsp90 inhibitors.
    Li Z, Jia L, Wang J, Wu X, Hao H, Xu H, Wu Y, Shi G, Lu C, Shen Y.
    Eur J Med Chem; 2014 Oct 06; 85():359-70. PubMed ID: 25105924
    [Abstract] [Full Text] [Related]

  • 2. Discovery of novel 17-phenylethylaminegeldanamycin derivatives as potent Hsp90 inhibitors.
    Li Z, Jia L, Wang J, Wu X, Shi G, Lu C, Shen Y.
    Chem Biol Drug Des; 2015 Feb 06; 85(2):181-8. PubMed ID: 24903735
    [Abstract] [Full Text] [Related]

  • 3. Discovery of diamine-linked 17-aroylamido-17-demethoxygeldanamycins as potent Hsp90 inhibitors.
    Li Z, Jia L, Wang J, Wu X, Hao H, Wu Y, Xu H, Wang Z, Shi G, Lu C, Shen Y.
    Eur J Med Chem; 2014 Nov 24; 87():346-63. PubMed ID: 25277067
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of geldanamycin analogs against human cancer cells.
    Li YP, Chen JJ, Shen JJ, Cui J, Wu LZ, Wang Z, Li ZR.
    Cancer Chemother Pharmacol; 2015 Apr 24; 75(4):773-82. PubMed ID: 25681003
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  • 5. In vitro and in vivo Evaluation of 17-phenylpropylamine/phenoxyethylamine- 17-demethoxygeldanamycins as Potent Hsp90 Inhibitors.
    Li Z, Jia L, Xu H, Lu C, Shena Y.
    Med Chem; 2015 Apr 24; 11(5):482-8. PubMed ID: 25537129
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  • 7. Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90.
    Ge J, Normant E, Porter JR, Ali JA, Dembski MS, Gao Y, Georges AT, Grenier L, Pak RH, Patterson J, Sydor JR, Tibbitts TT, Tong JK, Adams J, Palombella VJ.
    J Med Chem; 2006 Jul 27; 49(15):4606-15. PubMed ID: 16854066
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  • 8. Potent cytotoxic C-11 modified geldanamycin analogues.
    Tian ZQ, Wang Z, MacMillan KS, Zhou Y, Carreras CW, Mueller T, Myles DC, Liu Y.
    J Med Chem; 2009 May 28; 52(10):3265-73. PubMed ID: 19405528
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  • 9. Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90.
    Sydor JR, Normant E, Pien CS, Porter JR, Ge J, Grenier L, Pak RH, Ali JA, Dembski MS, Hudak J, Patterson J, Penders C, Pink M, Read MA, Sang J, Woodward C, Zhang Y, Grayzel DS, Wright J, Barrett JA, Palombella VJ, Adams J, Tong JK.
    Proc Natl Acad Sci U S A; 2006 Nov 14; 103(46):17408-13. PubMed ID: 17090671
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  • 11. [Anticancer effect of 17-(6-cinnamamido-hexylamino-)-17-demethoxygeldanamycin: in vitro and in vivo].
    Li L, Liu H, Zhang SH, Hu L, Zhen YS.
    Yao Xue Xue Bao; 2013 Dec 14; 48(12):1771-7. PubMed ID: 24689233
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  • 14. Design, synthesis, and structure--activity relationships for chimeric inhibitors of Hsp90.
    Shen G, Wang M, Welch TR, Blagg BS.
    J Org Chem; 2006 Sep 29; 71(20):7618-31. PubMed ID: 16995666
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  • 16. 17-AAG and 17-DMAG-induced inhibition of cell proliferation through B-Raf downregulation in WT B-Raf-expressing uveal melanoma cell lines.
    Babchia N, Calipel A, Mouriaux F, Faussat AM, Mascarelli F.
    Invest Ophthalmol Vis Sci; 2008 Jun 29; 49(6):2348-56. PubMed ID: 18281615
    [Abstract] [Full Text] [Related]

  • 17. Macrocyclic lactams as potent Hsp90 inhibitors with excellent tumor exposure and extended biomarker activity.
    Zapf CW, Bloom JD, McBean JL, Dushin RG, Nittoli T, Otteng M, Ingalls C, Golas JM, Liu H, Lucas J, Boschelli F, Hu Y, Vogan E, Levin JI.
    Bioorg Med Chem Lett; 2011 Jun 01; 21(11):3411-6. PubMed ID: 21515049
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  • 18. Synthesis and biological evaluation of heat-shock protein 90 inhibitors: geldanamycin derivatives with broad antiviral activities.
    Li YP, Shan GZ, Peng ZG, Zhu JH, Meng S, Zhang T, Gao LY, Tao PZ, Gao RM, Li YH, Jiang JD, Li ZR.
    Antivir Chem Chemother; 2010 Aug 11; 20(6):259-68. PubMed ID: 20710066
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  • 20. Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo.
    Schwock J, Pham NA, Cao MP, Hedley DW.
    Cancer Chemother Pharmacol; 2008 Apr 11; 61(4):669-81. PubMed ID: 17579866
    [Abstract] [Full Text] [Related]

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