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Journal Abstract Search

171 related items for PubMed ID: 25124033

  • 1. Degradation of Tiam1 by casein kinase 1 and the SCFβTrCP ubiquitin ligase controls the duration of mTOR-S6K signaling.
    Magliozzi R, Kim J, Low TY, Heck AJ, Guardavaccaro D.
    J Biol Chem; 2014 Oct 03; 289(40):27400-9. PubMed ID: 25124033
    [Abstract] [Full Text] [Related]

  • 2. DEPTOR, an mTOR inhibitor, is a physiological substrate of SCF(βTrCP) E3 ubiquitin ligase and regulates survival and autophagy.
    Zhao Y, Xiong X, Sun Y.
    Mol Cell; 2011 Oct 21; 44(2):304-16. PubMed ID: 22017876
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  • 3. DNA damage induces the accumulation of Tiam1 by blocking β-TrCP-dependent degradation.
    Zhu G, Fan Z, Ding M, Mu L, Liang J, Ding Y, Fu Y, Huang B, Wu W.
    J Biol Chem; 2014 May 30; 289(22):15482-94. PubMed ID: 24737324
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  • 4. mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR.
    Duan S, Skaar JR, Kuchay S, Toschi A, Kanarek N, Ben-Neriah Y, Pagano M.
    Mol Cell; 2011 Oct 21; 44(2):317-24. PubMed ID: 22017877
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  • 5. A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.
    Low TY, Peng M, Magliozzi R, Mohammed S, Guardavaccaro D, Heck AJ.
    Sci Signal; 2014 Dec 16; 7(356):rs8. PubMed ID: 25515538
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  • 7. Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin.
    Buchsbaum RJ, Connolly BA, Feig LA.
    J Biol Chem; 2003 May 23; 278(21):18833-41. PubMed ID: 12531897
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  • 8. E3 Ligase SCFβTrCP-induced DYRK1A Protein Degradation Is Essential for Cell Cycle Progression in HEK293 Cells.
    Liu Q, Tang Y, Chen L, Liu N, Lang F, Liu H, Wang P, Sun X.
    J Biol Chem; 2016 Dec 16; 291(51):26399-26409. PubMed ID: 27807027
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  • 9. S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth.
    Dorrello NV, Peschiaroli A, Guardavaccaro D, Colburn NH, Sherman NE, Pagano M.
    Science; 2006 Oct 20; 314(5798):467-71. PubMed ID: 17053147
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  • 11. HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion.
    Vaughan L, Tan CT, Chapman A, Nonaka D, Mack NA, Smith D, Booton R, Hurlstone AF, Malliri A.
    Cell Rep; 2015 Jan 06; 10(1):88-102. PubMed ID: 25543140
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  • 12. Proteasomal degradation of eukaryotic elongation factor-2 kinase (EF2K) is regulated by cAMP-PKA signaling and the SCFβTRCP ubiquitin E3 ligase.
    Wiseman SL, Shimizu Y, Palfrey C, Nairn AC.
    J Biol Chem; 2013 Jun 14; 288(24):17803-11. PubMed ID: 23640883
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  • 13. Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling.
    Scheufele F, Wolf B, Kruse M, Hartmann T, Lempart J, Mühlich S, Pfeiffer AFH, Field LJ, Charron MJ, Pan ZQ, Engelhardt S, Sarikas A.
    Cell Signal; 2014 Feb 14; 26(2):233-239. PubMed ID: 24219910
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  • 15. Skp1-Cul1-F-box ubiquitin ligase (SCF(βTrCP))-mediated destruction of the ubiquitin-specific protease USP37 during G2-phase promotes mitotic entry.
    Burrows AC, Prokop J, Summers MK.
    J Biol Chem; 2012 Nov 09; 287(46):39021-9. PubMed ID: 23027877
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