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1801 related items for PubMed ID: 25128467

  • 1. FoxO proteins' nuclear retention and BH3-only protein Bim induction evoke mitochondrial dysfunction-mediated apoptosis in berberine-treated HepG2 cells.
    Shukla S, Rizvi F, Raisuddin S, Kakkar P.
    Free Radic Biol Med; 2014 Nov; 76():185-99. PubMed ID: 25128467
    [Abstract] [Full Text] [Related]

  • 2. Concurrent acetylation of FoxO1/3a and p53 due to sirtuins inhibition elicit Bim/PUMA mediated mitochondrial dysfunction and apoptosis in berberine-treated HepG2 cells.
    Shukla S, Sharma A, Pandey VK, Raisuddin S, Kakkar P.
    Toxicol Appl Pharmacol; 2016 Jan 15; 291():70-83. PubMed ID: 26712469
    [Abstract] [Full Text] [Related]

  • 3. 18β-glycyrrhetinic acid induces apoptosis through modulation of Akt/FOXO3a/Bim pathway in human breast cancer MCF-7 cells.
    Sharma G, Kar S, Palit S, Das PK.
    J Cell Physiol; 2012 May 15; 227(5):1923-31. PubMed ID: 21732363
    [Abstract] [Full Text] [Related]

  • 4. Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway.
    Boreddy SR, Pramanik KC, Srivastava SK.
    Clin Cancer Res; 2011 Apr 01; 17(7):1784-95. PubMed ID: 21350002
    [Abstract] [Full Text] [Related]

  • 5. Insulin receptor substrate-1 and -2 mediate resistance to glucose-induced caspase-3 activation in human neuroblastoma cells.
    Stöhr O, Hahn J, Moll L, Leeser U, Freude S, Bernard C, Schilbach K, Markl A, Udelhoven M, Krone W, Schubert M.
    Biochim Biophys Acta; 2011 May 01; 1812(5):573-80. PubMed ID: 21354306
    [Abstract] [Full Text] [Related]

  • 6. FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells.
    Obexer P, Geiger K, Ambros PF, Meister B, Ausserlechner MJ.
    Cell Death Differ; 2007 Mar 01; 14(3):534-47. PubMed ID: 16888645
    [Abstract] [Full Text] [Related]

  • 7. Berberine induced modulation of PHLPP2-Akt-MST1 kinase signaling is coupled with mitochondrial impairment and hepatoma cell death.
    Saxena S, Shukla S, Kakkar P.
    Toxicol Appl Pharmacol; 2018 May 15; 347():92-103. PubMed ID: 29626488
    [Abstract] [Full Text] [Related]

  • 8. FOXO3-mediated up-regulation of Bim contributes to rhein-induced cancer cell apoptosis.
    Wang J, Liu S, Yin Y, Li M, Wang B, Yang L, Jiang Y.
    Apoptosis; 2015 Mar 15; 20(3):399-409. PubMed ID: 25501496
    [Abstract] [Full Text] [Related]

  • 9. Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells.
    Carbajo-Pescador S, Steinmetz C, Kashyap A, Lorenz S, Mauriz JL, Heise M, Galle PR, González-Gallego J, Strand S.
    Br J Cancer; 2013 Feb 05; 108(2):442-9. PubMed ID: 23257900
    [Abstract] [Full Text] [Related]

  • 10. MicroRNA-21 plays an oncogenic role by targeting FOXO1 and activating the PI3K/AKT pathway in diffuse large B-cell lymphoma.
    Go H, Jang JY, Kim PJ, Kim YG, Nam SJ, Paik JH, Kim TM, Heo DS, Kim CW, Jeon YK.
    Oncotarget; 2015 Jun 20; 6(17):15035-49. PubMed ID: 25909227
    [Abstract] [Full Text] [Related]

  • 11. The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms.
    Paraiso KH, Haarberg HE, Wood E, Rebecca VW, Chen YA, Xiang Y, Ribas A, Lo RS, Weber JS, Sondak VK, John JK, Sarnaik AA, Koomen JM, Smalley KS.
    Clin Cancer Res; 2012 May 01; 18(9):2502-14. PubMed ID: 22351686
    [Abstract] [Full Text] [Related]

  • 12. Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells.
    Guan H, Song L, Cai J, Huang Y, Wu J, Yuan J, Li J, Li M.
    PLoS One; 2011 May 01; 6(5):e19946. PubMed ID: 21625639
    [Abstract] [Full Text] [Related]

  • 13. Resveratrol induces apoptosis through modulation of the Akt/FoxO3a/Bim pathway in HepG2 cells.
    Liu MH, Lin XL, Li J, He J, Tan TP, Wu SJ, Yu S, Chen L, Liu J, Tian W, Chen YD, Fu HY, Yuan C, Zhang Y.
    Mol Med Rep; 2016 Feb 01; 13(2):1689-94. PubMed ID: 26709007
    [Abstract] [Full Text] [Related]

  • 14. Apigenin inhibits prostate cancer progression in TRAMP mice via targeting PI3K/Akt/FoxO pathway.
    Shukla S, Bhaskaran N, Babcook MA, Fu P, Maclennan GT, Gupta S.
    Carcinogenesis; 2014 Feb 01; 35(2):452-60. PubMed ID: 24067903
    [Abstract] [Full Text] [Related]

  • 15. FOXO3a mediates the cytotoxic effects of cisplatin in lung cancer cells.
    Liu H, Yin J, Wang C, Gu Y, Deng M, He Z.
    Anticancer Drugs; 2014 Sep 01; 25(8):898-907. PubMed ID: 24814195
    [Abstract] [Full Text] [Related]

  • 16. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
    Rahmani M, Aust MM, Attkisson E, Williams DC, Ferreira-Gonzalez A, Grant S.
    Cancer Res; 2013 Feb 15; 73(4):1340-51. PubMed ID: 23243017
    [Abstract] [Full Text] [Related]

  • 17. CHIP regulates AKT/FoxO/Bim signaling in MCF7 and MCF10A cells.
    Lv Y, Song S, Zhang K, Gao H, Ma R.
    PLoS One; 2013 Feb 15; 8(12):e83312. PubMed ID: 24376685
    [Abstract] [Full Text] [Related]

  • 18. FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity.
    Dijkers PF, Birkenkamp KU, Lam EW, Thomas NS, Lammers JW, Koenderman L, Coffer PJ.
    J Cell Biol; 2002 Feb 04; 156(3):531-42. PubMed ID: 11815629
    [Abstract] [Full Text] [Related]

  • 19. Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo.
    Shao H, Gao C, Tang H, Zhang H, Roberts LR, Hylander BL, Repasky EA, Ma WW, Qiu J, Adjei AA, Dy GK, Yu C.
    J Hepatol; 2012 Jan 04; 56(1):176-83. PubMed ID: 21835141
    [Abstract] [Full Text] [Related]

  • 20. Activation of FoxO3a/Bim axis in patients with Primary Biliary Cirrhosis.
    Kopycinska J, Kempińska-Podhorodecka A, Haas T, Elias E, DePinho RA, Paik J, Milkiewicz P, Milkiewicz M.
    Liver Int; 2013 Feb 04; 33(2):231-8. PubMed ID: 23295054
    [Abstract] [Full Text] [Related]

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