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Journal Abstract Search

375 related items for PubMed ID: 25169971

  • 1. Attenuated development of cardiac fibrosis in left ventricular pressure overload by SM16, an orally active inhibitor of ALK5.
    Engebretsen KV, Skårdal K, Bjørnstad S, Marstein HS, Skrbic B, Sjaastad I, Christensen G, Bjørnstad JL, Tønnessen T.
    J Mol Cell Cardiol; 2014 Nov; 76():148-57. PubMed ID: 25169971
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of SMAD2 phosphorylation preserves cardiac function during pressure overload.
    Bjørnstad JL, Skrbic B, Marstein HS, Hasic A, Sjaastad I, Louch WE, Florholmen G, Christensen G, Tønnessen T.
    Cardiovasc Res; 2012 Jan 01; 93(1):100-10. PubMed ID: 22049534
    [Abstract] [Full Text] [Related]

  • 3. SM16, an orally active TGF-beta type I receptor inhibitor prevents myofibroblast induction and vascular fibrosis in the rat carotid injury model.
    Fu K, Corbley MJ, Sun L, Friedman JE, Shan F, Papadatos JL, Costa D, Lutterodt F, Sweigard H, Bowes S, Choi M, Boriack-Sjodin PA, Arduini RM, Sun D, Newman MN, Zhang X, Mead JN, Chuaqui CE, Cheung HK, Zhang X, Cornebise M, Carter MB, Josiah S, Singh J, Lee WC, Gill A, Ling LE.
    Arterioscler Thromb Vasc Biol; 2008 Apr 01; 28(4):665-71. PubMed ID: 18202322
    [Abstract] [Full Text] [Related]

  • 4. An orally active small molecule TGF-beta receptor I antagonist inhibits the growth of metastatic murine breast cancer.
    Rausch MP, Hahn T, Ramanathapuram L, Bradley-Dunlop D, Mahadevan D, Mercado-Pimentel ME, Runyan RB, Besselsen DG, Zhang X, Cheung HK, Lee WC, Ling LE, Akporiaye ET.
    Anticancer Res; 2009 Jun 01; 29(6):2099-109. PubMed ID: 19528470
    [Abstract] [Full Text] [Related]

  • 5. Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice.
    Skrbic B, Engebretsen KV, Strand ME, Lunde IG, Herum KM, Marstein HS, Sjaastad I, Lunde PK, Carlson CR, Christensen G, Bjørnstad JL, Tønnessen T.
    Cardiovasc Res; 2015 Apr 01; 106(1):32-42. PubMed ID: 25694587
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  • 9. MicroRNA-101a suppresses fibrotic programming in isolated cardiac fibroblasts and in vivo fibrosis following trans-aortic constriction.
    Zhou Y, Shiok TC, Richards AM, Wang P.
    J Mol Cell Cardiol; 2018 Aug 01; 121():266-276. PubMed ID: 30053527
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  • 11. The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload.
    Mohammadzadeh N, Lunde IG, Andenæs K, Strand ME, Aronsen JM, Skrbic B, Marstein HS, Bandlien C, Nygård S, Gorham J, Sjaastad I, Chakravarti S, Christensen G, Engebretsen KVT, Tønnessen T.
    Sci Rep; 2019 Jun 24; 9(1):9206. PubMed ID: 31235849
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  • 12. Transforming growth factor (TGF)-β type I receptor kinase (ALK5) inhibitor alleviates profibrotic TGF-β1 responses in fibroblasts derived from Peyronie's plaque.
    Piao S, Choi MJ, Tumurbaatar M, Kim WJ, Jin HR, Shin SH, Tuvshintur B, Yin GN, Song JS, Kwon MH, Lee SJ, Han JY, Kim SJ, Ryu JK, Suh JK.
    J Sex Med; 2010 Oct 24; 7(10):3385-95. PubMed ID: 20233292
    [Abstract] [Full Text] [Related]

  • 13. BMP-7 attenuates left ventricular remodelling under pressure overload and facilitates reverse remodelling and functional recovery.
    Merino D, Villar AV, García R, Tramullas M, Ruiz L, Ribas C, Cabezudo S, Nistal JF, Hurlé MA.
    Cardiovasc Res; 2016 Jun 01; 110(3):331-45. PubMed ID: 27068510
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  • 14. Fibroblast-specific TGF-β-Smad2/3 signaling underlies cardiac fibrosis.
    Khalil H, Kanisicak O, Prasad V, Correll RN, Fu X, Schips T, Vagnozzi RJ, Liu R, Huynh T, Lee SJ, Karch J, Molkentin JD.
    J Clin Invest; 2017 Oct 02; 127(10):3770-3783. PubMed ID: 28891814
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  • 15. MicroRNA-221/222 Family Counteracts Myocardial Fibrosis in Pressure Overload-Induced Heart Failure.
    Verjans R, Peters T, Beaumont FJ, van Leeuwen R, van Herwaarden T, Verhesen W, Munts C, Bijnen M, Henkens M, Diez J, de Windt LJ, van Nieuwenhoven FA, van Bilsen M, Goumans MJ, Heymans S, González A, Schroen B.
    Hypertension; 2018 Feb 02; 71(2):280-288. PubMed ID: 29255073
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  • 16. Qishen granule attenuates cardiac fibrosis by regulating TGF-β /Smad3 and GSK-3β pathway.
    Zeng Z, Wang Q, Yang X, Ren Y, Jiao S, Zhu Q, Guo D, Xia K, Wang Y, Li C, Wang W.
    Phytomedicine; 2019 Sep 02; 62():152949. PubMed ID: 31102891
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  • 17. Sirtuin 1 activation attenuates cardiac fibrosis in a rodent pressure overload model by modifying Smad2/3 transactivation.
    Bugyei-Twum A, Ford C, Civitarese R, Seegobin J, Advani SL, Desjardins JF, Kabir G, Zhang Y, Mitchell M, Switzer J, Thai K, Shen V, Abadeh A, Singh KK, Billia F, Advani A, Gilbert RE, Connelly KA.
    Cardiovasc Res; 2018 Oct 01; 114(12):1629-1641. PubMed ID: 29800064
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  • 18. Metformin attenuates cardiac fibrosis by inhibiting the TGFbeta1-Smad3 signalling pathway.
    Xiao H, Ma X, Feng W, Fu Y, Lu Z, Xu M, Shen Q, Zhu Y, Zhang Y.
    Cardiovasc Res; 2010 Aug 01; 87(3):504-13. PubMed ID: 20200042
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  • 19. Identification of TGF-β receptor-1 as a key regulator of carbon nanotube-induced fibrogenesis.
    Mishra A, Stueckle TA, Mercer RR, Derk R, Rojanasakul Y, Castranova V, Wang L.
    Am J Physiol Lung Cell Mol Physiol; 2015 Oct 15; 309(8):L821-33. PubMed ID: 26472812
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  • 20. Soluble transforming growth factor-beta1 receptor II might inhibit transforming growth factor-beta-induced myofibroblast differentiation and improve ischemic cardiac function after myocardial infarction in rats.
    Lian R, Chen Y, Xu Z, Zhang X.
    Coron Artery Dis; 2010 Sep 15; 21(6):369-77. PubMed ID: 20613497
    [Abstract] [Full Text] [Related]

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