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Journal Abstract Search


415 related items for PubMed ID: 25179574

  • 1. Inhibitory effects of AG490 on H2O2-induced TRPM2-mediated Ca(2+) entry.
    Shimizu S, Yonezawa R, Hagiwara T, Yoshida T, Takahashi N, Hamano S, Negoro T, Toda T, Wakamori M, Mori Y, Ishii M.
    Eur J Pharmacol; 2014 Nov 05; 742():22-30. PubMed ID: 25179574
    [Abstract] [Full Text] [Related]

  • 2. Sensitization of H2O2-induced TRPM2 activation and subsequent interleukin-8 (CXCL8) production by intracellular Fe(2+) in human monocytic U937 cells.
    Shimizu S, Yonezawa R, Negoro T, Yamamoto S, Numata T, Ishii M, Mori Y, Toda T.
    Int J Biochem Cell Biol; 2015 Nov 05; 68():119-27. PubMed ID: 26386353
    [Abstract] [Full Text] [Related]

  • 3. Inhibitory effects of Tyrphostin AG-related compounds on oxidative stress-sensitive transient receptor potential channel activation.
    Toda T, Yamamoto S, Yonezawa R, Mori Y, Shimizu S.
    Eur J Pharmacol; 2016 Sep 05; 786():19-28. PubMed ID: 27238971
    [Abstract] [Full Text] [Related]

  • 4. TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase.
    Fonfria E, Marshall IC, Benham CD, Boyfield I, Brown JD, Hill K, Hughes JP, Skaper SD, McNulty S.
    Br J Pharmacol; 2004 Sep 05; 143(1):186-92. PubMed ID: 15302683
    [Abstract] [Full Text] [Related]

  • 5. Tyrphostin AG-related compounds attenuate H2O2-induced TRPM2-dependent and -independent cellular responses.
    Yamamoto S, Toda T, Yonezawa R, Negoro T, Shimizu S.
    J Pharmacol Sci; 2017 May 05; 134(1):68-74. PubMed ID: 28532624
    [Abstract] [Full Text] [Related]

  • 6. TNF-α-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes.
    Roberge S, Roussel J, Andersson DC, Meli AC, Vidal B, Blandel F, Lanner JT, Le Guennec JY, Katz A, Westerblad H, Lacampagne A, Fauconnier J.
    Cardiovasc Res; 2014 Jul 01; 103(1):90-9. PubMed ID: 24802330
    [Abstract] [Full Text] [Related]

  • 7. Role of TRPM2 channel in mediating H2O2-induced Ca2+ entry and endothelial hyperpermeability.
    Hecquet CM, Ahmmed GU, Vogel SM, Malik AB.
    Circ Res; 2008 Feb 15; 102(3):347-55. PubMed ID: 18048770
    [Abstract] [Full Text] [Related]

  • 8. Intracellular-produced hydroxyl radical mediates H2O2-induced Ca2+ influx and cell death in rat beta-cell line RIN-5F.
    Ishii M, Shimizu S, Hara Y, Hagiwara T, Miyazaki A, Mori Y, Kiuchi Y.
    Cell Calcium; 2006 Jun 15; 39(6):487-94. PubMed ID: 16546253
    [Abstract] [Full Text] [Related]

  • 9. Activation of TRPM2 and TRPV1 Channels in Dorsal Root Ganglion by NADPH Oxidase and Protein Kinase C Molecular Pathways: a Patch Clamp Study.
    Nazıroğlu M.
    J Mol Neurosci; 2017 Mar 15; 61(3):425-435. PubMed ID: 28097492
    [Abstract] [Full Text] [Related]

  • 10. The Protective Role of Selenium on Scopolamine-Induced Memory Impairment, Oxidative Stress, and Apoptosis in Aged Rats: The Involvement of TRPM2 and TRPV1 Channels.
    Balaban H, Nazıroğlu M, Demirci K, Övey İS.
    Mol Neurobiol; 2017 May 15; 54(4):2852-2868. PubMed ID: 27021021
    [Abstract] [Full Text] [Related]

  • 11. Hypericum perforatum Attenuates Spinal Cord Injury-Induced Oxidative Stress and Apoptosis in the Dorsal Root Ganglion of Rats: Involvement of TRPM2 and TRPV1 Channels.
    Özdemir ÜS, Nazıroğlu M, Şenol N, Ghazizadeh V.
    Mol Neurobiol; 2016 Aug 15; 53(6):3540-3551. PubMed ID: 26099309
    [Abstract] [Full Text] [Related]

  • 12. TRPM2 channels in alveolar epithelial cells mediate bleomycin-induced lung inflammation.
    Yonezawa R, Yamamoto S, Takenaka M, Kage Y, Negoro T, Toda T, Ohbayashi M, Numata T, Nakano Y, Yamamoto T, Mori Y, Ishii M, Shimizu S.
    Free Radic Biol Med; 2016 Jan 15; 90():101-13. PubMed ID: 26600069
    [Abstract] [Full Text] [Related]

  • 13. Signalling mechanisms mediating Zn2+-induced TRPM2 channel activation and cell death in microglial cells.
    Mortadza SS, Sim JA, Stacey M, Jiang LH.
    Sci Rep; 2017 Mar 21; 7():45032. PubMed ID: 28322340
    [Abstract] [Full Text] [Related]

  • 14. New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose.
    Naziroğlu M.
    Neurochem Res; 2007 Nov 21; 32(11):1990-2001. PubMed ID: 17562166
    [Abstract] [Full Text] [Related]

  • 15. Duloxetine Reduces Oxidative Stress, Apoptosis, and Ca2+ Entry Through Modulation of TRPM2 and TRPV1 Channels in the Hippocampus and Dorsal Root Ganglion of Rats.
    Demirdaş A, Nazıroğlu M, Övey İS.
    Mol Neurobiol; 2017 Aug 21; 54(6):4683-4695. PubMed ID: 27443158
    [Abstract] [Full Text] [Related]

  • 16. Crosstalk Between Vascular Redox and Calcium Signaling in Hypertension Involves TRPM2 (Transient Receptor Potential Melastatin 2) Cation Channel.
    Alves-Lopes R, Neves KB, Anagnostopoulou A, Rios FJ, Lacchini S, Montezano AC, Touyz RM.
    Hypertension; 2020 Jan 21; 75(1):139-149. PubMed ID: 31735084
    [Abstract] [Full Text] [Related]

  • 17. Free fatty acid-induced H2O2 activates TRPM2 to aggravate endothelial insulin resistance via Ca2+-dependent PERK/ATF4/TRB3 cascade in obese mice.
    Sun L, Liu YL, Ye F, Xie JW, Zeng JW, Qin L, Xue J, Wang YT, Guo KM, Ma MM, Tang YB, Li XY, Gao M.
    Free Radic Biol Med; 2019 Nov 01; 143():288-299. PubMed ID: 31445205
    [Abstract] [Full Text] [Related]

  • 18. A critical role of the transient receptor potential melastatin 2 channel in a positive feedback mechanism for reactive oxygen species-induced delayed cell death.
    Li X, Jiang LH.
    J Cell Physiol; 2019 Apr 01; 234(4):3647-3660. PubMed ID: 30229906
    [Abstract] [Full Text] [Related]

  • 19. TRPM2 channel protective properties of N-acetylcysteine on cytosolic glutathione depletion dependent oxidative stress and Ca2+ influx in rat dorsal root ganglion.
    Özgül C, Nazıroğlu M.
    Physiol Behav; 2012 May 15; 106(2):122-8. PubMed ID: 22300897
    [Abstract] [Full Text] [Related]

  • 20. Exposure of glia to pro-oxidant agents revealed selective Stat1 activation by H2O2 and Jak2-independent antioxidant features of the Jak2 inhibitor AG490.
    Gorina R, Sanfeliu C, Galitó A, Messeguer A, Planas AM.
    Glia; 2007 Oct 15; 55(13):1313-24. PubMed ID: 17607690
    [Abstract] [Full Text] [Related]


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