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326 related items for PubMed ID: 25179905

  • 1. Tumor suppressor protein p53 promotes 2-methoxyestradiol-induced activation of Bak and Bax, leading to mitochondria-dependent apoptosis in human colon cancer HCT116 cells.
    Lee JY, Jee SB, Park WY, Choi YJ, Kim B, Kim YH, Jun do Y, Kim YH.
    J Microbiol Biotechnol; 2014 Dec 28; 24(12):1654-63. PubMed ID: 25179905
    [Abstract] [Full Text] [Related]

  • 2. Dependency of 2-methoxyestradiol-induced mitochondrial apoptosis on mitotic spindle network impairment and prometaphase arrest in human Jurkat T cells.
    Lee ST, Lee JY, Han CR, Kim YH, Jun do Y, Taub D, Kim YH.
    Biochem Pharmacol; 2015 Apr 15; 94(4):257-69. PubMed ID: 25732194
    [Abstract] [Full Text] [Related]

  • 3. Prometaphase arrest-dependent phosphorylation of Bcl-2 family proteins and activation of mitochondrial apoptotic pathway are associated with 17α-estradiol-induced apoptosis in human Jurkat T cells.
    Han CR, Jun do Y, Kim YH, Lee JY, Kim YH.
    Biochim Biophys Acta; 2013 Oct 15; 1833(10):2220-32. PubMed ID: 23707954
    [Abstract] [Full Text] [Related]

  • 4. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J, Huang K, O'Neill KL, Pang X, Luo X.
    Cell Death Dis; 2016 Jun 16; 7(6):e2266. PubMed ID: 27310874
    [Abstract] [Full Text] [Related]

  • 5. Prometaphase arrest-dependent phosphorylation of Bcl-2 and Bim reduces the association of Bcl-2 with Bak or Bim, provoking Bak activation and mitochondrial apoptosis in nocodazole-treated Jurkat T cells.
    Han CR, Jun do Y, Lee JY, Kim YH.
    Apoptosis; 2014 Jan 16; 19(1):224-40. PubMed ID: 24166139
    [Abstract] [Full Text] [Related]

  • 6. Cytoprotective effect of 2-carbomethoxy-2,3-epoxy-3-prenyl-1,4-naphthoquinone (CMEP-NQ) is mediated by the inhibition of BAK-dependent mitochondrial apoptosis pathway.
    Jun DY, Jang WY, Kim KY, Woo MH, Kim YH.
    PLoS One; 2018 Jan 16; 13(10):e0204585. PubMed ID: 30273361
    [Abstract] [Full Text] [Related]

  • 7. Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells.
    Hemmati PG, Güner D, Gillissen B, Wendt J, von Haefen C, Chinnadurai G, Dörken B, Daniel PT.
    Oncogene; 2006 Oct 26; 25(50):6582-94. PubMed ID: 16847458
    [Abstract] [Full Text] [Related]

  • 8. Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner.
    Guo W, Zhang Y, Ling Z, Liu X, Zhao X, Yuan Z, Nie C, Wei Y.
    Cell Death Dis; 2015 Oct 15; 6(10):e1919. PubMed ID: 26469967
    [Abstract] [Full Text] [Related]

  • 9. Mitochondrial p53 phosphorylation induces Bak-mediated and caspase-independent cell death.
    Wang J, Guo W, Zhou H, Luo N, Nie C, Zhao X, Yuan Z, Liu X, Wei Y.
    Oncotarget; 2015 Jul 10; 6(19):17192-205. PubMed ID: 25980443
    [Abstract] [Full Text] [Related]

  • 10. Kaempferol Activates G₂-Checkpoint of the Cell Cycle Resulting in G₂-Arrest and Mitochondria-Dependent Apoptosis in Human Acute Leukemia Jurkat T Cells.
    Kim KY, Jang WY, Lee JY, Jun do Y, Ko JY, Yun YH, Kim YH.
    J Microbiol Biotechnol; 2016 Feb 10; 26(2):287-94. PubMed ID: 26699757
    [Abstract] [Full Text] [Related]

  • 11. Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK.
    Ling YH, Lin R, Perez-Soler R.
    Mol Pharmacol; 2008 Sep 10; 74(3):793-806. PubMed ID: 18524889
    [Abstract] [Full Text] [Related]

  • 12. p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.
    Müer A, Overkamp T, Gillissen B, Richter A, Pretzsch T, Milojkovic A, Dörken B, Daniel PT, Hemmati P.
    J Biol Chem; 2012 May 18; 287(21):17343-17352. PubMed ID: 22354970
    [Abstract] [Full Text] [Related]

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  • 14. Investigation of the role of Bax, p21/Waf1 and p53 as determinants of cellular responses in HCT116 colorectal cancer cells exposed to the novel cytotoxic ruthenium(II) organometallic agent, RM175.
    Hayward RL, Schornagel QC, Tente R, Macpherson JS, Aird RE, Guichard S, Habtemariam A, Sadler P, Jodrell DI.
    Cancer Chemother Pharmacol; 2005 Jun 18; 55(6):577-83. PubMed ID: 15726367
    [Abstract] [Full Text] [Related]

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  • 16. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane.
    O'Neill KL, Huang K, Zhang J, Chen Y, Luo X.
    Genes Dev; 2016 Apr 15; 30(8):973-88. PubMed ID: 27056669
    [Abstract] [Full Text] [Related]

  • 17. Phylogenetically Distant Viruses Use the Same BH3-Only Protein Puma to Trigger Bax/Bak-Dependent Apoptosis of Infected Mouse and Human Cells.
    Papaianni E, El Maadidi S, Schejtman A, Neumann S, Maurer U, Marino-Merlo F, Mastino A, Borner C.
    PLoS One; 2015 Apr 15; 10(6):e0126645. PubMed ID: 26030884
    [Abstract] [Full Text] [Related]

  • 18. Apoptosis-induced effects of extract from Artemisia annua Linné by modulating PTEN/p53/PDK1/Akt/ signal pathways through PTEN/p53-independent manner in HCT116 colon cancer cells.
    Kim EJ, Kim GT, Kim BM, Lim EG, Kim SY, Kim YM.
    BMC Complement Altern Med; 2017 Apr 28; 17(1):236. PubMed ID: 28454566
    [Abstract] [Full Text] [Related]

  • 19. Synthetic Bichalcone TSWU-BR23 Induces Apoptosis of Human Colon Cancer HT-29 Cells by p53-Mediated Mitochondrial Oligomerization of BAX/BAK and Lipid Raft Localization of CD95/FADD.
    Lin ML, Chen SS, Wu TS.
    Anticancer Res; 2015 Oct 28; 35(10):5407-16. PubMed ID: 26408703
    [Abstract] [Full Text] [Related]

  • 20. Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells.
    Matsumoto M, Nakajima W, Seike M, Gemma A, Tanaka N.
    Biochem Biophys Res Commun; 2016 Apr 29; 473(2):490-6. PubMed ID: 26996126
    [Abstract] [Full Text] [Related]

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