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489 related items for PubMed ID: 25189691

  • 1. Synthesis and evaluation of a 18F-labeled spirocyclic piperidine derivative as promising σ1 receptor imaging agent.
    Chen YY, Wang X, Zhang JM, Deuther-Conrad W, Zhang XJ, Huang Y, Li Y, Ye JJ, Cui MC, Steinbach J, Brust P, Liu BL, Jia HM.
    Bioorg Med Chem; 2014 Oct 01; 22(19):5270-8. PubMed ID: 25189691
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and evaluation of novel (18)F-labeled spirocyclic piperidine derivatives as σ1 receptor ligands for positron emission tomography imaging.
    Li Y, Wang X, Zhang J, Deuther-Conrad W, Xie F, Zhang X, Liu J, Qiao J, Cui M, Steinbach J, Brust P, Liu B, Jia H.
    J Med Chem; 2013 May 09; 56(9):3478-91. PubMed ID: 23566245
    [Abstract] [Full Text] [Related]

  • 3. A ¹⁸F-labeled fluorobutyl-substituted spirocyclic piperidine derivative as a selective radioligand for PET Imaging of sigma₁ receptors.
    Maisonial A, Grosse Maestrup E, Fischer S, Hiller A, Scheunemann M, Wiese C, Schepmann D, Steinbach J, Deuther-Conrad W, Wünsch B, Brust P.
    ChemMedChem; 2011 Aug 01; 6(8):1401-10. PubMed ID: 21618432
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and evaluation of a (18) F-labeled 4-phenylpiperidine-4-carbonitrile radioligand for σ1 receptor imaging.
    Ye J, Wang X, Deuther-Conrad W, Zhang J, Li J, Zhang X, Wang L, Steinbach J, Brust P, Jia H.
    J Labelled Comp Radiopharm; 2016 Jul 01; 59(9):332-9. PubMed ID: 27277387
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of ¹⁸F labeled fluoro-oligo-ethoxylated 4-benzylpiperazine derivatives for sigma-1 receptor imaging.
    Wang X, Li Y, Deuther-Conrad W, Xie F, Chen X, Cui MC, Zhang XJ, Zhang JM, Steinbach J, Brust P, Liu BL, Jia HM.
    Bioorg Med Chem; 2013 Jan 01; 21(1):215-22. PubMed ID: 23199475
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and evaluation of new 1-oxa-8-azaspiro[4.5]decane derivatives as candidate radioligands for sigma-1 receptors.
    Tian J, He Y, Deuther-Conrad W, Fu H, Xie F, Zhang Y, Wang T, Zhang X, Zhang J, Brust P, Huang Y, Jia H.
    Bioorg Med Chem; 2020 Jul 15; 28(14):115560. PubMed ID: 32616183
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis, and structure-affinity relationships of regioisomeric N-benzyl alkyl ether piperazine derivatives as sigma-1 receptor ligands.
    Moussa IA, Banister SD, Beinat C, Giboureau N, Reynolds AJ, Kassiou M.
    J Med Chem; 2010 Aug 26; 53(16):6228-39. PubMed ID: 20662542
    [Abstract] [Full Text] [Related]

  • 8. Molecular imaging of σ receptors: synthesis and evaluation of the potent σ1 selective radioligand [18F]fluspidine.
    Fischer S, Wiese C, Maestrup EG, Hiller A, Deuther-Conrad W, Scheunemann M, Schepmann D, Steinbach J, Wünsch B, Brust P.
    Eur J Nucl Med Mol Imaging; 2011 Mar 26; 38(3):540-51. PubMed ID: 21072511
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and quantitative structure-activity relationships of N-(1-benzylpiperidin-4-yl)phenylacetamides and related analogues as potent and selective sigma1 receptor ligands.
    Huang Y, Hammond PS, Whirrett BR, Kuhner RJ, Wu L, Childers SR, Mach RH.
    J Med Chem; 1998 Jun 18; 41(13):2361-70. PubMed ID: 9632369
    [Abstract] [Full Text] [Related]

  • 10. 18 F-Labeled benzylpiperazine derivatives as highly selective ligands for imaging σ1 receptor with positron emission tomography.
    Ye J, Wang L, Deuther-Conrad W, Chen Y, Zhang X, Zhang J, Huang Y, Brust P, Jia H.
    J Labelled Comp Radiopharm; 2019 Jun 30; 62(8):425-437. PubMed ID: 30991462
    [Abstract] [Full Text] [Related]

  • 11. (18)F-Labeled 1,4-Dioxa-8-azaspiro[4.5]decane Derivative: Synthesis and Biological Evaluation of a σ1 Receptor Radioligand with Low Lipophilicity as Potent Tumor Imaging Agent.
    Xie F, Bergmann R, Kniess T, Deuther-Conrad W, Mamat C, Neuber C, Liu B, Steinbach J, Brust P, Pietzsch J, Jia H.
    J Med Chem; 2015 Jul 23; 58(14):5395-407. PubMed ID: 26090686
    [Abstract] [Full Text] [Related]

  • 12. Radiosynthesis and preclinical evaluation of 18F-F13714 as a fluorinated 5-HT1A receptor agonist radioligand for PET neuroimaging.
    Lemoine L, Becker G, Vacher B, Billard T, Lancelot S, Newman-Tancredi A, Zimmer L.
    J Nucl Med; 2012 Jun 23; 53(6):969-76. PubMed ID: 22577236
    [Abstract] [Full Text] [Related]

  • 13. Synthesis of spirocyclic sigma1 receptor ligands as potential PET radiotracers, structure-affinity relationships and in vitro metabolic stability.
    Grosse Maestrup E, Wiese C, Schepmann D, Hiller A, Fischer S, Scheunemann M, Brust P, Wünsch B.
    Bioorg Med Chem; 2009 May 15; 17(10):3630-41. PubMed ID: 19394833
    [Abstract] [Full Text] [Related]

  • 14. Evaluation of spirocyclic 3-(3-fluoropropyl)-2-benzofurans as sigma1 receptor ligands for neuroimaging with positron emission tomography.
    Maestrup EG, Fischer S, Wiese C, Schepmann D, Hiller A, Deuther-Conrad W, Steinbach J, Wünsch B, Brust P.
    J Med Chem; 2009 Oct 08; 52(19):6062-72. PubMed ID: 19791807
    [Abstract] [Full Text] [Related]

  • 15. 1-(4-[18F]Fluorobenzyl)-4-[(tetrahydrofuran-2-yl)methyl]piperazine: A Novel Suitable Radioligand with Low Lipophilicity for Imaging σ1 Receptors in the Brain.
    He Y, Xie F, Ye J, Deuther-Conrad W, Cui B, Wang L, Lu J, Steinbach J, Brust P, Huang Y, Lu J, Jia H.
    J Med Chem; 2017 May 25; 60(10):4161-4172. PubMed ID: 28409931
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, radiofluorination and pharmacological evaluation of a fluoromethyl spirocyclic PET tracer for central σ1 receptors and comparison with fluoroalkyl homologs.
    Maisonial A, Grosse Maestrup E, Wiese C, Hiller A, Schepmann D, Fischer S, Deuther-Conrad W, Steinbach J, Brust P, Wünsch B.
    Bioorg Med Chem; 2012 Jan 01; 20(1):257-69. PubMed ID: 22136765
    [Abstract] [Full Text] [Related]

  • 17. A new 18F-labeled fluoroacetylmorpholino derivative of vesamicol for neuroimaging of the vesicular acetylcholine transporter.
    Sorger D, Scheunemann M, Grossmann U, Fischer S, Vercouille J, Hiller A, Wenzel B, Roghani A, Schliebs R, Brust P, Sabri O, Steinbach J.
    Nucl Med Biol; 2008 Feb 01; 35(2):185-95. PubMed ID: 18312828
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and evaluation of [18F]fluoroethyl SA4503 as a PET ligand for the sigma receptor.
    Elsinga PH, Kawamura K, Kobayashi T, Tsukada H, Senda M, Vaalburg W, Ishiwata K.
    Synapse; 2002 Mar 15; 43(4):259-67. PubMed ID: 11835521
    [Abstract] [Full Text] [Related]

  • 19. Fluorinated PET Tracers for Molecular Imaging of σ1 Receptors in the Central Nervous System.
    Weber F, Brust P, Laurini E, Pricl S, Wünsch B.
    Adv Exp Med Biol; 2017 Mar 15; 964():31-48. PubMed ID: 28315263
    [Abstract] [Full Text] [Related]

  • 20. N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands.
    Berardi F, Santoro S, Perrone R, Tortorella V, Govoni S, Lucchi L.
    J Med Chem; 1998 Oct 08; 41(21):3940-7. PubMed ID: 9767631
    [Abstract] [Full Text] [Related]

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