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238 related items for PubMed ID: 25190468

  • 1. Assessment of antidotal efficacy of cholinesterase reactivators against paraoxon: In vitro reactivation kinetics and physicochemical properties.
    Gupta B, Singh N, Sharma R, Foretić B, Musilek K, Kuca K, Acharya J, Satnami ML, Ghosh KK.
    Bioorg Med Chem Lett; 2014 Oct 01; 24(19):4743-4748. PubMed ID: 25190468
    [Abstract] [Full Text] [Related]

  • 2. In vitro reactivation kinetics of paraoxon- and DFP-inhibited electric eel AChE using mono- and bis-pyridinium oximes.
    Gupta B, Sharma R, Singh N, Kuca K, Acharya JR, Ghosh KK.
    Arch Toxicol; 2014 Feb 01; 88(2):381-90. PubMed ID: 24065055
    [Abstract] [Full Text] [Related]

  • 3. Interactions between xylene-linked carbamoyl bis-pyridinium mono-oximes and organophosphates inhibited-AChE: a kinetic study.
    Sharma R, Gupta B, Acharya J, Kaushik MP, Ghosh KK.
    Toxicology; 2014 Feb 28; 316():1-8. PubMed ID: 24345352
    [Abstract] [Full Text] [Related]

  • 4. In silico and in vitro evaluation of two novel oximes (K378 and K727) in comparison to K-27 and pralidoxime against paraoxon-ethyl intoxication.
    Arshad M, Fatmi MQ, Musilek K, Hussain A, Kuca K, Petroianu G, Kalasz H, Nurulain SM.
    Toxicol Mech Methods; 2018 Jan 28; 28(1):62-68. PubMed ID: 28722512
    [Abstract] [Full Text] [Related]

  • 5. Oxime-mediated in vitro reactivation kinetic analysis of organophosphates-inhibited human and electric eel acetylcholinesterase.
    Sahu AK, Sharma R, Gupta B, Musilek K, Kuca K, Acharya J, Ghosh KK.
    Toxicol Mech Methods; 2016 Jun 28; 26(5):319-26. PubMed ID: 27101948
    [Abstract] [Full Text] [Related]

  • 6. Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.
    Musilek K, Holas O, Jun D, Dohnal V, Gunn-Moore F, Opletalova V, Dolezal M, Kuca K.
    Bioorg Med Chem; 2007 Nov 01; 15(21):6733-41. PubMed ID: 17764957
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, Biological Evaluation, and Docking Studies of Novel Bisquaternary Aldoxime Reactivators on Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon.
    Kuca K, Jun D, Junova L, Musilek K, Hrabinova M, da Silva JAV, Ramalho TC, Valko M, Wu Q, Nepovimova E, França TCC.
    Molecules; 2018 May 07; 23(5):. PubMed ID: 29735900
    [Abstract] [Full Text] [Related]

  • 8. In vitro oxime reactivation of red blood cell acetylcholinesterase inhibited by methyl-paraoxon.
    Petroianu GA, Arafat K, Nurulain SM, Kuca K, Kassa J.
    J Appl Toxicol; 2007 May 07; 27(2):168-75. PubMed ID: 17265452
    [Abstract] [Full Text] [Related]

  • 9. Fluorinated pyridinium oximes as potential reactivators for acetylcholinesterases inhibited by paraoxon organophosphorus agent.
    Jeong HC, Park NJ, Chae CH, Musilek K, Kassa J, Kuca K, Jung YS.
    Bioorg Med Chem; 2009 Sep 01; 17(17):6213-7. PubMed ID: 19665386
    [Abstract] [Full Text] [Related]

  • 10. Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
    Musilek K, Holas O, Kuca K, Jun D, Dohnal V, Opletalova V, Dolezal M.
    Bioorg Med Chem Lett; 2007 Jun 01; 17(11):3172-6. PubMed ID: 17383875
    [Abstract] [Full Text] [Related]

  • 11. Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase.
    Winter M, Wille T, Musilek K, Kuca K, Thiermann H, Worek F.
    Toxicol Lett; 2016 Feb 26; 244():136-142. PubMed ID: 26210933
    [Abstract] [Full Text] [Related]

  • 12. Kinetic studies and structure-activity relationships of bispyridinium oximes as reactivators of acetylcholinesterase inhibited by organophosphorus compounds.
    Su CT, Wang PH, Liu RF, Shih JH, Ma C, Lin CH, Liu CY, Wu MT.
    Fundam Appl Toxicol; 1986 Apr 26; 6(3):506-14. PubMed ID: 3699334
    [Abstract] [Full Text] [Related]

  • 13. In vitro reactivation of sarin-inhibited human acetylcholinesterase (AChE) by bis-pyridinium oximes connected by xylene linkers.
    Acharya J, Dubey DK, Srivastava AK, Raza SK.
    Toxicol In Vitro; 2011 Feb 26; 25(1):251-6. PubMed ID: 20688148
    [Abstract] [Full Text] [Related]

  • 14. Rational design, synthesis, and evaluation of uncharged, "smart" bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase.
    Gorecki L, Gerlits O, Kong X, Cheng X, Blumenthal DK, Taylor P, Ballatore C, Kovalevsky A, Radić Z.
    J Biol Chem; 2020 Mar 27; 295(13):4079-4092. PubMed ID: 32019865
    [Abstract] [Full Text] [Related]

  • 15. Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes.
    Oh KA, Park NJ, Park NS, Kuca K, Jun D, Jung YS.
    Chem Biol Interact; 2008 Sep 25; 175(1-3):365-7. PubMed ID: 18565503
    [Abstract] [Full Text] [Related]

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  • 17. Reactivation kinetics of a homologous series of bispyridinium bis-oximes with nerve agent-inhibited human acetylcholinesterase.
    Worek F, von der Wellen J, Musilek K, Kuca K, Thiermann H.
    Arch Toxicol; 2012 Sep 25; 86(9):1379-86. PubMed ID: 22437842
    [Abstract] [Full Text] [Related]

  • 18. Comparison of the reactivation rates of acetylcholinesterase modified by structurally different organophosphates using novel pyridinium oximes.
    Bharate SB, Chao CK, Thompson CM.
    Environ Toxicol Pharmacol; 2019 Oct 25; 71():103218. PubMed ID: 31302432
    [Abstract] [Full Text] [Related]

  • 19. Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: in vitro reactivation of red blood cell acetylcholinesterase inhibited by paraoxon.
    Petroianu GA, Arafat K, Kuca K, Kassa J.
    J Appl Toxicol; 2006 Oct 25; 26(1):64-71. PubMed ID: 16193529
    [Abstract] [Full Text] [Related]

  • 20. Reactivation kinetics of 31 structurally different bispyridinium oximes with organophosphate-inhibited human butyrylcholinesterase.
    Horn G, Wille T, Musilek K, Kuca K, Thiermann H, Worek F.
    Arch Toxicol; 2015 Mar 25; 89(3):405-14. PubMed ID: 24912784
    [Abstract] [Full Text] [Related]

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