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Journal Abstract Search
260 related items for PubMed ID: 25199627
1. Hypoxia diminishes the detoxification of the environmental mutagen benzo[a]pyrene. Schults MA, Sanen K, Godschalk RW, Theys J, van Schooten FJ, Chiu RK. Mutagenesis; 2014 Nov; 29(6):481-7. PubMed ID: 25199627 [Abstract] [Full Text] [Related]
2. Protective efficacy of hGSTM1-1 against B[a]P and (+)- or (-)-B[a]P-7,8-dihydrodiol cytotoxicity, mutagenicity, and macromolecular adducts in V79 cells coexpressing hCYP1A1. Kushman ME, Kabler SL, Ahmad S, Doehmer J, Morrow CS, Townsend AJ. Toxicol Sci; 2007 Sep; 99(1):51-7. PubMed ID: 17525473 [Abstract] [Full Text] [Related]
3. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1. Kushman ME, Kabler SL, Fleming MH, Ravoori S, Gupta RC, Doehmer J, Morrow CS, Townsend AJ. Carcinogenesis; 2007 Jan; 28(1):207-14. PubMed ID: 16885195 [Abstract] [Full Text] [Related]
4. Genetic polymorphisms in biotransformation enzymes for benzo[a]pyrene and related levels of benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA adducts in Goeckerman therapy. Beranek M, Fiala Z, Kremlacek J, Andrys C, Hamakova K, Chmelarova M, Palicka V, Borska L. Toxicol Lett; 2016 Jul 25; 255():47-51. PubMed ID: 27188524 [Abstract] [Full Text] [Related]
5. Inhibitory effects of chrysoeriol on DNA adduct formation with benzo[a]pyrene in MCF-7 breast cancer cells. Takemura H, Nagayoshi H, Matsuda T, Sakakibara H, Morita M, Matsui A, Ohura T, Shimoi K. Toxicology; 2010 Jul 25; 274(1-3):42-8. PubMed ID: 20553787 [Abstract] [Full Text] [Related]
7. The relationship between DNA adduct formation by benzo[a]pyrene and expression of its activation enzyme cytochrome P450 1A1 in rat. Hodek P, Koblihová J, Kizek R, Frei E, Arlt VM, Stiborová M. Environ Toxicol Pharmacol; 2013 Nov 25; 36(3):989-96. PubMed ID: 24095716 [Abstract] [Full Text] [Related]
10. Contrasting disposition and metabolism of topically applied benzo(a)pyrene, trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and 7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in mouse epidermis in vivo. Melikian AA, Bagheri K, Hecht SS. Cancer Res; 1987 Oct 15; 47(20):5354-60. PubMed ID: 3115566 [Abstract] [Full Text] [Related]
11. Differences in the DNA adducts formed in cultured rabbit and rat dermal fibroblasts by benzo(a)pyrene and (-)benzo(a)pyrene-7,8-diol. Alexandrov K, Sala M, Rojas M. Cancer Res; 1988 Dec 15; 48(24 Pt 1):7132-9. PubMed ID: 3142683 [Abstract] [Full Text] [Related]
12. Detoxification: a novel function of BRCA1 in tumor suppression? Kang HJ, Hong YB, Kim HJ, Rodriguez OC, Nath RG, Tilli EM, Albanese C, Chung FL, Kwon SH, Bae I. Toxicol Sci; 2011 Jul 15; 122(1):26-37. PubMed ID: 21507987 [Abstract] [Full Text] [Related]
14. Dioxin suppresses benzo[a]pyrene-induced mutations and DNA adduct formation through cytochrome P450 1A1 induction and (±)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide inactivation in human hepatoma cells. Shiizaki K, Kawanishi M, Yagi T. Mutat Res; 2013 Jan 20; 750(1-2):77-85. PubMed ID: 23036853 [Abstract] [Full Text] [Related]
17. Diminished carcinogen detoxification is a novel mechanism for hypoxia-inducible factor 1-mediated genetic instability. Schults MA, Timmermans L, Godschalk RW, Theys J, Wouters BG, van Schooten FJ, Chiu RK. J Biol Chem; 2010 May 07; 285(19):14558-64. PubMed ID: 20228066 [Abstract] [Full Text] [Related]
18. Chinese medicinal herbs modulate mutagenesis, DNA binding and metabolism of benzo[a]pyrene 7,8-dihydrodiol and benzo[a]pyrene 7,8-dihydrodiol-9,10-epoxide. Wong BY, Lau BH, Teel RW. Cancer Lett; 1992 Feb 29; 62(2):123-31. PubMed ID: 1540939 [Abstract] [Full Text] [Related]