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Journal Abstract Search


225 related items for PubMed ID: 25210872

  • 1. Development of inhibitors of the 2C-methyl-D-erythritol 4-phosphate (MEP) pathway enzymes as potential anti-infective agents.
    Masini T, Hirsch AK.
    J Med Chem; 2014 Dec 11; 57(23):9740-63. PubMed ID: 25210872
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  • 2. Methylerythritol phosphate pathway to isoprenoids: kinetic modeling and in silico enzyme inhibitions in Plasmodium falciparum.
    Singh VK, Ghosh I.
    FEBS Lett; 2013 Sep 02; 587(17):2806-17. PubMed ID: 23816706
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  • 3. Nonmevalonate terpene biosynthesis enzymes as antiinfective drug targets: substrate synthesis and high-throughput screening methods.
    Illarionova V, Kaiser J, Ostrozhenkova E, Bacher A, Fischer M, Eisenreich W, Rohdich F.
    J Org Chem; 2006 Nov 10; 71(23):8824-34. PubMed ID: 17081012
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  • 4. Targeting the methyl erythritol phosphate (MEP) pathway for novel antimalarial, antibacterial and herbicidal drug discovery: inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme.
    Singh N, Chevé G, Avery MA, McCurdy CR.
    Curr Pharm Des; 2007 Nov 10; 13(11):1161-77. PubMed ID: 17430177
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  • 7. The methylerythritol phosphate (MEP) pathway for isoprenoid biosynthesis as a target for the development of new drugs against tuberculosis.
    Obiol-Pardo C, Rubio-Martinez J, Imperial S.
    Curr Med Chem; 2011 Nov 10; 18(9):1325-38. PubMed ID: 21366531
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  • 10. Isoprenoid biosynthesis via the methylerythritol phosphate pathway: structural variations around phosphonate anchor and spacer of fosmidomycin, a potent inhibitor of deoxyxylulose phosphate reductoisomerase.
    Zinglé C, Kuntz L, Tritsch D, Grosdemange-Billiard C, Rohmer M.
    J Org Chem; 2010 May 21; 75(10):3203-7. PubMed ID: 20429517
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  • 13. Co-expression of three MEP pathway genes and geraniol 10-hydroxylase in internal phloem parenchyma of Catharanthus roseus implicates multicellular translocation of intermediates during the biosynthesis of monoterpene indole alkaloids and isoprenoid-derived primary metabolites.
    Burlat V, Oudin A, Courtois M, Rideau M, St-Pierre B.
    Plant J; 2004 Apr 21; 38(1):131-41. PubMed ID: 15053766
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  • 14. The methylerythritol phosphate pathway and its significance as a novel drug target.
    Testa CA, Brown MJ.
    Curr Pharm Biotechnol; 2003 Aug 21; 4(4):248-59. PubMed ID: 14529427
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  • 15. The MEP pathway: a new target for the development of herbicides, antibiotics and antimalarial drugs.
    Rodríguez-Concepción M.
    Curr Pharm Des; 2004 Aug 21; 10(19):2391-400. PubMed ID: 15279616
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  • 20. Structural studies on Mycobacterium tuberculosis DXR in complex with the antibiotic FR-900098.
    Björkelid C, Bergfors T, Unge T, Mowbray SL, Jones TA.
    Acta Crystallogr D Biol Crystallogr; 2012 Feb 21; 68(Pt 2):134-43. PubMed ID: 22281742
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