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Journal Abstract Search

288 related items for PubMed ID: 25213861

  • 1. Nuclear enrichment of folate cofactors and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) protect de novo thymidylate biosynthesis during folate deficiency.
    Field MS, Kamynina E, Agunloye OC, Liebenthal RP, Lamarre SG, Brosnan ME, Brosnan JT, Stover PJ.
    J Biol Chem; 2014 Oct 24; 289(43):29642-50. PubMed ID: 25213861
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  • 3. Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism.
    MacFarlane AJ, Perry CA, Girnary HH, Gao D, Allen RH, Stabler SP, Shane B, Stover PJ.
    J Biol Chem; 2009 Jan 16; 284(3):1533-9. PubMed ID: 19033438
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  • 5. Human mutations in methylenetetrahydrofolate dehydrogenase 1 impair nuclear de novo thymidylate biosynthesis.
    Field MS, Kamynina E, Watkins D, Rosenblatt DS, Stover PJ.
    Proc Natl Acad Sci U S A; 2015 Jan 13; 112(2):400-5. PubMed ID: 25548164
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  • 7. Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNA.
    MacFarlane AJ, Anderson DD, Flodby P, Perry CA, Allen RH, Stabler SP, Stover PJ.
    J Biol Chem; 2011 Dec 23; 286(51):44015-44022. PubMed ID: 22057276
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  • 11. Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration.
    Field MS, Shields KS, Abarinov EV, Malysheva OV, Allen RH, Stabler SP, Ash JA, Strupp BJ, Stover PJ, Caudill MA.
    J Nutr; 2013 Jan 23; 143(1):41-5. PubMed ID: 23190757
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  • 17. Altered folate metabolism modifies cell proliferation and progesterone secretion in human placental choriocarcinoma JEG-3 cells.
    Moussa C, Ross N, Jolette P, MacFarlane AJ.
    Br J Nutr; 2015 Sep 28; 114(6):844-52. PubMed ID: 26299783
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  • 18. Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells.
    Green AC, Marttila P, Kiweler N, Chalkiadaki C, Wiita E, Cookson V, Lesur A, Eiden K, Bernardin F, Vallin KSA, Borhade S, Long M, Ghahe EK, Jiménez-Alonso JJ, Jemth AS, Loseva O, Mortusewicz O, Meyers M, Viry E, Johansson AI, Hodek O, Homan E, Bonagas N, Ramos L, Sandberg L, Frödin M, Moussay E, Slipicevic A, Letellier E, Paggetti J, Sørensen CS, Helleday T, Henriksson M, Meiser J.
    Nat Metab; 2023 Apr 28; 5(4):642-659. PubMed ID: 37012496
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  • 19. Cell cycle regulation of folate-mediated one-carbon metabolism.
    Lan X, Field MS, Stover PJ.
    Wiley Interdiscip Rev Syst Biol Med; 2018 Nov 28; 10(6):e1426. PubMed ID: 29889360
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