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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

360 related items for PubMed ID: 25216392

  • 1. Design, synthesis, biological screening, and molecular docking studies of piperazine-derived constrained inhibitors of DPP-IV for the treatment of type 2 diabetes.
    Kushwaha RN, Srivastava R, Mishra A, Rawat AK, Srivastava AK, Haq W, Katti SB.
    Chem Biol Drug Des; 2015 Apr; 85(4):439-46. PubMed ID: 25216392
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological evaluation of pyrrolidine-2-carbonitrile and 4-fluoropyrrolidine-2-carbonitrile derivatives as dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes.
    Wang J, Feng Y, Ji X, Deng G, Leng Y, Liu H.
    Bioorg Med Chem; 2013 Dec 01; 21(23):7418-29. PubMed ID: 24153396
    [Abstract] [Full Text] [Related]

  • 3. Synthesis, evaluation and molecular docking of prolyl-fluoropyrrolidine derivatives as dipeptidyl peptidase IV inhibitors.
    Sharma M, Gupta M, Singh D, Kumar M, Kaur P.
    Chem Biol Drug Des; 2013 Aug 01; 82(2):156-66. PubMed ID: 23581745
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, evaluation and molecular docking of thiazolopyrimidine derivatives as dipeptidyl peptidase IV inhibitors.
    Sharma M, Gupta M, Singh D, Kumar M, Kaur P.
    Chem Biol Drug Des; 2012 Dec 01; 80(6):918-28. PubMed ID: 22943413
    [Abstract] [Full Text] [Related]

  • 5. Identification of dipeptidyl peptidase IV inhibitors: virtual screening, synthesis and biological evaluation.
    Xing J, Li Q, Zhang S, Liu H, Zhao L, Cheng H, Zhang Y, Zhou J, Zhang H.
    Chem Biol Drug Des; 2014 Sep 01; 84(3):364-77. PubMed ID: 24674599
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and evaluation of camphor and cytisine-based cyanopyrrolidines as DPP-IV inhibitors for the treatment of type 2 diabetes mellitus.
    Kuranov SO, Tsypysheva IP, Khvostov MV, Zainullina LF, Borisevich SS, Vakhitova YV, Luzina OA, Salakhutdinov NF.
    Bioorg Med Chem; 2018 Aug 15; 26(15):4402-4409. PubMed ID: 30056037
    [Abstract] [Full Text] [Related]

  • 7. Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): a highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
    Yoshida T, Akahoshi F, Sakashita H, Kitajima H, Nakamura M, Sonda S, Takeuchi M, Tanaka Y, Ueda N, Sekiguchi S, Ishige T, Shima K, Nabeno M, Abe Y, Anabuki J, Soejima A, Yoshida K, Takashina Y, Ishii S, Kiuchi S, Fukuda S, Tsutsumiuchi R, Kosaka K, Murozono T, Nakamaru Y, Utsumi H, Masutomi N, Kishida H, Miyaguchi I, Hayashi Y.
    Bioorg Med Chem; 2012 Oct 01; 20(19):5705-19. PubMed ID: 22959556
    [Abstract] [Full Text] [Related]

  • 8. Novel 4-heteroaryl-antipyrines as DPP-IV inhibitors.
    Gomha SM, Eldebss TM, Badrey MG, Abdulla MM, Mayhoub AS.
    Chem Biol Drug Des; 2015 Nov 01; 86(5):1292-303. PubMed ID: 26032047
    [Abstract] [Full Text] [Related]

  • 9. Synthesis, Biological Evaluation, and Molecular Docking of (R)-2-((8-(3-aminopiperidin-1-yl)-3-methyl-7-(3-methylbut-2-en-1-yl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl)benzonitrile as Dipeptidyl Peptidase IV Inhibitors.
    Ran Y, Pei H, Shao M, Chen L.
    Chem Biol Drug Des; 2016 Feb 01; 87(2):290-5. PubMed ID: 26426933
    [Abstract] [Full Text] [Related]

  • 10. Discovery of potent, selective, and orally bioavailable quinoline-based dipeptidyl peptidase IV inhibitors targeting Lys554.
    Maezaki H, Banno Y, Miyamoto Y, Moritoh Y, Asakawa T, Kataoka O, Takeuchi K, Suzuki N, Ikedo K, Kosaka T, Sasaki M, Tsubotani S, Tani A, Funami M, Yamamoto Y, Tawada M, Aertgeerts K, Yano J, Oi S.
    Bioorg Med Chem; 2011 Aug 01; 19(15):4482-98. PubMed ID: 21741847
    [Abstract] [Full Text] [Related]

  • 11. [Design, synthesis and characterization of cyanopyrrolidine-bearing compounds as DPP-4 inhibitors].
    Wang W, Jiang H, Pang J, Jiang Z, Xi B.
    Nan Fang Yi Ke Da Xue Xue Bao; 2012 Feb 01; 32(2):177-80. PubMed ID: 22381752
    [Abstract] [Full Text] [Related]

  • 12. Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.
    Li N, Wang LJ, Jiang B, Li XQ, Guo CL, Guo SJ, Shi DY.
    Eur J Med Chem; 2018 May 10; 151():145-157. PubMed ID: 29609120
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis, biological evaluation, and docking studies of (s)-phenylalanine derivatives with a 2-cyanopyrrolidine moiety as potent dipeptidyl peptidase 4 inhibitors.
    Liu Y, Wu Y, Wu H, Tang L, Wu P, Liu T, Hu Y.
    Chem Biol Drug Des; 2013 Aug 10; 82(2):140-6. PubMed ID: 23530834
    [Abstract] [Full Text] [Related]

  • 14. RBx-0597, a potent, selective and slow-binding inhibitor of dipeptidyl peptidase-IV for the treatment of type 2 diabetes.
    Singh S, Roy S, Sethi S, Benjamin B, Sundaram S, Khanna V, Kandalkar SR, Pal C, Kant R, Patra AK, Rayasam G, Mittra S, Saini KS, Paliwal J, Chugh A, Ahmed S, Sattigeri J, Cliff I, Ray A, Bansal VS, Bhatnagar PK, Davis JA.
    Eur J Pharmacol; 2011 Feb 10; 652(1-3):157-63. PubMed ID: 20540938
    [Abstract] [Full Text] [Related]

  • 15. Dipeptidyl peptidase-4 inhibitor with β-amino amide scaffold: synthesis, SAR and biological evaluation.
    Kim HJ, Kwak WY, Min JP, Sung SY, Kim HD, Kim MK, Kim HS, Park KJ, Son MH, Kim SH, Lee BJ.
    Bioorg Med Chem Lett; 2012 Sep 01; 22(17):5545-9. PubMed ID: 22850208
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and biological evaluation of triazole based uracil derivatives as novel DPP-4 inhibitors.
    Li Q, Han L, Zhang B, Zhou J, Zhang H.
    Org Biomol Chem; 2016 Oct 12; 14(40):9598-9611. PubMed ID: 27714283
    [Abstract] [Full Text] [Related]

  • 17. Finding a Potential Dipeptidyl Peptidase-4 (DPP-4) Inhibitor for Type-2 Diabetes Treatment Based on Molecular Docking, Pharmacophore Generation, and Molecular Dynamics Simulation.
    Meduru H, Wang YT, Tsai JJ, Chen YC.
    Int J Mol Sci; 2016 Jun 13; 17(6):. PubMed ID: 27304951
    [Abstract] [Full Text] [Related]

  • 18. Discovery of 3H-imidazo[4,5-c]quinolin-4(5H)-ones as potent and selective dipeptidyl peptidase IV (DPP-4) inhibitors: use of a carboxylate prodrug to improve bioavailability.
    Ikuma Y, Hochigai H, Kimura H, Nunami N, Kobayashi T, Uchiyama K, Umezome T, Sakurai Y, Sawada N, Tadano J, Sugaru E, Ono M, Hirose Y, Nakahira H.
    Bioorg Med Chem; 2015 Feb 15; 23(4):779-90. PubMed ID: 25596166
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis and anti-diabetic activity of triazolotriazine derivatives as dipeptidyl peptidase-4 (DPP-4) inhibitors.
    Patel BD, Bhadada SV, Ghate MD.
    Bioorg Chem; 2017 Jun 15; 72():345-358. PubMed ID: 28302310
    [Abstract] [Full Text] [Related]

  • 20. Design, Synthesis and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel DPP-4 Inhibitors.
    Li Q, Zhou M, Han L, Cao Q, Wang X, Zhao L, Zhou J, Zhang H.
    Chem Biol Drug Des; 2015 Oct 15; 86(4):849-56. PubMed ID: 25787859
    [Abstract] [Full Text] [Related]

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