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Journal Abstract Search

357 related items for PubMed ID: 25217461

  • 21. A chemical rescue screen identifies a Plasmodium falciparum apicoplast inhibitor targeting MEP isoprenoid precursor biosynthesis.
    Wu W, Herrera Z, Ebert D, Baska K, Cho SH, DeRisi JL, Yeh E.
    Antimicrob Agents Chemother; 2015 Jan; 59(1):356-64. PubMed ID: 25367906
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  • 22. In vitro and in vivo synergy of fosmidomycin, a novel antimalarial drug, with clindamycin.
    Wiesner J, Henschker D, Hutchinson DB, Beck E, Jomaa H.
    Antimicrob Agents Chemother; 2002 Sep; 46(9):2889-94. PubMed ID: 12183243
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  • 23. MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis.
    Edwards RL, Brothers RC, Wang X, Maron MI, Ziniel PD, Tsang PS, Kraft TE, Hruz PW, Williamson KC, Dowd CS, John ARO.
    Sci Rep; 2017 Aug 21; 7(1):8400. PubMed ID: 28827774
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  • 27. Apicoplast-derived isoprenoids are essential for biosynthesis of GPI protein anchors, and consequently for egress and invasion in Plasmodium falciparum.
    Bulloch MS, Huynh LK, Kennedy K, Ralton JE, McConville MJ, Ralph SA.
    PLoS Pathog; 2024 Sep 21; 20(9):e1012484. PubMed ID: 39241090
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  • 28. Apicoplast Metabolism: Parasite's Achilles' Heel.
    Kadian K, Gupta Y, Singh HV, Kempaiah P, Rawat M.
    Curr Top Med Chem; 2018 Sep 21; 18(22):1987-1997. PubMed ID: 30499407
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  • 29. Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking.
    Kennedy K, Cobbold SA, Hanssen E, Birnbaum J, Spillman NJ, McHugh E, Brown H, Tilley L, Spielmann T, McConville MJ, Ralph SA.
    PLoS Biol; 2019 Jul 21; 17(7):e3000376. PubMed ID: 31318858
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  • 30. Fosmidomycin-clindamycin for the treatment of Plasmodium falciparum malaria.
    Borrmann S, Issifou S, Esser G, Adegnika AA, Ramharter M, Matsiegui PB, Oyakhirome S, Mawili-Mboumba DP, Missinou MA, Kun JF, Jomaa H, Kremsner PG.
    J Infect Dis; 2004 Nov 01; 190(9):1534-40. PubMed ID: 15478056
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  • 31. Critical role for isoprenoids in apicoplast biogenesis by malaria parasites.
    Okada M, Rajaram K, Swift RP, Mixon A, Maschek JA, Prigge ST, Sigala PA.
    Elife; 2022 Mar 08; 11():. PubMed ID: 35257658
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  • 32. Methylerythritol phosphate pathway to isoprenoids: kinetic modeling and in silico enzyme inhibitions in Plasmodium falciparum.
    Singh VK, Ghosh I.
    FEBS Lett; 2013 Sep 02; 587(17):2806-17. PubMed ID: 23816706
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  • 33. Prodrugs of reverse fosmidomycin analogues.
    Brücher K, Gräwert T, Konzuch S, Held J, Lienau C, Behrendt C, Illarionov B, Maes L, Bacher A, Wittlin S, Mordmüller B, Fischer M, Kurz T.
    J Med Chem; 2015 Feb 26; 58(4):2025-35. PubMed ID: 25633870
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  • 34. Fosmidomycin as an antimalarial drug: a meta-analysis of clinical trials.
    Fernandes JF, Lell B, Agnandji ST, Obiang RM, Bassat Q, Kremsner PG, Mordmüller B, Grobusch MP.
    Future Microbiol; 2015 Feb 26; 10(8):1375-90. PubMed ID: 26228767
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  • 37. Whole-Genome Sequencing to Evaluate the Resistance Landscape Following Antimalarial Treatment Failure With Fosmidomycin-Clindamycin.
    Guggisberg AM, Sundararaman SA, Lanaspa M, Moraleda C, González R, Mayor A, Cisteró P, Hutchinson D, Kremsner PG, Hahn BH, Bassat Q, Odom AR.
    J Infect Dis; 2016 Oct 01; 214(7):1085-91. PubMed ID: 27443612
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  • 38. Distinct light-mediated pathways regulate the biosynthesis and exchange of isoprenoid precursors during Arabidopsis seedling development.
    Rodríguez-Concepción M, Forés O, Martinez-García JF, González V, Phillips MA, Ferrer A, Boronat A.
    Plant Cell; 2004 Jan 01; 16(1):144-56. PubMed ID: 14660801
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  • 39. Amino acid based prodrugs of a fosmidomycin surrogate as antimalarial and antitubercular agents.
    Courtens C, Risseeuw M, Caljon G, Maes L, Martin A, Van Calenbergh S.
    Bioorg Med Chem; 2019 Mar 01; 27(5):729-747. PubMed ID: 30692024
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