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166 related items for PubMed ID: 25230982

  • 1. Monoclonal antibody G250 targeting CA Ⅸ: Binding specificity, internalization and therapeutic effects in a non-renal cancer model.
    Zatovicova M, Jelenska L, Hulikova A, Ditte P, Ditte Z, Csaderova L, Svastova E, Schmalix W, Boettger V, Bevan P, Pastorek J, Pastorekova S.
    Int J Oncol; 2014 Dec; 45(6):2455-67. PubMed ID: 25230982
    [Abstract] [Full Text] [Related]

  • 2. Carbonic anhydrase IX as an anticancer therapy target: preclinical evaluation of internalizing monoclonal antibody directed to catalytic domain.
    Zatovicova M, Jelenska L, Hulikova A, Csaderova L, Ditte Z, Ditte P, Goliasova T, Pastorek J, Pastorekova S.
    Curr Pharm Des; 2010 Dec; 16(29):3255-63. PubMed ID: 20819068
    [Abstract] [Full Text] [Related]

  • 3. Biodistribution and pharmacokinetics of 125I-labeled monoclonal antibody M75 specific for carbonic anhydrase IX, an intrinsic marker of hypoxia, in nude mice xenografted with human colorectal carcinoma.
    Chrastina A, Závada J, Parkkila S, Kaluz S, Kaluzová M, Rajcáni J, Pastorek J, Pastoreková S.
    Int J Cancer; 2003 Jul 20; 105(6):873-81. PubMed ID: 12767076
    [Abstract] [Full Text] [Related]

  • 4. G250: a carbonic anhydrase IX monoclonal antibody.
    Lam JS, Pantuck AJ, Belldegrun AS, Figlin RA.
    Curr Oncol Rep; 2005 Mar 20; 7(2):109-15. PubMed ID: 15717944
    [Abstract] [Full Text] [Related]

  • 5. Interferons can upregulate the expression of the tumor associated antigen G250-MN/CA IX, a potential target for (radio)immunotherapy of renal cell carcinoma.
    Brouwers AH, Frielink C, Oosterwijk E, Oyen WJ, Corstens FH, Boerman OC.
    Cancer Biother Radiopharm; 2003 Aug 20; 18(4):539-47. PubMed ID: 14503948
    [Abstract] [Full Text] [Related]

  • 6. Human anti-CAIX antibodies mediate immune cell inhibition of renal cell carcinoma in vitro and in a humanized mouse model in vivo.
    Chang DK, Moniz RJ, Xu Z, Sun J, Signoretti S, Zhu Q, Marasco WA.
    Mol Cancer; 2015 Jun 11; 14():119. PubMed ID: 26062742
    [Abstract] [Full Text] [Related]

  • 7. Investigation of hypoxia and carbonic anhydrase IX expression in a renal cell carcinoma xenograft model with oxygen tension measurements and ¹²⁴I-cG250 PET/CT.
    Lawrentschuk N, Lee FT, Jones G, Rigopoulos A, Mountain A, O'Keefe G, Papenfuss AT, Bolton DM, Davis ID, Scott AM.
    Urol Oncol; 2011 Jun 11; 29(4):411-20. PubMed ID: 19523858
    [Abstract] [Full Text] [Related]

  • 8. Specific monoclonal antibody-based immunotherapy by targeting the RCC-associated antigen carbonic anhydrase-IX(G250/MN).
    Mulders P, Bleumer I, Debruyne F, Oosterwijk E.
    Urologe A; 2004 Sep 11; 43 Suppl 3():S146-7. PubMed ID: 15164181
    [No Abstract] [Full Text] [Related]

  • 9. The novel CA IX inhibition antibody chKM4927 shows anti-tumor efficacy in vivo.
    Yamaguchi A, Usami K, Shimabe M, Hasegawa K, Asada M, Motoki K, Tahara T, Masuda K.
    Anticancer Res; 2015 Apr 11; 35(4):1997-2004. PubMed ID: 25862852
    [Abstract] [Full Text] [Related]

  • 10. MN/CA IX/G250 as a potential target for immunotherapy of renal cell carcinomas.
    Uemura H, Nakagawa Y, Yoshida K, Saga S, Yoshikawa K, Hirao Y, Oosterwijk E.
    Br J Cancer; 1999 Oct 11; 81(4):741-6. PubMed ID: 10574265
    [Abstract] [Full Text] [Related]

  • 11. Monoclonal antibodies generated in carbonic anhydrase IX-deficient mice recognize different domains of tumour-associated hypoxia-induced carbonic anhydrase IX.
    Zat'ovicová M, Tarábková K, Svastová E, Gibadulinová A, Mucha V, Jakubícková L, Biesová Z, Rafajová M, Ortova Gut M, Parkkila S, Parkkila AK, Waheed A, Sly WS, Horak I, Pastorek J, Pastoreková S.
    J Immunol Methods; 2003 Nov 11; 282(1-2):117-34. PubMed ID: 14604546
    [Abstract] [Full Text] [Related]

  • 12. Unique biological properties of catalytic domain directed human anti-CAIX antibodies discovered through phage-display technology.
    Xu C, Lo A, Yammanuru A, Tallarico AS, Brady K, Murakami A, Barteneva N, Zhu Q, Marasco WA.
    PLoS One; 2010 Mar 10; 5(3):e9625. PubMed ID: 20224781
    [Abstract] [Full Text] [Related]

  • 13. Anti-renal-cell carcinoma chimeric antibody G250 facilitates antibody-dependent cellular cytotoxicity with in vitro and in vivo interleukin-2-activated effectors.
    Surfus JE, Hank JA, Oosterwijk E, Welt S, Lindstrom MJ, Albertini MR, Schiller JH, Sondel PM.
    J Immunother Emphasis Tumor Immunol; 1996 May 10; 19(3):184-91. PubMed ID: 8811493
    [Abstract] [Full Text] [Related]

  • 14. Hypoxia-inducible expression of the mouse carbonic anhydrase IX demonstrated by new monoclonal antibodies.
    Takacova M, Barathova M, Hulikova A, Ohradanova A, Kopacek J, Parkkila S, Pastorek J, Pastorekova S, Zatovicova M.
    Int J Oncol; 2007 Nov 10; 31(5):1103-10. PubMed ID: 17912436
    [Abstract] [Full Text] [Related]

  • 15. Antibody-mediated endocytosis of G250 tumor-associated antigen allows targeted gene transfer to human renal cell carcinoma in vitro.
    Dürrbach A, Angevin E, Poncet P, Rouleau M, Chavanel G, Chapel A, Thierry D, Gorter A, Hirsch R, Charpentier B, Senik A, Hirsch F.
    Cancer Gene Ther; 1999 Nov 10; 6(6):564-71. PubMed ID: 10608353
    [Abstract] [Full Text] [Related]

  • 16. Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: from biology to clinical use.
    Pastorek J, Pastorekova S.
    Semin Cancer Biol; 2015 Apr 10; 31():52-64. PubMed ID: 25117006
    [Abstract] [Full Text] [Related]

  • 17. Imaging of CAIX-expressing xenografts in vivo using 99mTc-HEHEHE-ZCAIX:1 affibody molecule.
    Honarvar H, Garousi J, Gunneriusson E, Höidén-Guthenberg I, Altai M, Widström C, Tolmachev V, Frejd FY.
    Int J Oncol; 2015 Feb 10; 46(2):513-20. PubMed ID: 25434612
    [Abstract] [Full Text] [Related]

  • 18. Generation of chimeric bispecific G250/anti-CD3 monoclonal antibody, a tool to combat renal cell carcinoma.
    Luiten RM, Coney LR, Fleuren GJ, Warnaar SO, Litvinov SV.
    Br J Cancer; 1996 Sep 10; 74(5):735-44. PubMed ID: 8795576
    [Abstract] [Full Text] [Related]

  • 19. Carbonic anhydrase IX expression in prostate cancer.
    Smyth LG, O'Hurley G, O'Grady A, Fitzpatrick JM, Kay E, Watson RW.
    Prostate Cancer Prostatic Dis; 2010 Jun 10; 13(2):178-81. PubMed ID: 20038959
    [Abstract] [Full Text] [Related]

  • 20. A tumor targeted gene vector modified with G250 monoclonal antibody for gene therapy.
    Duan Y, Zheng J, Han S, Wu Y, Wang Y, Li D, Kong D, Yu Y.
    J Control Release; 2008 Apr 21; 127(2):173-9. PubMed ID: 18316136
    [Abstract] [Full Text] [Related]

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