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326 related items for PubMed ID: 25240837

  • 1. Curcumin induces apoptosis of multidrug-resistant human leukemia HL60 cells by complex pathways leading to ceramide accumulation.
    Shakor AB, Atia M, Ismail IA, Alshehri A, El-Refaey H, Kwiatkowska K, Sobota A.
    Biochim Biophys Acta; 2014 Dec; 1841(12):1672-82. PubMed ID: 25240837
    [Abstract] [Full Text] [Related]

  • 2. Ceramide generation during curcumin-induced apoptosis is controlled by crosstalk among Bcl-2, Bcl-xL, caspases and glutathione.
    Abdel Shakor AB, Atia M, Alshehri AS, Sobota A, Kwiatkowska K.
    Cell Signal; 2015 Nov; 27(11):2220-30. PubMed ID: 26232616
    [Abstract] [Full Text] [Related]

  • 3. Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR.
    Tang XQ, Bi H, Feng JQ, Cao JG.
    Acta Pharmacol Sin; 2005 Aug; 26(8):1009-16. PubMed ID: 16038636
    [Abstract] [Full Text] [Related]

  • 4. Possible role of ceramide as an indicator of chemoresistance: decrease of the ceramide content via activation of glucosylceramide synthase and sphingomyelin synthase in chemoresistant leukemia.
    Itoh M, Kitano T, Watanabe M, Kondo T, Yabu T, Taguchi Y, Iwai K, Tashima M, Uchiyama T, Okazaki T.
    Clin Cancer Res; 2003 Jan; 9(1):415-23. PubMed ID: 12538495
    [Abstract] [Full Text] [Related]

  • 5. Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide.
    Lovat PE, Di Sano F, Corazzari M, Fazi B, Donnorso RP, Pearson AD, Hall AG, Redfern CP, Piacentini M.
    J Natl Cancer Inst; 2004 Sep 01; 96(17):1288-99. PubMed ID: 15339967
    [Abstract] [Full Text] [Related]

  • 6. P-glycoprotein is implicated in the inhibition of ceramide-induced apoptosis in TF-1 acute myeloid leukemia cells by modulation of the glucosylceramide synthase pathway.
    Turzanski J, Grundy M, Shang S, Russell N, Pallis M.
    Exp Hematol; 2005 Jan 01; 33(1):62-72. PubMed ID: 15661399
    [Abstract] [Full Text] [Related]

  • 7. Alteration of the daunorubicin-triggered sphingomyelin-ceramide pathway and apoptosis in MDR cells: influence of drug transport abnormalities.
    Côme MG, Bettaieb A, Skladanowski A, Larsen AK, Laurent G.
    Int J Cancer; 1999 May 17; 81(4):580-7. PubMed ID: 10225448
    [Abstract] [Full Text] [Related]

  • 8. beta(2)-microglobulin induces apoptosis in HL-60 human leukemia cell line and its multidrug resistant variants overexpressing MRP1 but lacking Bax or overexpressing P-glycoprotein.
    Wu CH, Rastegar M, Gordon J, Safa AR.
    Oncogene; 2001 Oct 25; 20(48):7006-20. PubMed ID: 11704825
    [Abstract] [Full Text] [Related]

  • 9. Stichoposide C induces apoptosis through the generation of ceramide in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
    Yun SH, Park ES, Shin SW, Na YW, Han JY, Jeong JS, Shastina VV, Stonik VA, Park JI, Kwak JY.
    Clin Cancer Res; 2012 Nov 01; 18(21):5934-48. PubMed ID: 23132899
    [Abstract] [Full Text] [Related]

  • 10. Curcumin mediates ceramide generation via the de novo pathway in colon cancer cells.
    Moussavi M, Assi K, Gómez-Muñoz A, Salh B.
    Carcinogenesis; 2006 Aug 01; 27(8):1636-44. PubMed ID: 16501251
    [Abstract] [Full Text] [Related]

  • 11. Role of c-jun expression increased by heat shock- and ceramide-activated caspase-3 in HL-60 cell apoptosis. Possible involvement of ceramide in heat shock-induced apoptosis.
    Kondo T, Matsuda T, Kitano T, Takahashi A, Tashima M, Ishikura H, Umehara H, Domae N, Uchiyama T, Okazaki T.
    J Biol Chem; 2000 Mar 17; 275(11):7668-76. PubMed ID: 10713077
    [Abstract] [Full Text] [Related]

  • 12. The group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase.
    Lei X, Zhang S, Bohrer A, Bao S, Song H, Ramanadham S.
    Biochemistry; 2007 Sep 04; 46(35):10170-85. PubMed ID: 17685585
    [Abstract] [Full Text] [Related]

  • 13. Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase.
    Mondal S, Mandal C, Sangwan R, Chandra S, Mandal C.
    Mol Cancer; 2010 Sep 13; 9():239. PubMed ID: 20836852
    [Abstract] [Full Text] [Related]

  • 14. Combined treatment of P-gp-positive L1210/VCR cells by verapamil and all-trans retinoic acid induces down-regulation of P-glycoprotein expression and transport activity.
    Sulová Z, Macejová D, Seres M, Sedlák J, Brtko J, Breier A.
    Toxicol In Vitro; 2008 Feb 13; 22(1):96-105. PubMed ID: 17920233
    [Abstract] [Full Text] [Related]

  • 15. Ceramide glycosylation potentiates cellular multidrug resistance.
    Liu YY, Han TY, Giuliano AE, Cabot MC.
    FASEB J; 2001 Mar 13; 15(3):719-30. PubMed ID: 11259390
    [Abstract] [Full Text] [Related]

  • 16. Antimultidrug-resistant effect and mechanism of a novel CA-4 analogue MZ3 on leukemia cells.
    Xu D, Fang L, Zhu Q, Hu Y, He Q, Yang B.
    Pharmazie; 2008 Jul 13; 63(7):528-33. PubMed ID: 18717489
    [Abstract] [Full Text] [Related]

  • 17. Glutathione regulates caspase-dependent ceramide production and curcumin-induced apoptosis in human leukemic cells.
    Kizhakkayil J, Thayyullathil F, Chathoth S, Hago A, Patel M, Galadari S.
    Free Radic Biol Med; 2012 May 01; 52(9):1854-64. PubMed ID: 22387197
    [Abstract] [Full Text] [Related]

  • 18. Synergistic effect of cucurbitacin B in combination with curcumin via enhancing apoptosis induction and reversing multidrug resistance in human hepatoma cells.
    Sun Y, Zhang J, Zhou J, Huang Z, Hu H, Qiao M, Zhao X, Chen D.
    Eur J Pharmacol; 2015 Dec 05; 768():28-40. PubMed ID: 26452516
    [Abstract] [Full Text] [Related]

  • 19. A new apoptosis inhibitor, CIAPIN1 (cytokine-induced apoptosis inhibitor 1), mediates multidrug resistance in leukemia cells by regulating MDR-1, Bcl-2, and Bax.
    Li X, Hong L, Zhao Y, Jin H, Fan R, Du R, Xia L, Luo G, Fan D.
    Biochem Cell Biol; 2007 Dec 05; 85(6):741-50. PubMed ID: 18059532
    [Abstract] [Full Text] [Related]

  • 20. Overexpression of glucosylceramide synthase in associated with multidrug resistance of leukemia cells.
    Xie P, Shen YF, Shi YP, Ge SM, Gu ZH, Wang J, Mu HJ, Zhang B, Qiao WZ, Xie KM.
    Leuk Res; 2008 Mar 05; 32(3):475-80. PubMed ID: 17709137
    [Abstract] [Full Text] [Related]

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