These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

183 related items for PubMed ID: 25254502

  • 1. Binding modes of reverse fosmidomycin analogs toward the antimalarial target IspC.
    Konzuch S, Umeda T, Held J, Hähn S, Brücher K, Lienau C, Behrendt CT, Gräwert T, Bacher A, Illarionov B, Fischer M, Mordmüller B, Tanaka N, Kurz T.
    J Med Chem; 2014 Nov 13; 57(21):8827-38. PubMed ID: 25254502
    [Abstract] [Full Text] [Related]

  • 2. Reverse N-Substituted Hydroxamic Acid Derivatives of Fosmidomycin Target a Previously Unknown Subpocket of 1-Deoxy-d-xylulose 5-Phosphate Reductoisomerase (DXR).
    Abdullaziz MA, Takada S, Illarionov B, Pessanha de Carvalho L, Sakamoto Y, Höfmann S, Knak T, Kiffe-Delf AL, Mazzone F, Pfeffer K, Kalscheuer R, Bacher A, Held J, Fischer M, Tanaka N, Kurz T.
    ACS Infect Dis; 2024 May 10; 10(5):1739-1752. PubMed ID: 38647213
    [Abstract] [Full Text] [Related]

  • 3. Reverse fosmidomycin derivatives against the antimalarial drug target IspC (Dxr).
    Behrendt CT, Kunfermann A, Illarionova V, Matheeussen A, Pein MK, Gräwert T, Kaiser J, Bacher A, Eisenreich W, Illarionov B, Fischer M, Maes L, Groll M, Kurz T.
    J Med Chem; 2011 Oct 13; 54(19):6796-802. PubMed ID: 21866890
    [Abstract] [Full Text] [Related]

  • 4. α-Substituted β-oxa isosteres of fosmidomycin: synthesis and biological evaluation.
    Brücher K, Illarionov B, Held J, Tschan S, Kunfermann A, Pein MK, Bacher A, Gräwert T, Maes L, Mordmüller B, Fischer M, Kurz T.
    J Med Chem; 2012 Jul 26; 55(14):6566-75. PubMed ID: 22731758
    [Abstract] [Full Text] [Related]

  • 5. Evaluation of fosmidomycin analogs as inhibitors of the Synechocystis sp. PCC6803 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
    Woo YH, Fernandes RP, Proteau PJ.
    Bioorg Med Chem; 2006 Apr 01; 14(7):2375-85. PubMed ID: 16310360
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological evaluation of cyclopropyl analogues of fosmidomycin as potent Plasmodium falciparum growth inhibitors.
    Devreux V, Wiesner J, Goeman JL, Van der Eycken J, Jomaa H, Van Calenbergh S.
    J Med Chem; 2006 Apr 20; 49(8):2656-60. PubMed ID: 16610809
    [Abstract] [Full Text] [Related]

  • 7.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 8.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 9. Double ester prodrugs of FR900098 display enhanced in-vitro antimalarial activity.
    Wiesner J, Ortmann R, Jomaa H, Schlitzer M.
    Arch Pharm (Weinheim); 2007 Dec 20; 340(12):667-9. PubMed ID: 17994601
    [Abstract] [Full Text] [Related]

  • 10.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 11. Design, synthesis, and X-ray crystallographic studies of α-aryl substituted fosmidomycin analogues as inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
    Andaloussi M, Henriksson LM, Więckowska A, Lindh M, Björkelid C, Larsson AM, Suresh S, Iyer H, Srinivasa BR, Bergfors T, Unge T, Mowbray SL, Larhed M, Jones TA, Karlén A.
    J Med Chem; 2011 Jul 28; 54(14):4964-76. PubMed ID: 21678907
    [Abstract] [Full Text] [Related]

  • 12.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 13. 1-Deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Mycobacterium tuberculosis: towards understanding mycobacterial resistance to fosmidomycin.
    Dhiman RK, Schaeffer ML, Bailey AM, Testa CA, Scherman H, Crick DC.
    J Bacteriol; 2005 Dec 28; 187(24):8395-402. PubMed ID: 16321944
    [Abstract] [Full Text] [Related]

  • 14. The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation.
    Mac Sweeney A, Lange R, Fernandes RP, Schulz H, Dale GE, Douangamath A, Proteau PJ, Oefner C.
    J Mol Biol; 2005 Jan 07; 345(1):115-27. PubMed ID: 15567415
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and bioactivity of β-substituted fosmidomycin analogues targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
    Chofor R, Sooriyaarachchi S, Risseeuw MD, Bergfors T, Pouyez J, Johny C, Haymond A, Everaert A, Dowd CS, Maes L, Coenye T, Alex A, Couch RD, Jones TA, Wouters J, Mowbray SL, Van Calenbergh S.
    J Med Chem; 2015 Apr 09; 58(7):2988-3001. PubMed ID: 25781377
    [Abstract] [Full Text] [Related]

  • 16.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 17.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 18. Synthesis and antiplasmodial activity of highly active reverse analogues of the antimalarial drug candidate fosmidomycin.
    Behrendt CT, Kunfermann A, Illarionova V, Matheeussen A, Gräwert T, Groll M, Rohdich F, Bacher A, Eisenreich W, Fischer M, Maes L, Kurz T.
    ChemMedChem; 2010 Oct 04; 5(10):1673-6. PubMed ID: 20718073
    [No Abstract] [Full Text] [Related]

  • 19. Synthesis and evaluation of alpha,beta-unsaturated alpha-aryl-substituted fosmidomycin analogues as DXR inhibitors.
    Devreux V, Wiesner J, Jomaa H, Van der Eycken J, Van Calenbergh S.
    Bioorg Med Chem Lett; 2007 Sep 01; 17(17):4920-3. PubMed ID: 17583502
    [Abstract] [Full Text] [Related]

  • 20.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 10.