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Journal Abstract Search

186 related items for PubMed ID: 25260754

  • 1. Targeted transgenesis identifies Gαs as the bottleneck in β2-adrenergic receptor cell signaling and physiological function in airway smooth muscle.
    Wang WC, Pauer SH, Smith DC, Dixon MA, Disimile DJ, Panebra A, An SS, Camoretti-Mercado B, Liggett SB.
    Am J Physiol Lung Cell Mol Physiol; 2014 Nov 15; 307(10):L775-80. PubMed ID: 25260754
    [Abstract] [Full Text] [Related]

  • 2. Paradoxical attenuation of β2-AR function in airway smooth muscle by Gi-mediated counterregulation in transgenic mice overexpressing type 5 adenylyl cyclase.
    Wang WC, Schillinger RM, Malone MM, Liggett SB.
    Am J Physiol Lung Cell Mol Physiol; 2011 Mar 15; 300(3):L472-8. PubMed ID: 21131397
    [Abstract] [Full Text] [Related]

  • 3. Targeted transgenesis reveals discrete attenuator functions of GRK and PKA in airway beta2-adrenergic receptor physiologic signaling.
    Wang WC, Mihlbachler KA, Brunnett AC, Liggett SB.
    Proc Natl Acad Sci U S A; 2009 Sep 01; 106(35):15007-12. PubMed ID: 19706446
    [Abstract] [Full Text] [Related]

  • 4. Mechanism regulating proasthmatic effects of prolonged homologous beta2-adrenergic receptor desensitization in airway smooth muscle.
    Nino G, Hu A, Grunstein JS, Grunstein MM.
    Am J Physiol Lung Cell Mol Physiol; 2009 Oct 01; 297(4):L746-57. PubMed ID: 19666775
    [Abstract] [Full Text] [Related]

  • 5. β2-Adrenergic Receptors Chaperone Trapped Bitter Taste Receptor 14 to the Cell Surface as a Heterodimer and Exert Unidirectional Desensitization of Taste Receptor Function.
    Kim D, Pauer SH, Yong HM, An SS, Liggett SB.
    J Biol Chem; 2016 Aug 19; 291(34):17616-28. PubMed ID: 27342779
    [Abstract] [Full Text] [Related]

  • 6. TAS2R activation promotes airway smooth muscle relaxation despite β(2)-adrenergic receptor tachyphylaxis.
    An SS, Wang WC, Koziol-White CJ, Ahn K, Lee DY, Kurten RC, Panettieri RA, Liggett SB.
    Am J Physiol Lung Cell Mol Physiol; 2012 Aug 15; 303(4):L304-11. PubMed ID: 22683571
    [Abstract] [Full Text] [Related]

  • 7. Bitter taste receptors in the wrong place: novel airway smooth muscle targets for treating asthma.
    Liggett SB.
    Trans Am Clin Climatol Assoc; 2014 Aug 15; 125():64-74; discussion 74-5. PubMed ID: 25125719
    [Abstract] [Full Text] [Related]

  • 8. β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D.
    Trian T, Burgess JK, Niimi K, Moir LM, Ge Q, Berger P, Liggett SB, Black JL, Oliver BG.
    PLoS One; 2011 Aug 15; 6(5):e20000. PubMed ID: 21611147
    [Abstract] [Full Text] [Related]

  • 9. Identification and characterization of an atypical Gαs-biased β2AR agonist that fails to evoke airway smooth muscle cell tachyphylaxis.
    Kim D, Tokmakova A, Lujan LK, Strzelinski HR, Kim N, Najari Beidokhti M, Giulianotti MA, Mafi A, Woo JA, An SS, Goddard WA, Liggett SB.
    Proc Natl Acad Sci U S A; 2021 Dec 07; 118(49):. PubMed ID: 34857633
    [Abstract] [Full Text] [Related]

  • 10. A CREB-mediated increase in miRNA let-7f during prolonged β-agonist exposure: a novel mechanism of β2-adrenergic receptor down-regulation in airway smooth muscle.
    Kim D, Cho S, Woo JA, Liggett SB.
    FASEB J; 2018 Jul 07; 32(7):3680-3688. PubMed ID: 29455573
    [Abstract] [Full Text] [Related]

  • 11. Transgenic overexpression of beta(2)-adrenergic receptors in airway smooth muscle alters myocyte function and ablates bronchial hyperreactivity.
    McGraw DW, Forbes SL, Kramer LA, Witte DP, Fortner CN, Paul RJ, Liggett SB.
    J Biol Chem; 1999 Nov 05; 274(45):32241-7. PubMed ID: 10542262
    [Abstract] [Full Text] [Related]

  • 12. The dopamine D1 receptor is expressed and facilitates relaxation in airway smooth muscle.
    Mizuta K, Zhang Y, Xu D, Mizuta F, D'Ovidio F, Masaki E, Emala CW.
    Respir Res; 2013 Sep 02; 14(1):89. PubMed ID: 24004608
    [Abstract] [Full Text] [Related]

  • 13. Hyperinsulinemia promotes heterologous desensitization of β2 adrenergic receptor in airway smooth muscle in obesity.
    Xu R, Gopireddy RR, Wu Y, Wu L, Tao X, Shao J, Wang W, Li L, Jovanovic A, Xu B, Kenyon NJ, Lu Q, Xiang YK, Fu Q.
    FASEB J; 2020 Mar 02; 34(3):3996-4008. PubMed ID: 31960515
    [Abstract] [Full Text] [Related]

  • 14. Inflammatory and contractile agents sensitize specific adenylyl cyclase isoforms in human airway smooth muscle.
    Billington CK, Hall IP, Mundell SJ, Parent JL, Panettieri RA, Benovic JL, Penn RB.
    Am J Respir Cell Mol Biol; 1999 Nov 02; 21(5):597-606. PubMed ID: 10536119
    [Abstract] [Full Text] [Related]

  • 15. Antimitogenic effect of bitter taste receptor agonists on airway smooth muscle cells.
    Sharma P, Panebra A, Pera T, Tiegs BC, Hershfeld A, Kenyon LC, Deshpande DA.
    Am J Physiol Lung Cell Mol Physiol; 2016 Feb 15; 310(4):L365-76. PubMed ID: 26684251
    [Abstract] [Full Text] [Related]

  • 16. Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity.
    Tan X, Sanderson MJ.
    Br J Pharmacol; 2014 Feb 15; 171(3):646-62. PubMed ID: 24117140
    [Abstract] [Full Text] [Related]

  • 17. Prolonged heterologous beta2-adrenoceptor desensitization promotes proasthmatic airway smooth muscle function via PKA/ERK1/2-mediated phosphodiesterase-4 induction.
    Hu A, Nino G, Grunstein JS, Fatma S, Grunstein MM.
    Am J Physiol Lung Cell Mol Physiol; 2008 Jun 15; 294(6):L1055-67. PubMed ID: 18359889
    [Abstract] [Full Text] [Related]

  • 18. Heat Shock-Related Protein 20 Peptide Decreases Human Airway Constriction Downstream of β2-Adrenergic Receptor.
    Banathy A, Cheung-Flynn J, Goleniewska K, Boyd KL, Newcomb DC, Peebles RS, Komalavilas P.
    Am J Respir Cell Mol Biol; 2016 Aug 15; 55(2):225-33. PubMed ID: 26909644
    [Abstract] [Full Text] [Related]

  • 19. Airway smooth muscle prostaglandin-EP1 receptors directly modulate beta2-adrenergic receptors within a unique heterodimeric complex.
    McGraw DW, Mihlbachler KA, Schwarb MR, Rahman FF, Small KM, Almoosa KF, Liggett SB.
    J Clin Invest; 2006 May 15; 116(5):1400-9. PubMed ID: 16670773
    [Abstract] [Full Text] [Related]

  • 20. Exploiting functional domains of GRK2/3 to alter the competitive balance of pro- and anticontractile signaling in airway smooth muscle.
    Deshpande DA, Yan H, Kong KC, Tiegs BC, Morgan SJ, Pera T, Panettieri RA, Eckhart AD, Penn RB.
    FASEB J; 2014 Feb 15; 28(2):956-65. PubMed ID: 24132623
    [Abstract] [Full Text] [Related]

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