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Journal Abstract Search

137 related items for PubMed ID: 25264323

  • 1. Protected hinge in the immunoglobulin G2-A2 disulfide isoform.
    Liu YD, Chou RY, Dillon TM, Poppe L, Spahr C, Shi SD, Flynn GC.
    Protein Sci; 2014 Dec; 23(12):1753-64. PubMed ID: 25264323
    [Abstract] [Full Text] [Related]

  • 2. Conformational difference in human IgG2 disulfide isoforms revealed by hydrogen/deuterium exchange mass spectrometry.
    Zhang A, Fang J, Chou RY, Bondarenko PV, Zhang Z.
    Biochemistry; 2015 Mar 17; 54(10):1956-62. PubMed ID: 25730439
    [Abstract] [Full Text] [Related]

  • 3. IgG2 disulfide isoform conversion kinetics.
    Liu YD, Wang T, Chou R, Chen L, Kannan G, Stevenson R, Goetze AM, Jiang XG, Huang G, Dillon TM, Flynn GC.
    Mol Immunol; 2013 Jun 17; 54(2):217-26. PubMed ID: 23291144
    [Abstract] [Full Text] [Related]

  • 4. Human IgG2 antibodies display disulfide-mediated structural isoforms.
    Wypych J, Li M, Guo A, Zhang Z, Martinez T, Allen MJ, Fodor S, Kelner DN, Flynn GC, Liu YD, Bondarenko PV, Ricci MS, Dillon TM, Balland A.
    J Biol Chem; 2008 Jun 06; 283(23):16194-205. PubMed ID: 18339624
    [Abstract] [Full Text] [Related]

  • 5. Determination of Fab-hinge disulfide connectivity in structural isoforms of a recombinant human immunoglobulin G2 antibody.
    Zhang B, Harder AG, Connelly HM, Maheu LL, Cockrill SL.
    Anal Chem; 2010 Feb 01; 82(3):1090-9. PubMed ID: 20039682
    [Abstract] [Full Text] [Related]

  • 6. Disulfide connectivity of human immunoglobulin G2 structural isoforms.
    Martinez T, Guo A, Allen MJ, Han M, Pace D, Jones J, Gillespie R, Ketchem RR, Zhang Y, Balland A.
    Biochemistry; 2008 Jul 15; 47(28):7496-508. PubMed ID: 18549248
    [Abstract] [Full Text] [Related]

  • 7. Disulfide scrambling in IgG2 monoclonal antibodies: insights from molecular dynamics simulations.
    Wang X, Kumar S, Singh SK.
    Pharm Res; 2011 Dec 15; 28(12):3128-44. PubMed ID: 21671135
    [Abstract] [Full Text] [Related]

  • 8. Structural and functional characterization of disulfide isoforms of the human IgG2 subclass.
    Dillon TM, Ricci MS, Vezina C, Flynn GC, Liu YD, Rehder DS, Plant M, Henkle B, Li Y, Deechongkit S, Varnum B, Wypych J, Balland A, Bondarenko PV.
    J Biol Chem; 2008 Jun 06; 283(23):16206-15. PubMed ID: 18339626
    [Abstract] [Full Text] [Related]

  • 9. Rapid, automated characterization of disulfide bond scrambling and IgG2 isoform determination.
    Resemann A, Liu-Shin L, Tremintin G, Malhotra A, Fung A, Wang F, Ratnaswamy G, Suckau D.
    MAbs; 2018 Jun 06; 10(8):1200-1213. PubMed ID: 30277844
    [Abstract] [Full Text] [Related]

  • 10. Influence of disulfide bond isoforms on drug conjugation sites in cysteine-linked IgG2 antibody-drug conjugates.
    Liu-Shin L, Fung A, Malhotra A, Ratnaswamy G.
    MAbs; 2018 Jun 06; 10(4):583-595. PubMed ID: 29436897
    [Abstract] [Full Text] [Related]

  • 11. Characterization of disulfide linkages at the hinge region of IgG antibodies by HPLC mass spectrometry.
    You J, Shi Y, Zhu W, Wu Z, Xiong J.
    Biomed Chromatogr; 2018 Dec 06; 32(12):e4371. PubMed ID: 30121965
    [Abstract] [Full Text] [Related]

  • 12. Characterization of cysteine related variants in an IgG2 antibody by LC-MS with an automated data analysis approach.
    Zhang Y, Bailey R, Nightlinger N, Gillespie A, Balland A, Rogers R.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2015 Aug 01; 997():30-7. PubMed ID: 26079266
    [Abstract] [Full Text] [Related]

  • 13. Disulfide bond structures of IgG molecules: structural variations, chemical modifications and possible impacts to stability and biological function.
    Liu H, May K.
    MAbs; 2012 Aug 01; 4(1):17-23. PubMed ID: 22327427
    [Abstract] [Full Text] [Related]

  • 14. Human Fc receptor-like 5 distinguishes IgG2 disulfide isoforms and deamidated charge variants.
    Alabi O, Dement-Brown J, Tolnay M.
    Mol Immunol; 2017 Dec 01; 92():161-168. PubMed ID: 29101848
    [Abstract] [Full Text] [Related]

  • 15. Evidence of disulfide bond scrambling during production of an antibody-drug conjugate.
    Liu-Shin LP, Fung A, Malhotra A, Ratnaswamy G.
    MAbs; 2018 Dec 01; 10(8):1190-1199. PubMed ID: 30339473
    [Abstract] [Full Text] [Related]

  • 16. Intrachain disulfide bond in the core hinge region of human IgG4.
    Bloom JW, Madanat MS, Marriott D, Wong T, Chan SY.
    Protein Sci; 1997 Feb 01; 6(2):407-15. PubMed ID: 9041643
    [Abstract] [Full Text] [Related]

  • 17. Interchain disulfide bonding in human IgG2 antibodies probed by site-directed mutagenesis.
    Allen MJ, Guo A, Martinez T, Han M, Flynn GC, Wypych J, Liu YD, Shen WD, Dillon TM, Vezina C, Balland A.
    Biochemistry; 2009 May 05; 48(17):3755-66. PubMed ID: 19254029
    [Abstract] [Full Text] [Related]

  • 18. Alleviating nonlinear behavior of disulfide isoforms in the reversed-phase liquid chromatography of IgG2.
    Cao X, He Y, Smith J, Wirth MJ.
    J Chromatogr A; 2015 Sep 04; 1410():147-53. PubMed ID: 26256919
    [Abstract] [Full Text] [Related]

  • 19. Resolving disulfide structural isoforms of IgG2 monoclonal antibodies by ion mobility mass spectrometry.
    Bagal D, Valliere-Douglass JF, Balland A, Schnier PD.
    Anal Chem; 2010 Aug 15; 82(16):6751-5. PubMed ID: 20704363
    [Abstract] [Full Text] [Related]

  • 20. Impact of antibody subclass and disulfide isoform differences on the biological activity of CD200R and βklotho agonist antibodies.
    Grujic O, Stevens J, Chou RY, Weiszmann JV, Sekirov L, Thomson C, Badh A, Grauer S, Chan B, Graham K, Manchulenko K, Dillon TM, Li Y, Foltz IN.
    Biochem Biophys Res Commun; 2017 May 13; 486(4):985-991. PubMed ID: 28363871
    [Abstract] [Full Text] [Related]

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