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406 related items for PubMed ID: 25265063

  • 1. Insulin upregulates the expression of epithelial sodium channel in vitro and in a mouse model of acute lung injury: role of mTORC2/SGK1 pathway.
    He J, Qi D, Wang DX, Deng W, Ye Y, Feng LH, Zhu T, Zhao Y, Zhang CR.
    Exp Cell Res; 2015 Feb 01; 331(1):164-175. PubMed ID: 25265063
    [Abstract] [Full Text] [Related]

  • 2. Regulation of ENaC-mediated alveolar fluid clearance by insulin via PI3K/Akt pathway in LPS-induced acute lung injury.
    Deng W, Li CY, Tong J, Zhang W, Wang DX.
    Respir Res; 2012 Mar 30; 13(1):29. PubMed ID: 22458687
    [Abstract] [Full Text] [Related]

  • 3. 17β-estradiol suppresses lipopolysaccharide-induced acute lung injury through PI3K/Akt/SGK1 mediated up-regulation of epithelial sodium channel (ENaC) in vivo and in vitro.
    Qi D, He J, Wang D, Deng W, Zhao Y, Ye Y, Feng L.
    Respir Res; 2014 Dec 31; 15(1):159. PubMed ID: 25551628
    [Abstract] [Full Text] [Related]

  • 4. Rosiglitazone promotes ENaC-mediated alveolar fluid clearance in acute lung injury through the PPARγ/SGK1 signaling pathway.
    He J, Qi D, Tang XM, Deng W, Deng XY, Zhao Y, Wang DX.
    Cell Mol Biol Lett; 2019 Dec 31; 24():35. PubMed ID: 31160894
    [Abstract] [Full Text] [Related]

  • 5. Regulation of the epithelial Na+ channel by the mTORC2/SGK1 pathway.
    Lang F, Pearce D.
    Nephrol Dial Transplant; 2016 Feb 31; 31(2):200-5. PubMed ID: 26163195
    [Abstract] [Full Text] [Related]

  • 6. Insulin ameliorates pulmonary edema through the upregulation of epithelial sodium channel via the PI3K/SGK1 pathway in mice with lipopolysaccharide‑induced lung injury.
    Deng W, Li CY, Tong J, He J, Zhao Y, Wang DX.
    Mol Med Rep; 2019 Mar 31; 19(3):1665-1677. PubMed ID: 30628684
    [Abstract] [Full Text] [Related]

  • 7. Insulin up-regulates epithelial sodium channel in LPS-induced acute lung injury model in rats by SGK1 activation.
    Zhu T, Zhang W, Wang DX.
    Injury; 2012 Aug 31; 43(8):1277-83. PubMed ID: 22552040
    [Abstract] [Full Text] [Related]

  • 8. mTOR complex-2 activates ENaC by phosphorylating SGK1.
    Lu M, Wang J, Jones KT, Ives HE, Feldman ME, Yao LJ, Shokat KM, Ashrafi K, Pearce D.
    J Am Soc Nephrol; 2010 May 31; 21(5):811-8. PubMed ID: 20338997
    [Abstract] [Full Text] [Related]

  • 9. Adenosine A2B receptor activation stimulates alveolar fluid clearance through alveolar epithelial sodium channel via cAMP pathway in endotoxin-induced lung injury.
    Wang M, Guo X, Zhao H, Lv J, Wang H, An Y.
    Am J Physiol Lung Cell Mol Physiol; 2020 Apr 01; 318(4):L787-L800. PubMed ID: 32129084
    [Abstract] [Full Text] [Related]

  • 10. PCTR1 improves pulmonary edema fluid clearance through activating the sodium channel and lymphatic drainage in lipopolysaccharide-induced ARDS.
    Zhang PH, Han J, Cao F, Liu YJ, Tian C, Wu CH, Smith FG, Hao Y, Jin SW.
    J Cell Physiol; 2020 Dec 01; 235(12):9510-9523. PubMed ID: 32529661
    [Abstract] [Full Text] [Related]

  • 11. Aldosterone alleviates lipopolysaccharide-induced acute lung injury by regulating epithelial sodium channel through PI3K/Akt/SGK1 signaling pathway.
    Fei X, Ziqian Y, Bingwu Y, Min L, Xinmiao X, Zhen M, Lirong G, Song W.
    Mol Cell Probes; 2021 Jun 01; 57():101709. PubMed ID: 33713776
    [Abstract] [Full Text] [Related]

  • 12. Maresin1 stimulates alveolar fluid clearance through the alveolar epithelial sodium channel Na,K-ATPase via the ALX/PI3K/Nedd4-2 pathway.
    Zhang JL, Zhuo XJ, Lin J, Luo LC, Ying WY, Xie X, Zhang HW, Yang JX, Li D, Gao Smith F, Jin SW.
    Lab Invest; 2017 May 01; 97(5):543-554. PubMed ID: 28218740
    [Abstract] [Full Text] [Related]

  • 13. mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity.
    Gleason CE, Frindt G, Cheng CJ, Ng M, Kidwai A, Rashmi P, Lang F, Baum M, Palmer LG, Pearce D.
    J Clin Invest; 2015 Jan 01; 125(1):117-28. PubMed ID: 25415435
    [Abstract] [Full Text] [Related]

  • 14. mSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel.
    Lu M, Wang J, Ives HE, Pearce D.
    J Biol Chem; 2011 Sep 02; 286(35):30647-30654. PubMed ID: 21757730
    [Abstract] [Full Text] [Related]

  • 15. Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression.
    Hall BA, Kim TY, Skor MN, Conzen SD.
    Breast Cancer Res Treat; 2012 Sep 02; 135(2):469-79. PubMed ID: 22842983
    [Abstract] [Full Text] [Related]

  • 16. Potassium Activates mTORC2-dependent SGK1 Phosphorylation to Stimulate Epithelial Sodium Channel: Role in Rapid Renal Responses to Dietary Potassium.
    Saha B, Shabbir W, Takagi E, Duan XP, Leite Dellova DCA, Demko J, Manis A, Loffing-Cueni D, Loffing J, Sørensen MV, Wang WH, Pearce D.
    J Am Soc Nephrol; 2023 Jun 01; 34(6):1019-1038. PubMed ID: 36890646
    [Abstract] [Full Text] [Related]

  • 17. WNK1 is a chloride-stimulated scaffold that regulates mTORC2 activity and ion transport.
    Saha B, Leite-Dellova DCA, Demko J, Sørensen MV, Takagi E, Gleason CE, Shabbir W, Pearce D.
    J Cell Sci; 2022 Dec 01; 135(23):. PubMed ID: 36373794
    [Abstract] [Full Text] [Related]

  • 18. Acute Hyperglycemia Aggravates Lung Injury via Activation of the SGK1-NKCC1 Pathway.
    Wu CP, Huang KL, Peng CK, Lan CC.
    Int J Mol Sci; 2020 Jul 07; 21(13):. PubMed ID: 32645929
    [Abstract] [Full Text] [Related]

  • 19. LEFTYA Activates the Epithelial Na+ Channel (ENaC) in Endometrial Cells via Serum and Glucocorticoid Inducible Kinase SGK1.
    Salker MS, Hosseinzadeh Z, Alowayed N, Zeng N, Umbach AT, Webster Z, Singh Y, Brosens JJ, Lang F.
    Cell Physiol Biochem; 2016 Jul 07; 39(4):1295-306. PubMed ID: 27606670
    [Abstract] [Full Text] [Related]

  • 20. mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
    García-Martínez JM, Alessi DR.
    Biochem J; 2008 Dec 15; 416(3):375-85. PubMed ID: 18925875
    [Abstract] [Full Text] [Related]

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