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315 related items for PubMed ID: 25281698

  • 1. N-acetylgalactosaminide α2,6-sialyltransferase II is a candidate enzyme for sialylation of galactose-deficient IgA1, the key autoantigen in IgA nephropathy.
    Stuchlova Horynova M, Vrablikova A, Stewart TJ, Takahashi K, Czernekova L, Yamada K, Suzuki H, Julian BA, Renfrow MB, Novak J, Raska M.
    Nephrol Dial Transplant; 2015 Feb; 30(2):234-8. PubMed ID: 25281698
    [Abstract] [Full Text] [Related]

  • 2. Enzymatic sialylation of IgA1 O-glycans: implications for studies of IgA nephropathy.
    Takahashi K, Raska M, Stuchlova Horynova M, Hall SD, Poulsen K, Kilian M, Hiki Y, Yuzawa Y, Moldoveanu Z, Julian BA, Renfrow MB, Novak J.
    PLoS One; 2014 Feb; 9(2):e99026. PubMed ID: 24918438
    [Abstract] [Full Text] [Related]

  • 3. IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1.
    Suzuki H, Moldoveanu Z, Hall S, Brown R, Vu HL, Novak L, Julian BA, Tomana M, Wyatt RJ, Edberg JC, Alarcón GS, Kimberly RP, Tomino Y, Mestecky J, Novak J.
    J Clin Invest; 2008 Feb; 118(2):629-39. PubMed ID: 18172551
    [Abstract] [Full Text] [Related]

  • 4. Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes.
    Suzuki H, Raska M, Yamada K, Moldoveanu Z, Julian BA, Wyatt RJ, Tomino Y, Gharavi AG, Novak J.
    J Biol Chem; 2014 Feb 21; 289(8):5330-9. PubMed ID: 24398680
    [Abstract] [Full Text] [Related]

  • 5. Elucidating heterogeneity of IgA1 hinge-region O-glycosylation by use of MALDI-TOF/TOF mass spectrometry: role of cysteine alkylation during sample processing.
    Franc V, Řehulka P, Raus M, Stulík J, Novak J, Renfrow MB, Šebela M.
    J Proteomics; 2013 Oct 30; 92():299-312. PubMed ID: 23891555
    [Abstract] [Full Text] [Related]

  • 6. O- and N-Glycosylation of Serum Immunoglobulin A is Associated with IgA Nephropathy and Glomerular Function.
    Dotz V, Visconti A, Lomax-Browne HJ, Clerc F, Hipgrave Ederveen AL, Medjeral-Thomas NR, Cook HT, Pickering MC, Wuhrer M, Falchi M.
    J Am Soc Nephrol; 2021 Oct 30; 32(10):2455-2465. PubMed ID: 34127537
    [Abstract] [Full Text] [Related]

  • 7. Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies.
    Tomana M, Novak J, Julian BA, Matousovic K, Konecny K, Mestecky J.
    J Clin Invest; 1999 Jul 30; 104(1):73-81. PubMed ID: 10393701
    [Abstract] [Full Text] [Related]

  • 8. Recognition of galactose-deficient O-glycans in the hinge region of IgA1 by N-acetylgalactosamine-specific snail lectins: a comparative binding study.
    Gomes MM, Suzuki H, Brooks MT, Tomana M, Moldoveanu Z, Mestecky J, Julian BA, Novak J, Herr AB.
    Biochemistry; 2010 Jul 13; 49(27):5671-82. PubMed ID: 20507092
    [Abstract] [Full Text] [Related]

  • 9. Aberrantly glycosylated serum IgA1 are closely associated with pathologic phenotypes of IgA nephropathy.
    Xu LX, Zhao MH.
    Kidney Int; 2005 Jul 13; 68(1):167-72. PubMed ID: 15954905
    [Abstract] [Full Text] [Related]

  • 10. Increased sialylation of polymeric immunoglobulin A1: mechanism of selective glomerular deposition in immunoglobulin A nephropathy?
    Leung JC, Poon PY, Lai KN.
    J Lab Clin Med; 1999 Feb 13; 133(2):152-60. PubMed ID: 9989767
    [Abstract] [Full Text] [Related]

  • 11. The glycans deficiencies of macromolecular IgA1 is a contributory factor of variable pathological phenotypes of IgA nephropathy.
    Xu LX, Yan Y, Zhang JJ, Zhang Y, Zhao MH.
    Clin Exp Immunol; 2005 Dec 13; 142(3):569-75. PubMed ID: 16297170
    [Abstract] [Full Text] [Related]

  • 12. Identification and characterization of CMP-NeuAc:GalNAc-IgA1 alpha2,6-sialyltransferase in IgA1-producing cells.
    Raska M, Moldoveanu Z, Suzuki H, Brown R, Kulhavy R, Andrasi J, Hall S, Vu HL, Carlsson F, Lindahl G, Tomana M, Julian BA, Wyatt RJ, Mestecky J, Novak J.
    J Mol Biol; 2007 May 25; 369(1):69-78. PubMed ID: 17418236
    [Abstract] [Full Text] [Related]

  • 13. IgA nephropathy: characterization of IgG antibodies specific for galactose-deficient IgA1.
    Suzuki H, Moldoveanu Z, Hall S, Brown R, Julian BA, Wyatt RJ, Tomana M, Tomino Y, Novak J, Mestecky J.
    Contrib Nephrol; 2007 May 25; 157():129-33. PubMed ID: 17495450
    [Abstract] [Full Text] [Related]

  • 14. Role of aberrant glycosylation of IgA1 molecules in the pathogenesis of IgA nephropathy.
    Mestecky J, Tomana M, Moldoveanu Z, Julian BA, Suzuki H, Matousovic K, Renfrow MB, Novak L, Wyatt RJ, Novak J.
    Kidney Blood Press Res; 2008 May 25; 31(1):29-37. PubMed ID: 18182777
    [Abstract] [Full Text] [Related]

  • 15. Sialylation of IgG inhibits the formation of galactose-deficient IgA1-containing immune complexes and protects mesangial cells from injury in IgA nephropathy.
    Liu Y, Li H, Yu H, Wang F, Jia J, Yan T.
    BMC Nephrol; 2022 Jan 11; 23(1):25. PubMed ID: 35016642
    [Abstract] [Full Text] [Related]

  • 16. Analysis of O-glycoforms of the IgA1 hinge region by sequential deglycosylation.
    Ohyama Y, Yamaguchi H, Nakajima K, Mizuno T, Fukamachi Y, Yokoi Y, Tsuboi N, Inaguma D, Hasegawa M, Renfrow MB, Novak J, Yuzawa Y, Takahashi K.
    Sci Rep; 2020 Jan 20; 10(1):671. PubMed ID: 31959827
    [Abstract] [Full Text] [Related]

  • 17. GalNAc-T14 may Contribute to Production of Galactose-Deficient Immunoglobulin A1, the Main Autoantigen in IgA Nephropathy.
    Jemelkova J, Stuchlova Horynova M, Kosztyu P, Zachova K, Zadrazil J, Galuszkova D, Takahashi K, Novak J, Raska M.
    Kidney Int Rep; 2023 May 20; 8(5):1068-1075. PubMed ID: 37180502
    [Abstract] [Full Text] [Related]

  • 18. Activity of alpha2,6-sialyltransferase and its gene expression in peripheral B lymphocytes in patients with IgA nephropathy.
    Ding JX, Xu LX, Zhu L, Lv JC, Zhao MH, Zhang H, Wang HY.
    Scand J Immunol; 2009 Feb 20; 69(2):174-80. PubMed ID: 19170967
    [Abstract] [Full Text] [Related]

  • 19. Increased sialylation of polymeric lambda-IgA1 in patients with IgA nephropathy.
    Leung JC, Tang SC, Chan DT, Lui SL, Lai KN.
    J Clin Lab Anal; 2002 Feb 20; 16(1):11-9. PubMed ID: 11835525
    [Abstract] [Full Text] [Related]

  • 20. Galactose-Deficient IgA1-Specific Antibody Recognizes GalNAc-Modified Unique Epitope on Hinge Region of IgA1.
    Yamasaki K, Suzuki H, Yasutake J, Yamazaki Y, Suzuki Y.
    Monoclon Antib Immunodiagn Immunother; 2018 Dec 20; 37(6):252-256. PubMed ID: 30570353
    [Abstract] [Full Text] [Related]

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