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227 related items for PubMed ID: 25282651
1. SAR analysis and biological studies of synthesized podophyllum derivates obtained by N linkage modification at C-4 position. Wang H, Tang L, Tang Y, Yuan Z. Bioorg Med Chem; 2014 Nov 01; 22(21):6183-92. PubMed ID: 25282651 [Abstract] [Full Text] [Related]
2. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation. Zhao W, Chen L, Li HM, Wang DJ, Li DS, Chen T, Yuan ZP, Tang YJ. Bioorg Med Chem; 2014 Jun 01; 22(11):2998-3007. PubMed ID: 24775914 [Abstract] [Full Text] [Related]
3. Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers. Kamal A, Tamboli JR, Nayak VL, Adil SF, Vishnuvardhan MV, Ramakrishna S. Bioorg Med Chem; 2014 May 01; 22(9):2714-23. PubMed ID: 24721832 [Abstract] [Full Text] [Related]
4. Synthesis and evaluation of the cell cycle arrest and CT DNA interaction properties of 4β-amino-4'-O-demethyl-4-deoxypodophyllotoxins. Liu JF, Sang CY, Qin WW, Zhao J, Hui L, Ding YL, Chen SW. Bioorg Med Chem; 2013 Nov 15; 21(22):6948-55. PubMed ID: 24095019 [Abstract] [Full Text] [Related]
10. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents. Liu Y, Wei D, Zhao Y, Cheng W, Lu Y, Ma Y, Li X, Han C, Wei Y, Cao H, Zhao C. Bioorg Med Chem; 2012 Nov 01; 20(21):6285-95. PubMed ID: 23022053 [Abstract] [Full Text] [Related]
12. Investigation of podophyllotoxin esters as potential anticancer agents: synthesis, biological studies and tubulin inhibition properties. Shareef MA, Duscharla D, Ramasatyaveni G, Dhoke NR, Das A, Ummanni R, Srivastava AK. Eur J Med Chem; 2015 Jan 07; 89():128-37. PubMed ID: 25462233 [Abstract] [Full Text] [Related]
13. Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents. Wang ZZ, Sun WX, Wang X, Zhang YH, Qiu HY, Qi JL, Pang YJ, Lu GH, Wang XM, Yu FG, Yang YH. Chem Biol Drug Des; 2017 Aug 07; 90(2):236-243. PubMed ID: 28079286 [Abstract] [Full Text] [Related]
14. Design, synthesis, and antitumor activity of novel podophyllotoxin derivatives as potent anticancer agents. Liu J, Cao B, Gao Y, Bai M, Mei X, Chen H, Jiang YG, Huang DJ. J Asian Nat Prod Res; 2013 Sep 07; 15(9):985-92. PubMed ID: 23859462 [Abstract] [Full Text] [Related]
15. Comparison of carbon-sulfur and carbon-amine bond in therapeutic drug: 4β-S-aromatic heterocyclic podophyllum derivatives display antitumor activity. Li JL, Zhao W, Zhou C, Zhang YX, Li HM, Tang YL, Liang XH, Chen T, Tang YJ. Sci Rep; 2015 Oct 07; 5():14814. PubMed ID: 26443888 [Abstract] [Full Text] [Related]
19. Synthesis and biological evaluation of 4β-sulphonamido and 4β-[(4'-sulphonamido)benzamide]podophyllotoxins as DNA topoisomerase-IIα and apoptosis inducing agents. Kamal A, Suresh P, Ramaiah MJ, Mallareddy A, Imthiajali S, Pushpavalli SN, Lavanya A, Pal-Bhadra M. Bioorg Med Chem; 2012 Mar 15; 20(6):2054-66. PubMed ID: 22364746 [Abstract] [Full Text] [Related]