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PUBMED FOR HANDHELDS

Journal Abstract Search

139 related items for PubMed ID: 25286150

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  • 23. Design and synthesis of novel pyrimido[5,4-d]pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes.
    Fang Y, Xu J, Li Z, Yang Z, Xiong L, Jin Y, Wang Q, Xie S, Zhu W, Chang S.
    Bioorg Med Chem; 2018 Aug 07; 26(14):4080-4087. PubMed ID: 30100020
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  • 24. Discovery of a novel series of indolinylpyrimidine-based GPR119 agonists: Elimination of ether-a-go-go-related gene liability using a hydrogen bond acceptor-focused approach.
    Kamaura M, Kubo O, Sugimoto H, Noguchi N, Miyashita H, Abe S, Matsuda K, Tsujihata Y, Odani T, Iwasaki S, Murata T, Sato K.
    Bioorg Med Chem; 2021 Mar 15; 34():116034. PubMed ID: 33548803
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  • 25. Discovery of a nortropanol derivative as a potent and orally active GPR119 agonist for type 2 diabetes.
    Xia Y, Chackalamannil S, Greenlee WJ, Jayne C, Neustadt B, Stamford A, Vaccaro H, Xu XL, Baker H, O'Neill K, Woods M, Hawes B, Kowalski T.
    Bioorg Med Chem Lett; 2011 Jun 01; 21(11):3290-6. PubMed ID: 21536438
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  • 28. Synthesis and biological evaluation of 1, 2, 4-oxadiazole derivatives as novel GPR119 agonists.
    Fu S, Xiang W, Chen J, Ma L, Chen L.
    Chem Biol Drug Des; 2017 May 01; 89(5):815-819. PubMed ID: 27779815
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  • 29. GPR119 agonists for the treatment of type 2 diabetes.
    Jones RM, Leonard JN, Buzard DJ, Lehmann J.
    Expert Opin Ther Pat; 2009 Oct 01; 19(10):1339-59. PubMed ID: 19780700
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  • 32. Conformational restriction in a series of GPR119 agonists: differences in pharmacology between mouse and human.
    Scott JS, Brocklehurst KJ, Brown HS, Clarke DS, Coe H, Groombridge SD, Laber D, MacFaul PA, McKerrecher D, Schofield P.
    Bioorg Med Chem Lett; 2013 Jun 01; 23(11):3175-9. PubMed ID: 23628336
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  • 33. Synthesis and biological evaluation of 5-nitropyrimidine analogs with azabicyclic substituents as GPR119 agonists.
    Yang Z, Fang Y, Pham TA, Lee J, Park H.
    Bioorg Med Chem Lett; 2013 Mar 01; 23(5):1519-21. PubMed ID: 23374864
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  • 34. Optimization of oxadiazole derivatives with a spirocyclic cyclohexane structure as novel GPR119 agonists.
    Harada K, Mizukami J, Watanabe T, Mori G, Ubukata M, Suwa K, Fukuda S, Negoro T, Sato M, Inaba T.
    Bioorg Med Chem Lett; 2019 Aug 15; 29(16):2100-2106. PubMed ID: 31288965
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