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532 related items for PubMed ID: 25297997

  • 1. Recombinant modified vaccinia virus Ankara generating excess early double-stranded RNA transiently activates protein kinase R and triggers enhanced innate immune responses.
    Wolferstätter M, Schweneker M, Späth M, Lukassen S, Klingenberg M, Brinkmann K, Wielert U, Lauterbach H, Hochrein H, Chaplin P, Suter M, Hausmann J.
    J Virol; 2014 Dec; 88(24):14396-411. PubMed ID: 25297997
    [Abstract] [Full Text] [Related]

  • 2. Opposing Roles of Double-Stranded RNA Effector Pathways and Viral Defense Proteins Revealed with CRISPR-Cas9 Knockout Cell Lines and Vaccinia Virus Mutants.
    Liu R, Moss B.
    J Virol; 2016 Sep 01; 90(17):7864-79. PubMed ID: 27334583
    [Abstract] [Full Text] [Related]

  • 3. Double-stranded RNA-binding protein E3 controls translation of viral intermediate RNA, marking an essential step in the life cycle of modified vaccinia virus Ankara.
    Ludwig H, Suezer Y, Waibler Z, Kalinke U, Schnierle BS, Sutter G.
    J Gen Virol; 2006 May 01; 87(Pt 5):1145-1155. PubMed ID: 16603515
    [Abstract] [Full Text] [Related]

  • 4. Viral double-stranded RNAs from vaccinia virus early or intermediate gene transcripts possess PKR activating function, resulting in NF-kappaB activation, when the K1 protein is absent or mutated.
    Willis KL, Langland JO, Shisler JL.
    J Biol Chem; 2011 Mar 11; 286(10):7765-7778. PubMed ID: 21183678
    [Abstract] [Full Text] [Related]

  • 5. Mutational analysis of vaccinia virus E3 protein: the biological functions do not correlate with its biochemical capacity to bind double-stranded RNA.
    Dueck KJ, Hu YS, Chen P, Deschambault Y, Lee J, Varga J, Cao J.
    J Virol; 2015 May 11; 89(10):5382-94. PubMed ID: 25740987
    [Abstract] [Full Text] [Related]

  • 6. Roles of vaccinia virus genes E3L and K3L and host genes PKR and RNase L during intratracheal infection of C57BL/6 mice.
    Rice AD, Turner PC, Embury JE, Moldawer LL, Baker HV, Moyer RW.
    J Virol; 2011 Jan 11; 85(1):550-67. PubMed ID: 20943971
    [Abstract] [Full Text] [Related]

  • 7. Viral host-range factor C7 or K1 is essential for modified vaccinia virus Ankara late gene expression in human and murine cells, irrespective of their capacity to inhibit protein kinase R-mediated phosphorylation of eukaryotic translation initiation factor 2alpha.
    Backes S, Sperling KM, Zwilling J, Gasteiger G, Ludwig H, Kremmer E, Schwantes A, Staib C, Sutter G.
    J Gen Virol; 2010 Feb 11; 91(Pt 2):470-82. PubMed ID: 19846675
    [Abstract] [Full Text] [Related]

  • 8. Improvement of In Vivo Expression of Genes Delivered by Self-Amplifying RNA Using Vaccinia Virus Immune Evasion Proteins.
    Beissert T, Koste L, Perkovic M, Walzer KC, Erbar S, Selmi A, Diken M, Kreiter S, Türeci Ö, Sahin U.
    Hum Gene Ther; 2017 Dec 11; 28(12):1138-1146. PubMed ID: 28877647
    [Abstract] [Full Text] [Related]

  • 9. Protein kinase regulated by dsRNA downregulates the interferon production in dengue virus- and dsRNA-stimulated human lung epithelial cells.
    Li Y, Xie J, Wu S, Xia J, Zhang P, Liu C, Zhang P, Huang X.
    PLoS One; 2013 Dec 11; 8(1):e55108. PubMed ID: 23372823
    [Abstract] [Full Text] [Related]

  • 10. Highly Pathogenic New World Arenavirus Infection Activates the Pattern Recognition Receptor Protein Kinase R without Attenuating Virus Replication in Human Cells.
    Huang C, Kolokoltsova OA, Mateer EJ, Koma T, Paessler S.
    J Virol; 2017 Oct 15; 91(20):. PubMed ID: 28794024
    [Abstract] [Full Text] [Related]

  • 11. Improving Adaptive and Memory Immune Responses of an HIV/AIDS Vaccine Candidate MVA-B by Deletion of Vaccinia Virus Genes (C6L and K7R) Blocking Interferon Signaling Pathways.
    García-Arriaza J, Arnáez P, Gómez CE, Sorzano CÓ, Esteban M.
    PLoS One; 2013 Oct 15; 8(6):e66894. PubMed ID: 23826170
    [Abstract] [Full Text] [Related]

  • 12. Replication of modified vaccinia virus Ankara in primary chicken embryo fibroblasts requires expression of the interferon resistance gene E3L.
    Hornemann S, Harlin O, Staib C, Kisling S, Erfle V, Kaspers B, Häcker G, Sutter G.
    J Virol; 2003 Aug 15; 77(15):8394-407. PubMed ID: 12857909
    [Abstract] [Full Text] [Related]

  • 13. Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway.
    Dai P, Wang W, Cao H, Avogadri F, Dai L, Drexler I, Joyce JA, Li XD, Chen Z, Merghoub T, Shuman S, Deng L.
    PLoS Pathog; 2014 Apr 15; 10(4):e1003989. PubMed ID: 24743339
    [Abstract] [Full Text] [Related]

  • 14. Deletion of the vaccinia virus N2L gene encoding an inhibitor of IRF3 improves the immunogenicity of modified vaccinia virus Ankara expressing HIV-1 antigens.
    García-Arriaza J, Gómez CE, Sorzano CÓ, Esteban M.
    J Virol; 2014 Mar 15; 88(6):3392-410. PubMed ID: 24390336
    [Abstract] [Full Text] [Related]

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  • 17. Interference with SAMHD1 Restores Late Gene Expression of Modified Vaccinia Virus Ankara in Human Dendritic Cells and Abrogates Type I Interferon Expression.
    Sliva K, Martin J, von Rhein C, Herrmann T, Weyrich A, Toda M, Schnierle BS.
    J Virol; 2019 Nov 15; 93(22):. PubMed ID: 31462561
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  • 19. Structural study of novel vaccinia virus E3L and dsRNA-dependent protein kinase complex.
    Kim HJ, Han CW, Jeong MS, Jang SB.
    Biochem Biophys Res Commun; 2023 Jul 12; 665():1-9. PubMed ID: 37146409
    [Abstract] [Full Text] [Related]

  • 20. JNK-deficiency enhanced oncolytic vaccinia virus replication and blocked activation of double-stranded RNA-dependent protein kinase.
    Hu W, Hofstetter W, Guo W, Li H, Pataer A, Peng HH, Guo ZS, Bartlett DL, Lin A, Swisher SG, Fang B.
    Cancer Gene Ther; 2008 Sep 12; 15(9):616-24. PubMed ID: 18535619
    [Abstract] [Full Text] [Related]

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