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1317 related items for PubMed ID: 25301449

  • 1. SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo.
    Xia Y, Lei Q, Zhu Y, Ye T, Wang N, Li G, Shi X, Liu Y, Shao B, Yin T, Zhao L, Wu W, Song X, Xiong Y, Wei Y, Yu L.
    Cancer Lett; 2014 Dec 28; 355(2):297-309. PubMed ID: 25301449
    [Abstract] [Full Text] [Related]

  • 2. DAT-230, a novel microtubule inhibitor, exhibits potent anti-tumor activity by inducing G2/M phase arrest, apoptosis in vitro and perfusion decrease in vivo to HT-1080.
    Qiao F, Zuo D, Shen X, Qi H, Wang H, Zhang W, Wu Y.
    Cancer Chemother Pharmacol; 2012 Aug 28; 70(2):259-70. PubMed ID: 22752214
    [Abstract] [Full Text] [Related]

  • 3. Isoobtusilactone A induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal-regulating kinase 1 signaling pathway in human breast cancer cells.
    Kuo PL, Chen CY, Hsu YL.
    Cancer Res; 2007 Aug 01; 67(15):7406-20. PubMed ID: 17671211
    [Abstract] [Full Text] [Related]

  • 4. Millepachine, a novel chalcone, induces G2/M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo.
    Wu W, Ye H, Wan L, Han X, Wang G, Hu J, Tang M, Duan X, Fan Y, He S, Huang L, Pei H, Wang X, Li X, Xie C, Zhang R, Yuan Z, Mao Y, Wei Y, Chen L.
    Carcinogenesis; 2013 Jul 01; 34(7):1636-43. PubMed ID: 23471882
    [Abstract] [Full Text] [Related]

  • 5. Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
    Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.
    J Agric Food Chem; 2012 Jan 18; 60(2):665-75. PubMed ID: 22148415
    [Abstract] [Full Text] [Related]

  • 6. 12-Deoxyphorbol 13-palmitate mediated cell growth inhibition, G2-M cell cycle arrest and apoptosis in BGC823 cells.
    Xu HY, Chen ZW, Li H, Zhou L, Liu F, Lv YY, Liu JC.
    Eur J Pharmacol; 2013 Jan 30; 700(1-3):13-22. PubMed ID: 23220710
    [Abstract] [Full Text] [Related]

  • 7. Anti-Colon Cancer Effects of 6-Shogaol Through G2/M Cell Cycle Arrest by p53/p21-cdc2/cdc25A Crosstalk.
    Qi LW, Zhang Z, Zhang CF, Anderson S, Liu Q, Yuan CS, Wang CZ.
    Am J Chin Med; 2015 Jan 30; 43(4):743-56. PubMed ID: 26119958
    [Abstract] [Full Text] [Related]

  • 8. DICO, a novel nonaromatic B-ring flavonoid, induces G2/M cell cycle arrest and apoptosis in human hepatoma cells.
    Zhou D, Wei A, Cao C, Ruan J.
    Food Chem Toxicol; 2013 Jul 30; 57():322-9. PubMed ID: 23567243
    [Abstract] [Full Text] [Related]

  • 9. GL-V9, a newly synthetic flavonoid derivative, induces mitochondrial-mediated apoptosis and G2/M cell cycle arrest in human hepatocellular carcinoma HepG2 cells.
    Li L, Lu N, Dai Q, Wei L, Zhao Q, Li Z, He Q, Dai Y, Guo Q.
    Eur J Pharmacol; 2011 Nov 16; 670(1):13-21. PubMed ID: 21944925
    [Abstract] [Full Text] [Related]

  • 10. A novel derivative of quinazoline, WYK431 induces G2/M phase arrest and apoptosis in human gastric cancer BGC823 cells through the PI3K/Akt pathway.
    Wang TE, Wang YK, Jin J, Xu BL, Chen XG.
    Int J Oncol; 2014 Aug 16; 45(2):771-81. PubMed ID: 24859921
    [Abstract] [Full Text] [Related]

  • 11. MHY451 induces cell cycle arrest and apoptosis by ROS generation in HCT116 human colorectal cancer cells.
    Hwang NL, Kang YJ, Sung B, Hwang SY, Jang JY, Oh HJ, Ahn YR, Kim DH, Kim SJ, Ullah S, Hossain MA, Moon HR, Chung HY, Kim ND.
    Oncol Rep; 2017 Sep 16; 38(3):1783-1789. PubMed ID: 28731136
    [Abstract] [Full Text] [Related]

  • 12. Anti-tumor activity of SL4 against breast cancer cells: induction of G2/M arrest through modulation of the MAPK-dependent p21 signaling pathway.
    Wang LH, Jiang XR, Chen GL, Guo W, Zhang JY, Cui LJ, Li HH, Li M, Liu X, Yang JY, Wu CF.
    Sci Rep; 2016 Nov 07; 6():36486. PubMed ID: 27819344
    [Abstract] [Full Text] [Related]

  • 13. [Induction of G2 /M phase arrest and apoptosis of MCF-7 cells by novel benzofuran lignan via suppressing cell cycle proteins].
    Yang H, Cai YC, Pang JY, Li YQ, Zeng ZL, Xu ZL, Xian LJ.
    Yao Xue Xue Bao; 2008 Feb 07; 43(2):138-44. PubMed ID: 18507339
    [Abstract] [Full Text] [Related]

  • 14. The histone deacetylase inhibitor trichostatin A induces cell cycle arrest and apoptosis in colorectal cancer cells via p53-dependent and -independent pathways.
    Meng J, Zhang HH, Zhou CX, Li C, Zhang F, Mei QB.
    Oncol Rep; 2012 Jul 07; 28(1):384-8. PubMed ID: 22552631
    [Abstract] [Full Text] [Related]

  • 15. Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells.
    Wang CC, Chiang YM, Sung SC, Hsu YL, Chang JK, Kuo PL.
    Cancer Lett; 2008 Jan 18; 259(1):82-98. PubMed ID: 18023967
    [Abstract] [Full Text] [Related]

  • 16. Phenethyl isothiocyanate induces DNA damage-associated G2/M arrest and subsequent apoptosis in oral cancer cells with varying p53 mutations.
    Yeh YT, Yeh H, Su SH, Lin JS, Lee KJ, Shyu HW, Chen ZF, Huang SY, Su SJ.
    Free Radic Biol Med; 2014 Sep 18; 74():1-13. PubMed ID: 24952138
    [Abstract] [Full Text] [Related]

  • 17. ERK-modulated intrinsic signaling and G(2)/M phase arrest contribute to the induction of apoptotic death by allyl isothiocyanate in MDA-MB-468 human breast adenocarcinoma cells.
    Tsai SC, Huang WW, Huang WC, Lu CC, Chiang JH, Peng SF, Chung JG, Lin YH, Hsu YM, Amagaya S, Yang JS.
    Int J Oncol; 2012 Dec 18; 41(6):2065-72. PubMed ID: 23008020
    [Abstract] [Full Text] [Related]

  • 18. Bufotalin from Venenum Bufonis inhibits growth of multidrug resistant HepG2 cells through G2/M cell cycle arrest and apoptosis.
    Zhang DM, Liu JS, Tang MK, Yiu A, Cao HH, Jiang L, Chan JY, Tian HY, Fung KP, Ye WC.
    Eur J Pharmacol; 2012 Oct 05; 692(1-3):19-28. PubMed ID: 22841670
    [Abstract] [Full Text] [Related]

  • 19. Romidepsin induces G2/M phase arrest via Erk/cdc25C/cdc2/cyclinB pathway and apoptosis induction through JNK/c-Jun/caspase3 pathway in hepatocellular carcinoma cells.
    Sun WJ, Huang H, He B, Hu DH, Li PH, Yu YJ, Zhou XH, Lv Z, Zhou L, Hu TY, Yao ZC, Lu MD, Shen X, Zheng ZQ.
    Biochem Pharmacol; 2017 Mar 01; 127():90-100. PubMed ID: 28012958
    [Abstract] [Full Text] [Related]

  • 20. A monomer purified from Paris polyphylla (PP-22) triggers S and G2/M phase arrest and apoptosis in human tongue squamous cell carcinoma SCC-15 by activating the p38/cdc25/cdc2 and caspase 8/caspase 3 pathways.
    Ke JY, Zhang W, Gong RS, Cen WJ, Huang HQ, Li YR, Kong WD, Jiang JW.
    Tumour Biol; 2016 Nov 01; 37(11):14863-14872. PubMed ID: 27644244
    [Abstract] [Full Text] [Related]

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