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209 related items for PubMed ID: 25302649

  • 1. Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.
    Veigel D, Wagner R, Stübiger G, Wuczkowski M, Filipits M, Horvat R, Benhamú B, López-Rodríguez ML, Leisser A, Valent P, Grusch M, Hegardt FG, García J, Serra D, Auersperg N, Colomer R, Grunt TW.
    Int J Cancer; 2015 May 01; 136(9):2078-90. PubMed ID: 25302649
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  • 2. Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer.
    Corominas-Faja B, Vellon L, Cuyàs E, Buxó M, Martin-Castillo B, Serra D, García J, Lupu R, Menendez JA.
    Histol Histopathol; 2017 Jul 01; 32(7):687-698. PubMed ID: 27714708
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  • 3. Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells.
    Wagner R, Stübiger G, Veigel D, Wuczkowski M, Lanzerstorfer P, Weghuber J, Karteris E, Nowikovsky K, Wilfinger-Lutz N, Singer CF, Colomer R, Benhamú B, López-Rodríguez ML, Valent P, Grunt TW.
    Oncotarget; 2017 Feb 14; 8(7):11600-11613. PubMed ID: 28086243
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  • 5. Expression and roles of fatty acid synthase in hepatocellular carcinoma.
    Hao Q, Li T, Zhang X, Gao P, Qiao P, Li S, Geng Z.
    Oncol Rep; 2014 Dec 14; 32(6):2471-6. PubMed ID: 25231933
    [Abstract] [Full Text] [Related]

  • 6. Fatty acid synthase inhibition induces differential expression of genes involved in apoptosis and cell proliferation in ocular cancer cells.
    Deepa PR, Vandhana S, Krishnakumar S.
    Nutr Cancer; 2013 Dec 14; 65(2):311-6. PubMed ID: 23441619
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  • 7. Inhibitory effect of emodin on fatty acid synthase, colon cancer proliferation and apoptosis.
    Lee KH, Lee MS, Cha EY, Sul JY, Lee JS, Kim JS, Park JB, Kim JY.
    Mol Med Rep; 2017 Apr 14; 15(4):2163-2173. PubMed ID: 28260110
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  • 8. Pharmacological blockade of fatty acid synthase (FASN) reverses acquired autoresistance to trastuzumab (Herceptin by transcriptionally inhibiting 'HER2 super-expression' occurring in high-dose trastuzumab-conditioned SKBR3/Tzb100 breast cancer cells.
    Vazquez-Martin A, Colomer R, Brunet J, Menendez JA.
    Int J Oncol; 2007 Oct 14; 31(4):769-76. PubMed ID: 17786307
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  • 9. High prevalence of fatty acid synthase expression in colorectal cancers in Middle Eastern patients and its potential role as a therapeutic target.
    Uddin S, Hussain AR, Ahmed M, Abubaker J, Al-Sanea N, Abduljabbar A, Ashari LH, Alhomoud S, Al-Dayel F, Bavi P, Al-Kuraya KS.
    Am J Gastroenterol; 2009 Jul 14; 104(7):1790-801. PubMed ID: 19491830
    [Abstract] [Full Text] [Related]

  • 10. Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancer.
    Grunt TW, Slany A, Semkova M, Colomer R, López-Rodríguez ML, Wuczkowski M, Wagner R, Gerner C, Stübiger G.
    Sci Rep; 2020 Sep 10; 10(1):14877. PubMed ID: 32913236
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  • 13. Progress in the development of fatty acid synthase inhibitors as anticancer targets.
    Mullen GE, Yet L.
    Bioorg Med Chem Lett; 2015 Oct 15; 25(20):4363-9. PubMed ID: 26364942
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  • 14. Resensitizing Paclitaxel-Resistant Ovarian Cancer via Targeting Lipid Metabolism Key Enzymes CPT1A, SCD and FASN.
    Ma Q, Liu Z, Wang T, Zhao P, Liu M, Wang Y, Zhao W, Yuan Y, Li S.
    Int J Mol Sci; 2023 Nov 19; 24(22):. PubMed ID: 38003694
    [Abstract] [Full Text] [Related]

  • 15. Fatty acid synthase is a potential therapeutic target in estrogen receptor-/progesterone receptor-positive endometrioid endometrial cancer.
    Rahman MT, Nakayama K, Ishikawa M, Rahman M, Katagiri H, Katagiri A, Ishibashi T, Iida K, Miyazaki K.
    Oncology; 2013 Nov 19; 84(3):166-73. PubMed ID: 23306391
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  • 16. Expressions of fatty acid synthase and HER2 are correlated with poor prognosis of ovarian cancer.
    Cai Y, Wang J, Zhang L, Wu D, Yu D, Tian X, Liu J, Jiang X, Shen Y, Zhang L, Ren M, Huang P.
    Med Oncol; 2015 Jan 19; 32(1):391. PubMed ID: 25433947
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  • 17. Crosstalk between osteoprotegerin (OPG), fatty acid synthase (FASN) and, cycloxygenase-2 (COX-2) in breast cancer: implications in carcinogenesis.
    Goswami S, Sharma-Walia N.
    Oncotarget; 2016 Sep 13; 7(37):58953-58974. PubMed ID: 27270654
    [Abstract] [Full Text] [Related]

  • 18. Ovarian Cancer-Intrinsic Fatty Acid Synthase Prevents Anti-tumor Immunity by Disrupting Tumor-Infiltrating Dendritic Cells.
    Jiang L, Fang X, Wang H, Li D, Wang X.
    Front Immunol; 2018 Sep 13; 9():2927. PubMed ID: 30619288
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  • 19. Analyzing effects of extra-virgin olive oil polyphenols on breast cancer-associated fatty acid synthase protein expression using reverse-phase protein microarrays.
    Menendez JA, Vazquez-Martin A, Oliveras-Ferraros C, Garcia-Villalba R, Carrasco-Pancorbo A, Fernandez-Gutierrez A, Segura-Carretero A.
    Int J Mol Med; 2008 Oct 13; 22(4):433-9. PubMed ID: 18813848
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  • 20. In vitro model of normal, immortalized ovarian surface epithelial and ovarian cancer cells for chemoprevention of ovarian cancer.
    Brewer M, Wharton JT, Wang J, McWatters A, Auersperg N, Gershenson D, Bast R, Zou C.
    Gynecol Oncol; 2005 Aug 13; 98(2):182-92. PubMed ID: 15907982
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