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644 related items for PubMed ID: 25304383

  • 1. Clitocine induces apoptosis and enhances the lethality of ABT-737 in human colon cancer cells by disrupting the interaction of Mcl-1 and Bak.
    Sun JG, Xiang J, Zeng XL, Li X, Wu P, Fung KP, Liu FY.
    Cancer Lett; 2014 Dec 28; 355(2):253-63. PubMed ID: 25304383
    [Abstract] [Full Text] [Related]

  • 2. Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation.
    Chen S, Dai Y, Harada H, Dent P, Grant S.
    Cancer Res; 2007 Jan 15; 67(2):782-91. PubMed ID: 17234790
    [Abstract] [Full Text] [Related]

  • 3. Clitocine potentiates TRAIL-mediated apoptosis in human colon cancer cells by promoting Mcl-1 degradation.
    Sun JG, Ruan F, Zeng XL, Xiang J, Li X, Wu P, Fung KP, Liu FY.
    Apoptosis; 2016 Oct 15; 21(10):1144-57. PubMed ID: 27421828
    [Abstract] [Full Text] [Related]

  • 4. Clitocine targets Mcl-1 to induce drug-resistant human cancer cell apoptosis in vitro and tumor growth inhibition in vivo.
    Sun JG, Li H, Li X, Zeng X, Wu P, Fung KP, Liu FY.
    Apoptosis; 2014 May 15; 19(5):871-82. PubMed ID: 24563182
    [Abstract] [Full Text] [Related]

  • 5. Efficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapy.
    Yamaguchi R, Janssen E, Perkins G, Ellisman M, Kitada S, Reed JC.
    PLoS One; 2011 May 15; 6(9):e24102. PubMed ID: 21949692
    [Abstract] [Full Text] [Related]

  • 6. Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer.
    Wesarg E, Hoffarth S, Wiewrodt R, Kröll M, Biesterfeld S, Huber C, Schuler M.
    Int J Cancer; 2007 Dec 01; 121(11):2387-94. PubMed ID: 17688235
    [Abstract] [Full Text] [Related]

  • 7. Platinum compounds sensitize ovarian carcinoma cells to ABT-737 by modulation of the Mcl-1/Noxa axis.
    Simonin K, N'Diaye M, Lheureux S, Loussouarn C, Dutoit S, Briand M, Giffard F, Brotin E, Blanc-Fournier C, Poulain L.
    Apoptosis; 2013 Apr 01; 18(4):492-508. PubMed ID: 23344663
    [Abstract] [Full Text] [Related]

  • 8. The Bcl-2/Bcl-XL family inhibitor ABT-737 sensitizes ovarian cancer cells to carboplatin.
    Witham J, Valenti MR, De-Haven-Brandon AK, Vidot S, Eccles SA, Kaye SB, Richardson A.
    Clin Cancer Res; 2007 Dec 01; 13(23):7191-8. PubMed ID: 18056200
    [Abstract] [Full Text] [Related]

  • 9. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
    Rahmani M, Aust MM, Attkisson E, Williams DC, Ferreira-Gonzalez A, Grant S.
    Cancer Res; 2013 Feb 15; 73(4):1340-51. PubMed ID: 23243017
    [Abstract] [Full Text] [Related]

  • 10. Ionizing radiation sensitizes breast cancer cells to Bcl-2 inhibitor, ABT-737, through regulating Mcl-1.
    Wu H, Schiff DS, Lin Y, Neboori HJ, Goyal S, Feng Z, Haffty BG.
    Radiat Res; 2014 Dec 15; 182(6):618-25. PubMed ID: 25409124
    [Abstract] [Full Text] [Related]

  • 11. The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.
    Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N.
    Hepatology; 2010 Oct 15; 52(4):1310-21. PubMed ID: 20799354
    [Abstract] [Full Text] [Related]

  • 12. Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737.
    Tahir SK, Yang X, Anderson MG, Morgan-Lappe SE, Sarthy AV, Chen J, Warner RB, Ng SC, Fesik SW, Elmore SW, Rosenberg SH, Tse C.
    Cancer Res; 2007 Feb 01; 67(3):1176-83. PubMed ID: 17283153
    [Abstract] [Full Text] [Related]

  • 13. Actinomycin D synergistically enhances the efficacy of the BH3 mimetic ABT-737 by downregulating Mcl-1 expression.
    Olberding KE, Wang X, Zhu Y, Pan J, Rai SN, Li C.
    Cancer Biol Ther; 2010 Nov 01; 10(9):918-29. PubMed ID: 20818182
    [Abstract] [Full Text] [Related]

  • 14. S1, a novel pan-BH3 mimetic, induces apoptosis in Mcl-1-overexpressing cells through Bak.
    Song T, Chang X, Zhang Z, Liu Y, Shen X.
    J Pharmacol Sci; 2012 Nov 01; 119(4):330-40. PubMed ID: 22814102
    [Abstract] [Full Text] [Related]

  • 15. Targeting multiple arms of the apoptotic regulatory machinery.
    Dai Y, Grant S.
    Cancer Res; 2007 Apr 01; 67(7):2908-11. PubMed ID: 17409392
    [Abstract] [Full Text] [Related]

  • 16. The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.
    van Delft MF, Wei AH, Mason KD, Vandenberg CJ, Chen L, Czabotar PE, Willis SN, Scott CL, Day CL, Cory S, Adams JM, Roberts AW, Huang DC.
    Cancer Cell; 2006 Nov 01; 10(5):389-99. PubMed ID: 17097561
    [Abstract] [Full Text] [Related]

  • 17. MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex.
    Konopleva M, Milella M, Ruvolo P, Watts JC, Ricciardi MR, Korchin B, McQueen T, Bornmann W, Tsao T, Bergamo P, Mak DH, Chen W, McCubrey J, Tafuri A, Andreeff M.
    Leukemia; 2012 Apr 01; 26(4):778-87. PubMed ID: 22064351
    [Abstract] [Full Text] [Related]

  • 18. HSP90 inhibitor (NVP-AUY922) enhances the anti-cancer effect of BCL-2 inhibitor (ABT-737) in small cell lung cancer expressing BCL-2.
    Yang H, Lee MH, Park I, Jeon H, Choi J, Seo S, Kim SW, Koh GY, Park KS, Lee DH.
    Cancer Lett; 2017 Dec 28; 411():19-26. PubMed ID: 28987383
    [Abstract] [Full Text] [Related]

  • 19. Norcantharidin enhances ABT-737-induced apoptosis in hepatocellular carcinoma cells by transcriptional repression of Mcl-1.
    Zhang S, Li G, Ma X, Wang Y, Liu G, Feng L, Zhao Y, Zhang G, Wu Y, Ye X, Qin B, Lu J.
    Cell Signal; 2012 Sep 28; 24(9):1803-9. PubMed ID: 22609455
    [Abstract] [Full Text] [Related]

  • 20. Cafestol overcomes ABT-737 resistance in Mcl-1-overexpressed renal carcinoma Caki cells through downregulation of Mcl-1 expression and upregulation of Bim expression.
    Woo SM, Min KJ, Seo BR, Nam JO, Choi KS, Yoo YH, Kwon TK.
    Cell Death Dis; 2014 Nov 06; 5(11):e1514. PubMed ID: 25375379
    [Abstract] [Full Text] [Related]

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