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Journal Abstract Search

282 related items for PubMed ID: 25305559

  • 1. L312, a novel PPARγ ligand with potent anti-diabetic activity by selective regulation.
    Xie X, Zhou X, Chen W, Long L, Li W, Yang X, Li S, Wang L.
    Biochim Biophys Acta; 2015 Jan; 1850(1):62-72. PubMed ID: 25305559
    [Abstract] [Full Text] [Related]

  • 2. A novel selective peroxisome proliferator-activator receptor-gamma modulator-SPPARgammaM5 improves insulin sensitivity with diminished adverse cardiovascular effects.
    Chang CH, McNamara LA, Wu MS, Muise ES, Tan Y, Wood HB, Meinke PT, Thompson JR, Doebber TW, Berger JP, McCann ME.
    Eur J Pharmacol; 2008 Apr 14; 584(1):192-201. PubMed ID: 18346728
    [Abstract] [Full Text] [Related]

  • 3. Selective targeting of PPARγ by the natural product chelerythrine with a unique binding mode and improved antidiabetic potency.
    Zheng W, Qiu L, Wang R, Feng X, Han Y, Zhu Y, Chen D, Liu Y, Jin L, Li Y.
    Sci Rep; 2015 Jul 17; 5():12222. PubMed ID: 26183621
    [Abstract] [Full Text] [Related]

  • 4. A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity.
    Choi SS, Kim ES, Koh M, Lee SJ, Lim D, Yang YR, Jang HJ, Seo KA, Min SH, Lee IH, Park SB, Suh PG, Choi JH.
    J Biol Chem; 2014 Sep 19; 289(38):26618-26629. PubMed ID: 25100724
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  • 7. Insulin resistance and metabolic derangements in obese mice are ameliorated by a novel peroxisome proliferator-activated receptor γ-sparing thiazolidinedione.
    Chen Z, Vigueira PA, Chambers KT, Hall AM, Mitra MS, Qi N, McDonald WG, Colca JR, Kletzien RF, Finck BN.
    J Biol Chem; 2012 Jul 06; 287(28):23537-48. PubMed ID: 22621923
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  • 9. Enhancing insulin sensitivity by dual PPARγ partial agonist, β-catenin inhibitor: Design, synthesis of new αphthalimido-o-toluoyl2-aminothiazole hybrids.
    Mourad AAE, Mourad MAE.
    Life Sci; 2020 Oct 15; 259():118270. PubMed ID: 32814067
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  • 10. Identification of a novel selective agonist of PPARγ with no promotion of adipogenesis and less inhibition of osteoblastogenesis.
    Liu C, Feng T, Zhu N, Liu P, Han X, Chen M, Wang X, Li N, Li Y, Xu Y, Si S.
    Sci Rep; 2015 Apr 01; 5():9530. PubMed ID: 25827822
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  • 11. A novel peroxisome proliferator-activated receptor gamma ligand improves insulin sensitivity and promotes browning of white adipose tissue in obese mice.
    Wu D, Eeda V, Undi RB, Mann S, Stout M, Lim HY, Wang W.
    Mol Metab; 2021 Dec 01; 54():101363. PubMed ID: 34710641
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  • 12. Chebulagic acid from Terminalia chebula enhances insulin mediated glucose uptake in 3T3-L1 adipocytes via PPARγ signaling pathway.
    Shyni GL, Kavitha S, Indu S, Arya AD, Anusree SS, Vineetha VP, Vandana S, Sundaresan A, Raghu KG.
    Biofactors; 2014 Dec 01; 40(6):646-57. PubMed ID: 25529897
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  • 13. LT175 is a novel PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic properties.
    Gilardi F, Giudici M, Mitro N, Maschi O, Guerrini U, Rando G, Maggi A, Cermenati G, Laghezza A, Loiodice F, Pochetti G, Lavecchia A, Caruso D, De Fabiani E, Bamberg K, Crestani M.
    J Biol Chem; 2014 Mar 07; 289(10):6908-6920. PubMed ID: 24451380
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  • 14. A novel specific peroxisome proliferator-activated receptor γ (PPARγ) modulator YR4-42 ameliorates hyperglycaemia and dyslipidaemia and hepatic steatosis in diet-induced obese mice.
    Huan Y, Pan X, Peng J, Jia C, Sun S, Bai G, Wang X, Zhou T, Li R, Liu S, Li C, Liu Q, Liu Z, Shen Z.
    Diabetes Obes Metab; 2019 Nov 07; 21(11):2553-2563. PubMed ID: 31364797
    [Abstract] [Full Text] [Related]

  • 15. C333H ameliorated insulin resistance through selectively modulating peroxisome proliferator-activated receptor γ in brown adipose tissue of db/db mice.
    Zhang N, Chen W, Zhou X, Zhou X, Xie X, Meng A, Li S, Wang L.
    Biol Pharm Bull; 2013 Nov 07; 36(6):980-7. PubMed ID: 23563593
    [Abstract] [Full Text] [Related]

  • 16. Effects of DSP-8658, a novel selective peroxisome proliferator-activated receptors a/γ modulator, on adipogenesis and glucose metabolism in diabetic obese mice.
    Goto T, Nakayama R, Yamanaka M, Takata M, Takazawa T, Watanabe K, Maruta K, Nagata R, Nagamine J, Tsuchida A, Kato H.
    Exp Clin Endocrinol Diabetes; 2015 Sep 07; 123(8):492-9. PubMed ID: 26011171
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  • 17. Discovery of a novel selective PPARγ ligand with partial agonist binding properties by integrated in silico/in vitro work flow.
    Kouskoumvekaki I, Petersen RK, Fratev F, Taboureau O, Nielsen TE, Oprea TI, Sonne SB, Flindt EN, Jónsdóttir SÓ, Kristiansen K.
    J Chem Inf Model; 2013 Apr 22; 53(4):923-37. PubMed ID: 23432662
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  • 18. N-Acetylfarnesylcysteine is a novel class of peroxisome proliferator-activated receptor γ ligand with partial and full agonist activity in vitro and in vivo.
    Bhalla K, Hwang BJ, Choi JH, Dewi R, Ou L, Mclenithan J, Twaddel W, Pozharski E, Stock J, Girnun GD.
    J Biol Chem; 2011 Dec 02; 286(48):41626-41635. PubMed ID: 21979952
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  • 19. CMHX008, a novel peroxisome proliferator-activated receptor γ partial agonist, enhances insulin sensitivity in vitro and in vivo.
    Ming Y, Hu X, Song Y, Liu Z, Li J, Gao R, Zhang Y, Mei H, Guo T, Xiao L, Wang B, Wu C, Xiao X.
    PLoS One; 2014 Dec 02; 9(7):e102102. PubMed ID: 25004107
    [Abstract] [Full Text] [Related]

  • 20. Structure-based screening and biological validation of the anti-thrombotic drug-dicoumarol as a novel and potent PPARγ-modulating ligand.
    Ma L, Tang J, Cai G, Chen F, Liu Q, Zhou Z, Zhang S, Liu X, Hou N, Yi W.
    Bioorg Chem; 2022 Dec 02; 129():106191. PubMed ID: 36270169
    [Abstract] [Full Text] [Related]

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