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Journal Abstract Search

535 related items for PubMed ID: 25341796

  • 1. Induction of sustained hypercholesterolemia by single adeno-associated virus-mediated gene transfer of mutant hPCSK9.
    Roche-Molina M, Sanz-Rosa D, Cruz FM, García-Prieto J, López S, Abia R, Muriana FJ, Fuster V, Ibáñez B, Bernal JA.
    Arterioscler Thromb Vasc Biol; 2015 Jan; 35(1):50-9. PubMed ID: 25341796
    [Abstract] [Full Text] [Related]

  • 2. Hypercholesterolemia Induced by a PCSK9 Gain-of-Function Mutation Augments Angiotensin II-Induced Abdominal Aortic Aneurysms in C57BL/6 Mice-Brief Report.
    Lu H, Howatt DA, Balakrishnan A, Graham MJ, Mullick AE, Daugherty A.
    Arterioscler Thromb Vasc Biol; 2016 Sep; 36(9):1753-7. PubMed ID: 27470509
    [Abstract] [Full Text] [Related]

  • 3. Activation of Adiponectin Receptor Regulates Proprotein Convertase Subtilisin/Kexin Type 9 Expression and Inhibits Lesions in ApoE-Deficient Mice.
    Sun L, Yang X, Li Q, Zeng P, Liu Y, Liu L, Chen Y, Yu M, Ma C, Li X, Li Y, Zhang R, Zhu Y, Miao QR, Han J, Duan Y.
    Arterioscler Thromb Vasc Biol; 2017 Jul; 37(7):1290-1300. PubMed ID: 28546220
    [Abstract] [Full Text] [Related]

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  • 5. STK25 Regulates Cardiovascular Disease Progression in a Mouse Model of Hypercholesterolemia.
    Cansby E, Magnusson E, Nuñez-Durán E, Amrutkar M, Pedrelli M, Parini P, Hoffmann J, Ståhlman M, Howell BW, Marschall HU, Borén J, Mahlapuu M.
    Arterioscler Thromb Vasc Biol; 2018 Aug; 38(8):1723-1737. PubMed ID: 29930001
    [Abstract] [Full Text] [Related]

  • 6. PCSK9 inhibition fails to alter hepatic LDLR, circulating cholesterol, and atherosclerosis in the absence of ApoE.
    Ason B, van der Hoorn JW, Chan J, Lee E, Pieterman EJ, Nguyen KK, Di M, Shetterly S, Tang J, Yeh WC, Schwarz M, Jukema JW, Scott R, Wasserman SM, Princen HM, Jackson S.
    J Lipid Res; 2014 Nov; 55(11):2370-9. PubMed ID: 25258384
    [Abstract] [Full Text] [Related]

  • 7. Absence of Nicotinamide Nucleotide Transhydrogenase in C57BL/6J Mice Exacerbates Experimental Atherosclerosis.
    Vozenilek AE, Vetkoetter M, Green JM, Shen X, Traylor JG, Klein RL, Orr AW, Woolard MD, Krzywanski DM.
    J Vasc Res; 2018 Nov; 55(2):98-110. PubMed ID: 29455203
    [Abstract] [Full Text] [Related]

  • 8. AAV vectors expressing LDLR gain-of-function variants demonstrate increased efficacy in mouse models of familial hypercholesterolemia.
    Somanathan S, Jacobs F, Wang Q, Hanlon AL, Wilson JM, Rader DJ.
    Circ Res; 2014 Aug 29; 115(6):591-9. PubMed ID: 25023731
    [Abstract] [Full Text] [Related]

  • 9. Local effects of human PCSK9 on the atherosclerotic lesion.
    Giunzioni I, Tavori H, Covarrubias R, Major AS, Ding L, Zhang Y, DeVay RM, Hong L, Fan D, Predazzi IM, Rashid S, Linton MF, Fazio S.
    J Pathol; 2016 Jan 29; 238(1):52-62. PubMed ID: 26333678
    [Abstract] [Full Text] [Related]

  • 10. Accelerating the pace of atherosclerosis research.
    Daugherty A, Tabas I, Rader DJ.
    Arterioscler Thromb Vasc Biol; 2015 Jan 29; 35(1):11-2. PubMed ID: 25520521
    [No Abstract] [Full Text] [Related]

  • 11. New role of PCSK9 in atherosclerotic inflammation promotion involving the TLR4/NF-κB pathway.
    Tang ZH, Peng J, Ren Z, Yang J, Li TT, Li TH, Wang Z, Wei DH, Liu LS, Zheng XL, Jiang ZS.
    Atherosclerosis; 2017 Jul 29; 262():113-122. PubMed ID: 28535426
    [Abstract] [Full Text] [Related]

  • 12. Gene inactivation of proprotein convertase subtilisin/kexin type 9 reduces atherosclerosis in mice.
    Denis M, Marcinkiewicz J, Zaid A, Gauthier D, Poirier S, Lazure C, Seidah NG, Prat A.
    Circulation; 2012 Feb 21; 125(7):894-901. PubMed ID: 22261195
    [Abstract] [Full Text] [Related]

  • 13. Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research.
    Jarrett KE, Lee C, De Giorgi M, Hurley A, Gillard BK, Doerfler AM, Li A, Pownall HJ, Bao G, Lagor WR.
    Arterioscler Thromb Vasc Biol; 2018 Sep 21; 38(9):1997-2006. PubMed ID: 30026278
    [Abstract] [Full Text] [Related]

  • 14. A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification.
    Goettsch C, Hutcheson JD, Hagita S, Rogers MA, Creager MD, Pham T, Choi J, Mlynarchik AK, Pieper B, Kjolby M, Aikawa M, Aikawa E.
    Atherosclerosis; 2016 Aug 21; 251():109-118. PubMed ID: 27318830
    [Abstract] [Full Text] [Related]

  • 15. Reducing Vascular Calcification by Anti-IL-1β Monoclonal Antibody in a Mouse Model of Familial Hypercholesterolemia.
    Awan Z, Denis M, Roubtsova A, Essalmani R, Marcinkiewicz J, Awan A, Gram H, Seidah NG, Genest J.
    Angiology; 2016 Feb 21; 67(2):157-67. PubMed ID: 25904765
    [Abstract] [Full Text] [Related]

  • 16. Increased secretion of lipoproteins in transgenic mice expressing human D374Y PCSK9 under physiological genetic control.
    Herbert B, Patel D, Waddington SN, Eden ER, McAleenan A, Sun XM, Soutar AK.
    Arterioscler Thromb Vasc Biol; 2010 Jul 21; 30(7):1333-9. PubMed ID: 20448210
    [Abstract] [Full Text] [Related]

  • 17. Expression of type IIA secretory phospholipase A2 inhibits cholesteryl ester transfer protein activity in transgenic mice.
    Hurt-Camejo E, Gautier T, Rosengren B, Dikkers A, Behrendt M, Grass DS, Rader DJ, Tietge UJ.
    Arterioscler Thromb Vasc Biol; 2013 Dec 21; 33(12):2707-14. PubMed ID: 24115030
    [Abstract] [Full Text] [Related]

  • 18. Targeting the proprotein convertase subtilisin/kexin type 9 for the treatment of dyslipidemia and atherosclerosis.
    Urban D, Pöss J, Böhm M, Laufs U.
    J Am Coll Cardiol; 2013 Oct 15; 62(16):1401-8. PubMed ID: 23973703
    [Abstract] [Full Text] [Related]

  • 19. Serum proprotein convertase subtilisin/kexin type 9 and cell surface low-density lipoprotein receptor: evidence for a reciprocal regulation.
    Tavori H, Fan D, Blakemore JL, Yancey PG, Ding L, Linton MF, Fazio S.
    Circulation; 2013 Jun 18; 127(24):2403-13. PubMed ID: 23690465
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of PCSK9: a novel approach for the treatment of dyslipidemia.
    Stawowy P, Just IA, Kaschina E.
    Coron Artery Dis; 2014 Jun 18; 25(4):353-9. PubMed ID: 24667128
    [Abstract] [Full Text] [Related]

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